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Coronary sinus enlargement

MedGen UID:
Concept ID:
Anatomical Abnormality
Synonyms: Coronary sinus dilatation; Enlarged coronary sinus
HPO: HP:0031298


Abnormal increase in size of the coronary sinus. [from HPO]

Term Hierarchy

Conditions with this feature

Cardiac-urogenital syndrome
MedGen UID:
Concept ID:
Disease or Syndrome
Cardiac-urogenital syndrome is characterized by partial anomalous pulmonary venous return in association with tracheal anomalies, pulmonary hypoplasia, congenital diaphragmatic hernia, thyroid fibrosis, thymic involution, cleft spleen, penoscrotal hypospadias, and cryptorchidism (Pinz et al., 2018).
Alzahrani-Kuwahara syndrome
MedGen UID:
Concept ID:
Disease or Syndrome
Alzahrani-Kuwahara syndrome (ALKUS) is an autosomal recessive neurodevelopmental syndrome characterized by global developmental delay with severely impaired intellectual function and poor or absent speech. Patients have poor overall growth and dysmorphic facial features. More variable findings include early-onset cataracts, hypotonia, congenital heart defects, lower limb spasticity, and hypospadias (summary by Alzahrani et al., 2020).
VISS syndrome
MedGen UID:
Concept ID:
Disease or Syndrome
VISS syndrome is a generalized connective tissue disorder characterized by early-onset thoracic aortic aneurysm and other connective tissue findings, such as aneurysm and tortuosity of other arteries, joint hypermobility, skin laxity, and hernias, as well as craniofacial dysmorphic features, structural cardiac defects, skeletal anomalies, and motor developmental delay (Van Gucht et al., 2021). Immune dysregulation has been observed in some patients (Ziegler et al., 2021).

Professional guidelines


Badhwar V, Rankin JS, Damiano RJ Jr, Gillinov AM, Bakaeen FG, Edgerton JR, Philpott JM, McCarthy PM, Bolling SF, Roberts HG, Thourani VH, Suri RM, Shemin RJ, Firestone S, Ad N
Ann Thorac Surg 2017 Jan;103(1):329-341. doi: 10.1016/j.athoracsur.2016.10.076. PMID: 28007240
Cohen M, Boiangiu C
Adv Ther 2011 Dec;28(12):1059-77. Epub 2011 Dec 12 doi: 10.1007/s12325-011-0086-1. PMID: 22170292
Braunlin EA, Harmatz PR, Scarpa M, Furlanetto B, Kampmann C, Loehr JP, Ponder KP, Roberts WC, Rosenfeld HM, Giugliani R
J Inherit Metab Dis 2011 Dec;34(6):1183-97. Epub 2011 Jul 9 doi: 10.1007/s10545-011-9359-8. PMID: 21744090Free PMC Article

Recent clinical studies


Marathe SP, Chávez M, Sleeper LA, Marx GR, Friedman K, Feins EN, Del Nido PJ, Baird CW
Semin Thorac Cardiovasc Surg 2022 Winter;34(4):1262-1272. Epub 2021 Oct 29 doi: 10.1053/j.semtcvs.2021.10.009. PMID: 34757016


Fellows KE Jr, Sigmann J, Stern AM, Bookstein JJ
Radiology 1970 Feb;94(2):347-9. doi: 10.1148/94.2.347. PMID: 5412802

Clinical prediction guides

Savu C, Petreanu C, Melinte A, Posea R, Balescu I, Iliescu L, Diaconu C, Galie N, Bacalbasa N
In Vivo 2020 Mar-Apr;34(2):935-941. doi: 10.21873/invivo.11861. PMID: 32111807Free PMC Article

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