U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Head and neck cancer

MedGen UID:
78920
Concept ID:
C0278996
Neoplastic Process
Synonyms: Cancer of Head and Neck; Cancer of the Head and Neck; Head and Neck Cancer
SNOMED CT: Malignant tumor of head and/or neck (255056009); Malignant tumor of head and neck (255056009)
 
Monarch Initiative: MONDO:0005627

Definition

A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Head and neck cancer

Professional guidelines

PubMed

Capella DL, Gonçalves JM, Abrantes AAA, Grando LJ, Daniel FI
Braz J Otorhinolaryngol 2017 Sep-Oct;83(5):585-593. Epub 2017 Jan 24 doi: 10.1016/j.bjorl.2016.12.005. PMID: 28209441Free PMC Article
Dort JC, Farwell DG, Findlay M, Huber GF, Kerr P, Shea-Budgell MA, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J
JAMA Otolaryngol Head Neck Surg 2017 Mar 1;143(3):292-303. doi: 10.1001/jamaoto.2016.2981. PMID: 27737447
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Curated

NCCN, Head and Neck, 2.2022

Recent clinical studies

Etiology

Cantwell LA, Fahy E, Walters ER, Patterson JM
Support Care Cancer 2022 Nov;30(11):8831-8843. Epub 2022 Aug 1 doi: 10.1007/s00520-022-07239-4. PMID: 35913625
Yang W, Nie W, Zhou X, Guo W, Mou J, Yong J, Wu T, Liu X
Int J Nurs Stud 2021 Nov;123:104074. Epub 2021 Aug 27 doi: 10.1016/j.ijnurstu.2021.104074. PMID: 34536908
Müller-Richter U, Betz C, Hartmann S, Brands RC
Nutr Res 2017 Dec;48:1-8. Epub 2017 Aug 25 doi: 10.1016/j.nutres.2017.08.007. PMID: 29246276
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Rettig EM, D'Souza G
Surg Oncol Clin N Am 2015 Jul;24(3):379-96. Epub 2015 Apr 9 doi: 10.1016/j.soc.2015.03.001. PMID: 25979389

Diagnosis

Jiang S, Li X, Huang L, Xu Z, Lin J
Front Immunol 2022;13:988416. Epub 2022 Sep 2 doi: 10.3389/fimmu.2022.988416. PMID: 36119046Free PMC Article
Cantwell LA, Fahy E, Walters ER, Patterson JM
Support Care Cancer 2022 Nov;30(11):8831-8843. Epub 2022 Aug 1 doi: 10.1007/s00520-022-07239-4. PMID: 35913625
Müller Bark J, Kulasinghe A, Amenábar JM, Punyadeera C
Adv Clin Chem 2021;101:1-40. Epub 2020 Aug 18 doi: 10.1016/bs.acc.2020.06.006. PMID: 33706886
Huang SH, O'Sullivan B
Curr Treat Options Oncol 2017 Jul;18(7):40. doi: 10.1007/s11864-017-0484-y. PMID: 28555375
Svider PF, Blasco MA, Raza SN, Shkoukani M, Sukari A, Yoo GH, Folbe AJ, Lin HS, Fribley AM
Otolaryngol Head Neck Surg 2017 Jan;156(1):10-13. Epub 2016 Nov 14 doi: 10.1177/0194599816674672. PMID: 28045631

Therapy

Alsubaie HM, Alsini AY, Alsubaie KM, Abu-Zaid A, Alzahrani FR, Sayed S, Pathak AK, Alqahtani KH
Head Neck 2021 Oct;43(10):3199-3213. Epub 2021 Jul 9 doi: 10.1002/hed.26798. PMID: 34240498
Lacas B, Carmel A, Landais C, Wong SJ, Licitra L, Tobias JS, Burtness B, Ghi MG, Cohen EEW, Grau C, Wolf G, Hitt R, Corvò R, Budach V, Kumar S, Laskar SG, Mazeron JJ, Zhong LP, Dobrowsky W, Ghadjar P, Fallai C, Zakotnik B, Sharma A, Bensadoun RJ, Ruo Redda MG, Racadot S, Fountzilas G, Brizel D, Rovea P, Argiris A, Nagy ZT, Lee JW, Fortpied C, Harris J, Bourhis J, Aupérin A, Blanchard P, Pignon JP; MACH-NC Collaborative Group
Radiother Oncol 2021 Mar;156:281-293. Epub 2021 Jan 27 doi: 10.1016/j.radonc.2021.01.013. PMID: 33515668Free PMC Article
Greco E, Simic T, Ringash J, Tomlinson G, Inamoto Y, Martino R
Int J Radiat Oncol Biol Phys 2018 Jun 1;101(2):421-444. Epub 2018 Feb 6 doi: 10.1016/j.ijrobp.2018.01.097. PMID: 29726363
Fukuhara H, Ino Y, Todo T
Cancer Sci 2016 Oct;107(10):1373-1379. Epub 2016 Sep 9 doi: 10.1111/cas.13027. PMID: 27486853Free PMC Article
Bossola M
Nutrients 2015 Jan 5;7(1):265-76. doi: 10.3390/nu7010265. PMID: 25569622Free PMC Article

