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Head and neck cancer

MedGen UID:
78920
Concept ID:
C0278996
Neoplastic Process
Synonyms: Cancer of Head and Neck; Cancer of the Head and Neck; Head and Neck Cancer
SNOMED CT: Malignant tumor of head and/or neck (255056009); Malignant tumor of head and neck (255056009)
 
Monarch Initiative: MONDO:0005627

Definition

A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Head and neck cancer

Professional guidelines

PubMed

Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Capella DL, Gonçalves JM, Abrantes AAA, Grando LJ, Daniel FI
Braz J Otorhinolaryngol 2017 Sep-Oct;83(5):585-593. Epub 2017 Jan 24 doi: 10.1016/j.bjorl.2016.12.005. PMID: 28209441Free PMC Article
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Curated

UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023

NCCN, Head and Neck, 2.2022

Recent clinical studies

Etiology

Juszczak HM, Rosenfeld RM
Otolaryngol Clin North Am 2022 Oct;55(5):909-927. Epub 2022 Sep 7 doi: 10.1016/j.otc.2022.06.001. PMID: 36088162
Gonçalves KKN, de Araújo ESM, Barbirato DS, do Lago CAP, do Egito Vasconcelos BC
Int J Oral Maxillofac Surg 2022 Jul;51(7):847-853. Epub 2021 Oct 1 doi: 10.1016/j.ijom.2021.08.011. PMID: 34602319
Porcheri C, Mitsiadis TA
Adv Exp Med Biol 2021;1287:81-103. doi: 10.1007/978-3-030-55031-8_7. PMID: 33034028
Rahman QB, Iocca O, Kufta K, Shanti RM
Oral Maxillofac Surg Clin North Am 2020 Aug;32(3):367-375. Epub 2020 May 29 doi: 10.1016/j.coms.2020.04.002. PMID: 32482563
Cervenka BP, Rao S, Bewley AF
Otolaryngol Clin North Am 2018 Aug;51(4):741-751. Epub 2018 May 23 doi: 10.1016/j.otc.2018.03.004. PMID: 29801920

Diagnosis

Gonçalves KKN, de Araújo ESM, Barbirato DS, do Lago CAP, do Egito Vasconcelos BC
Int J Oral Maxillofac Surg 2022 Jul;51(7):847-853. Epub 2021 Oct 1 doi: 10.1016/j.ijom.2021.08.011. PMID: 34602319
Müller Bark J, Kulasinghe A, Amenábar JM, Punyadeera C
Adv Clin Chem 2021;101:1-40. Epub 2020 Aug 18 doi: 10.1016/bs.acc.2020.06.006. PMID: 33706886
Yan K, Agrawal N, Gooi Z
Med Clin North Am 2018 Nov;102(6):1013-1025. Epub 2018 Sep 20 doi: 10.1016/j.mcna.2018.06.012. PMID: 30342605
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Svider PF, Blasco MA, Raza SN, Shkoukani M, Sukari A, Yoo GH, Folbe AJ, Lin HS, Fribley AM
Otolaryngol Head Neck Surg 2017 Jan;156(1):10-13. Epub 2016 Nov 14 doi: 10.1177/0194599816674672. PMID: 28045631

Therapy

Lacas B, Carmel A, Landais C, Wong SJ, Licitra L, Tobias JS, Burtness B, Ghi MG, Cohen EEW, Grau C, Wolf G, Hitt R, Corvò R, Budach V, Kumar S, Laskar SG, Mazeron JJ, Zhong LP, Dobrowsky W, Ghadjar P, Fallai C, Zakotnik B, Sharma A, Bensadoun RJ, Ruo Redda MG, Racadot S, Fountzilas G, Brizel D, Rovea P, Argiris A, Nagy ZT, Lee JW, Fortpied C, Harris J, Bourhis J, Aupérin A, Blanchard P, Pignon JP; MACH-NC Collaborative Group
Radiother Oncol 2021 Mar;156:281-293. Epub 2021 Jan 27 doi: 10.1016/j.radonc.2021.01.013. PMID: 33515668Free PMC Article
Wang C, Dickie J, Sutavani RV, Pointer C, Thomas GJ, Savelyeva N
Front Immunol 2018;9:830. Epub 2018 Apr 23 doi: 10.3389/fimmu.2018.00830. PMID: 29740440Free PMC Article
Ng WT, Wong ECY, Lee VHF, Chan JYW, Lee AWM
Jpn J Clin Oncol 2018 Jan 1;48(1):13-21. doi: 10.1093/jjco/hyx151. PMID: 29145620
Fukuhara H, Ino Y, Todo T
Cancer Sci 2016 Oct;107(10):1373-1379. Epub 2016 Sep 9 doi: 10.1111/cas.13027. PMID: 27486853Free PMC Article
Homma A, Onimaru R, Matsuura K, Robbins KT, Fujii M
Jpn J Clin Oncol 2016 Jan;46(1):4-12. Epub 2015 Oct 20 doi: 10.1093/jjco/hyv151. PMID: 26486825

