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Mucosal Melanoma of the Head and Neck

MedGen UID:
1612951
Concept ID:
C4524458
Neoplastic Process

Definition

A melanoma that arises in the mucosa of the nasal cavity, paranasal sinuses, oral cavity, oropharynx, nasopharynx, larynx, and hypopharynx. [from NCI]

Professional guidelines

PubMed

Jeong YJ, Thompson JF, Ch'ng S
Chin Clin Oncol 2023 Jun;12(3):28. doi: 10.21037/cco-23-16. PMID: 37417292
Wehbe J, Jaikaransingh D, Walker A
Medicine (Baltimore) 2022 Aug 5;101(31):e29979. doi: 10.1097/MD.0000000000029979. PMID: 35945708Free PMC Article
Moreno MA, Hanna EY
Curr Opin Otolaryngol Head Neck Surg 2010 Apr;18(2):101-6. doi: 10.1097/MOO.0b013e3283374d31. PMID: 20234212

Recent clinical studies

Etiology

Jeong YJ, Thompson JF, Ch'ng S
Chin Clin Oncol 2023 Jun;12(3):28. doi: 10.21037/cco-23-16. PMID: 37417292
Ricci C, Altavilla MV, Corti B, Pasquini E, Presutti L, Baietti AM, Amorosa L, Balbi T, Baldovini C, Ambrosi F, Grillini M, D'Errico A, Fiorentino M, Foschini MP
Am J Surg Pathol 2023 May 1;47(5):599-610. Epub 2023 Mar 13 doi: 10.1097/PAS.0000000000002032. PMID: 36912431Free PMC Article
Ascierto PA, Accorona R, Botti G, Farina D, Fossati P, Gatta G, Gogas H, Lombardi D, Maroldi R, Nicolai P, Ravanelli M, Vanella V
Crit Rev Oncol Hematol 2017 Apr;112:136-152. Epub 2017 Feb 13 doi: 10.1016/j.critrevonc.2017.01.019. PMID: 28325255
Frakes JM, Strom TJ, Naghavi AO, Trotti A, Rao NG, McCaffrey JC, Otto KJ, Padhya T, Caudell JJ
J Med Imaging Radiat Oncol 2016 Apr;60(2):268-73. Epub 2015 Nov 23 doi: 10.1111/1754-9485.12404. PMID: 26597431
Bakkal FK, Başman A, Kızıl Y, Ekinci Ö, Gümüşok M, Ekrem Zorlu M, Aydil U
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Nov;120(5):575-80. Epub 2015 Jul 6 doi: 10.1016/j.oooo.2015.06.038. PMID: 26260765

Diagnosis

Ricci C, Altavilla MV, Corti B, Pasquini E, Presutti L, Baietti AM, Amorosa L, Balbi T, Baldovini C, Ambrosi F, Grillini M, D'Errico A, Fiorentino M, Foschini MP
Am J Surg Pathol 2023 May 1;47(5):599-610. Epub 2023 Mar 13 doi: 10.1097/PAS.0000000000002032. PMID: 36912431Free PMC Article
Sahovaler A, Ziai H, Cardemil F, Huang SH, Su J, Goldstein DP, Gilbert R, Hosni A, Hope A, Waldron J, Spreafico A, Monteiro E, Witterick I, Irish J, Gullane P, Xu W, O'Sullivan B, de Almeida JR
Laryngoscope 2021 Oct;131(10):2269-2276. Epub 2021 Apr 15 doi: 10.1002/lary.29555. PMID: 33856051
Bakkal FK, Başman A, Kızıl Y, Ekinci Ö, Gümüşok M, Ekrem Zorlu M, Aydil U
Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Nov;120(5):575-80. Epub 2015 Jul 6 doi: 10.1016/j.oooo.2015.06.038. PMID: 26260765
Lazarev S, Gupta V, Hu K, Harrison LB, Bakst R
Int J Radiat Oncol Biol Phys 2014 Dec 1;90(5):1108-18. doi: 10.1016/j.ijrobp.2014.03.042. PMID: 25539369
Bradley PJ
Curr Opin Otolaryngol Head Neck Surg 2006 Apr;14(2):100-4. doi: 10.1097/01.moo.0000193176.54450.c4. PMID: 16552267