Prognosis

Guo K, Xiao W, Chen X, Zhao Z, Lin Y, Chen G
Biomed Res Int 2021;2021:1738932. Epub 2021 Jul 14 doi: 10.1155/2021/1738932. PMID: 34337000Free PMC Article
Gupta S, Mortellaro C, Panda S, Rovati M, Giacomello MS, Colletti L, Greco Lucchina A, Del Fabbro M
J Biol Regul Homeost Agents 2021 Mar-Apr;35(2 Suppl. 1):53-65. doi: 10.23812/21-2supp1-5. PMID: 34281302
Hay AJ, Migliacci J, Karassawa Zanoni D, McGill M, Patel S, Ganly I
Cancer 2019 Oct 1;125(19):3354-3366. Epub 2019 Jun 7 doi: 10.1002/cncr.32208. PMID: 31174233Free PMC Article
Frowen J
Curr Opin Otolaryngol Head Neck Surg 2019 Jun;27(3):162-167. doi: 10.1097/MOO.0000000000000541. PMID: 30946062
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article

Clinical prediction guides

Long Q, Huang C, Meng Q, Peng J, Yao F, Du D, Wang X, Zhu W, Shi D, Xu X, Qi X, Deng W, Chen M, Li Y, Yang A
Front Immunol 2021;12:754818. Epub 2021 Oct 6 doi: 10.3389/fimmu.2021.754818. PMID: 34691075Free PMC Article
Bochtler T, Löffler H, Krämer A
Semin Diagn Pathol 2018 May;35(3):199-206. Epub 2017 Nov 26 doi: 10.1053/j.semdp.2017.11.013. PMID: 29203116
Moloney EC, Brunner M, Alexander AJ, Clark J
Head Neck 2015 Aug;37(8):1225-31. Epub 2014 Jul 11 doi: 10.1002/hed.23722. PMID: 24797251
Nelke KH, Pawlak W, Gerber H, Leszczyszyn J
Adv Clin Exp Med 2014 Nov-Dec;23(6):1019-27. doi: 10.17219/acem/37361. PMID: 25618131
Rivera F, García-Castaño A, Vega N, Vega-Villegas ME, Gutiérrez-Sanz L
Expert Rev Anticancer Ther 2009 Oct;9(10):1421-8. doi: 10.1586/era.09.113. PMID: 19828002

Recent systematic reviews

Mäkitie AA, Alabi RO, Orell H, Youssef O, Almangush A, Homma A, Takes RP, López F, de Bree R, Rodrigo JP, Ferlito A
Adv Ther 2022 Apr;39(4):1502-1523. Epub 2022 Feb 27 doi: 10.1007/s12325-022-02074-9. PMID: 35224702Free PMC Article
Banda KJ, Chu H, Kao CC, Voss J, Chiu HL, Chang PC, Chen R, Chou KR
Int J Nurs Stud 2021 Feb;114:103827. Epub 2020 Nov 11 doi: 10.1016/j.ijnurstu.2020.103827. PMID: 33352439
Dort JC, Farwell DG, Findlay M, Huber GF, Kerr P, Shea-Budgell MA, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J
JAMA Otolaryngol Head Neck Surg 2017 Mar 1;143(3):292-303. doi: 10.1001/jamaoto.2016.2981. PMID: 27737447
Gil-Montoya JA, Silvestre FJ, Barrios R, Silvestre-Rangil J
Med Oral Patol Oral Cir Bucal 2016 May 1;21(3):e355-66. doi: 10.4317/medoral.20969. PMID: 27031061Free PMC Article
Cohen EE, LaMonte SJ, Erb NL, Beckman KL, Sadeghi N, Hutcheson KA, Stubblefield MD, Abbott DM, Fisher PS, Stein KD, Lyman GH, Pratt-Chapman ML
CA Cancer J Clin 2016 May;66(3):203-39. Epub 2016 Mar 22 doi: 10.3322/caac.21343. PMID: 27002678

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...