Prognosis

Aragón N, Ordoñez D, Urrea MF, Holguín J, Collazos P, García LS, Osorio MC, Barreto JM, Bravo LE
Community Dent Oral Epidemiol 2022 Aug;50(4):292-299. Epub 2021 Jun 8 doi: 10.1111/cdoe.12671. PMID: 34105170Free PMC Article
Olsen SH, Friborg J, Ellefsen B, Jakobsen KK, Aanæs K
Int J Circumpolar Health 2021 Dec;80(1):1894697. doi: 10.1080/22423982.2021.1894697. PMID: 33719929Free PMC Article
Frowen J
Curr Opin Otolaryngol Head Neck Surg 2019 Jun;27(3):162-167. doi: 10.1097/MOO.0000000000000541. PMID: 30946062
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
De Felice F, de Vincentiis M, Valentini V, Musio D, Mezi S, Lo Mele L, Terenzi V, D'Aguanno V, Cassoni A, Di Brino M, Tenore G, Bulzonetti N, Battisti A, Greco A, Pompa G, Minni A, Romeo U, Cortesi E, Polimeni A, Tombolini V
Crit Rev Oncol Hematol 2017 May;113:151-155. Epub 2017 Mar 14 doi: 10.1016/j.critrevonc.2017.03.012. PMID: 28427504

Clinical prediction guides

Lewis S, Pandey S, Salins N, Deodhar J, Patil V, Gupta T, Laskar SG, Budrukkar A, Murthy V, Joshi A, Prabhash K, Nair S, Chaturvedi P, Noronha V, Agarwal JP
Laryngoscope 2021 Sep;131(9):2023-2029. Epub 2021 Mar 15 doi: 10.1002/lary.29491. PMID: 33720420
Bossi P, Resteghini C, Paielli N, Licitra L, Pilotti S, Perrone F
Oncotarget 2016 Nov 8;7(45):74362-74379. doi: 10.18632/oncotarget.11413. PMID: 27556186Free PMC Article
Moloney EC, Brunner M, Alexander AJ, Clark J
Head Neck 2015 Aug;37(8):1225-31. Epub 2014 Jul 11 doi: 10.1002/hed.23722. PMID: 24797251
Nelke KH, Pawlak W, Gerber H, Leszczyszyn J
Adv Clin Exp Med 2014 Nov-Dec;23(6):1019-27. doi: 10.17219/acem/37361. PMID: 25618131
Vigneswaran N, Williams MD
Oral Maxillofac Surg Clin North Am 2014 May;26(2):123-41. doi: 10.1016/j.coms.2014.01.001. PMID: 24794262Free PMC Article

Recent systematic reviews

Bossola M, Antocicco M, Pepe G
JPEN J Parenter Enteral Nutr 2022 Aug;46(6):1258-1269. Epub 2022 May 22 doi: 10.1002/jpen.2360. PMID: 35244947
Mäkitie AA, Alabi RO, Orell H, Youssef O, Almangush A, Homma A, Takes RP, López F, de Bree R, Rodrigo JP, Ferlito A
Adv Ther 2022 Apr;39(4):1502-1523. Epub 2022 Feb 27 doi: 10.1007/s12325-022-02074-9. PMID: 35224702Free PMC Article
Banda KJ, Chu H, Kao CC, Voss J, Chiu HL, Chang PC, Chen R, Chou KR
Int J Nurs Stud 2021 Feb;114:103827. Epub 2020 Nov 11 doi: 10.1016/j.ijnurstu.2020.103827. PMID: 33352439
Dort JC, Farwell DG, Findlay M, Huber GF, Kerr P, Shea-Budgell MA, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J
JAMA Otolaryngol Head Neck Surg 2017 Mar 1;143(3):292-303. doi: 10.1001/jamaoto.2016.2981. PMID: 27737447
Cohen EE, LaMonte SJ, Erb NL, Beckman KL, Sadeghi N, Hutcheson KA, Stubblefield MD, Abbott DM, Fisher PS, Stein KD, Lyman GH, Pratt-Chapman ML
CA Cancer J Clin 2016 May;66(3):203-39. Epub 2016 Mar 22 doi: 10.3322/caac.21343. PMID: 27002678

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE Guideline NG12, Suspected cancer: recognition and referral, 2023
    • NCCN, 2023
      NCCN, Head and Neck, 2.2022

    Consumer resources

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