Therapy

Sahovaler A, Ziai H, Cardemil F, Huang SH, Su J, Goldstein DP, Gilbert R, Hosni A, Hope A, Waldron J, Spreafico A, Monteiro E, Witterick I, Irish J, Gullane P, Xu W, O'Sullivan B, de Almeida JR
Laryngoscope 2021 Oct;131(10):2269-2276. Epub 2021 Apr 15 doi: 10.1002/lary.29555. PMID: 33856051
Ahn HJ, Na II, Park YH, Cho SY, Lee BC, Lee GH, Koh JS, Lee YS, Shim YS, Kim YK, Kang HJ, Ryoo BY, Yang SH
Oral Oncol 2010 Aug;46(8):607-11. Epub 2010 Jul 8 doi: 10.1016/j.oraloncology.2010.05.005. PMID: 20615750
Morris LG, Wen YH, Nonaka D, DeLacure MD, Kutler DI, Huan Y, Wang BY
Head Neck 2008 Jun;30(6):771-5. doi: 10.1002/hed.20785. PMID: 18228523
Bradley PJ
Curr Opin Otolaryngol Head Neck Surg 2006 Apr;14(2):100-4. doi: 10.1097/01.moo.0000193176.54450.c4. PMID: 16552267
Day TA, Hornig JD, Sharma AK, Brescia F, Gillespie MB, Lathers D
Curr Treat Options Oncol 2005 Jan;6(1):19-30. doi: 10.1007/s11864-005-0010-5. PMID: 15610712

Prognosis

Jeong YJ, Thompson JF, Ch'ng S
Chin Clin Oncol 2023 Jun;12(3):28. doi: 10.21037/cco-23-16. PMID: 37417292
Ricci C, Altavilla MV, Corti B, Pasquini E, Presutti L, Baietti AM, Amorosa L, Balbi T, Baldovini C, Ambrosi F, Grillini M, D'Errico A, Fiorentino M, Foschini MP
Am J Surg Pathol 2023 May 1;47(5):599-610. Epub 2023 Mar 13 doi: 10.1097/PAS.0000000000002032. PMID: 36912431Free PMC Article
Ascierto PA, Accorona R, Botti G, Farina D, Fossati P, Gatta G, Gogas H, Lombardi D, Maroldi R, Nicolai P, Ravanelli M, Vanella V
Crit Rev Oncol Hematol 2017 Apr;112:136-152. Epub 2017 Feb 13 doi: 10.1016/j.critrevonc.2017.01.019. PMID: 28325255
Frakes JM, Strom TJ, Naghavi AO, Trotti A, Rao NG, McCaffrey JC, Otto KJ, Padhya T, Caudell JJ
J Med Imaging Radiat Oncol 2016 Apr;60(2):268-73. Epub 2015 Nov 23 doi: 10.1111/1754-9485.12404. PMID: 26597431
Lazarev S, Gupta V, Hu K, Harrison LB, Bakst R
Int J Radiat Oncol Biol Phys 2014 Dec 1;90(5):1108-18. doi: 10.1016/j.ijrobp.2014.03.042. PMID: 25539369

Clinical prediction guides

Ricci C, Altavilla MV, Corti B, Pasquini E, Presutti L, Baietti AM, Amorosa L, Balbi T, Baldovini C, Ambrosi F, Grillini M, D'Errico A, Fiorentino M, Foschini MP
Am J Surg Pathol 2023 May 1;47(5):599-610. Epub 2023 Mar 13 doi: 10.1097/PAS.0000000000002032. PMID: 36912431Free PMC Article
Schmidt MQ, David J, Yoshida EJ, Scher K, Mita A, Shiao SL, Ho AS, Zumsteg ZS
Oral Oncol 2017 Oct;73:36-42. Epub 2017 Aug 10 doi: 10.1016/j.oraloncology.2017.08.002. PMID: 28939074
Plavc G, But-Hadžić J, Aničin A, Lanišnik B, Didanović V, Strojan P
Radiat Oncol 2016 Oct 14;11(1):137. doi: 10.1186/s13014-016-0712-9. PMID: 27737700Free PMC Article
Lawaetz M, Birch-Johansen F, Friis S, Eriksen JG, Kiss K, Gade S, Møller-Madsen M, Pourbordbari N, von Buchwald C
Acta Oncol 2016 Aug;55(8):1001-8. Epub 2016 Mar 31 doi: 10.3109/0284186X.2016.1143117. PMID: 27031263
Bradley PJ
Curr Opin Otolaryngol Head Neck Surg 2006 Apr;14(2):100-4. doi: 10.1097/01.moo.0000193176.54450.c4. PMID: 16552267

Recent systematic reviews

Wehbe J, Jaikaransingh D, Walker A
Medicine (Baltimore) 2022 Aug 5;101(31):e29979. doi: 10.1097/MD.0000000000029979. PMID: 35945708Free PMC Article
Lazarev S, Gupta V, Hu K, Harrison LB, Bakst R
Int J Radiat Oncol Biol Phys 2014 Dec 1;90(5):1108-18. doi: 10.1016/j.ijrobp.2014.03.042. PMID: 25539369
Kottschade LA, Grotz TE, Dronca RS, Salomao DR, Pulido JS, Wasif N, Jakub JW, Bagaria SP, Kumar R, Kaur JS, Morita SY, Moran SL, Nguyen JT, Nguyen EC, Hand JL, Erickson LA, Brewer JD, Baum CL, Miller RC, Swanson DL, Lowe V, Markovic SN
Am J Clin Oncol 2014 Dec;37(6):635-41. doi: 10.1097/COC.0b013e3182868e82. PMID: 23563206Free PMC Article

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