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Abnormal glucose-6-phosphate dehydrogenase level in leukocytes

MedGen UID:
1632528
•Concept ID:
C4703669
•
Finding
Synonym: Abnormal G6PD level in leukocytes
 
HPO: HP:0410183

Definition

An anomaly in the level of glucose-6-phosphate dehydrogenase in leukocytes. [from HPO]

Recent clinical studies

Etiology

Differential expression of the proteome of myeloid dendritic cells in severe aplastic anemia.
Liu C, Sheng W, Fu R, Wang H, Li L, Liu H, Shao Z
Cell Immunol 2013 Sep-Oct;285(1-2):141-8. Epub 2013 Oct 10 doi: 10.1016/j.cellimm.2013.09.007. PMID: 24185280
Immunological and clinical aspects of kidney disease in endemic typhoid fever in Iran.
Khajehdehi P, Tastegar A, Kharazmi A
Q J Med 1984 Winter;53(209):101-7. PMID: 6608745
In vivo lability of glucose-6-phosphate dehydrogenase in GdA- and GdMediterranean deficiency.
Piomelli S, Corash LM, Davenport DD, Miraglia J, Amorosi EL
J Clin Invest 1968 Apr;47(4):940-8. doi: 10.1172/JCI105786. PMID: 5641629Free PMC Article

Diagnosis

Leukocyte glucose 6 phosphate dehydrogenase as prognostic indicator in ANLL and CML.
Devi GS, Prasad MH, Reddy PP, Rao DN
Indian J Exp Biol 1997 Feb;35(2):155-8. PMID: 9315224
Complete deficiency of leukocyte glucose-6-phosphate dehydrogenase with defective bactericidal activity.
Cooper MR, DeChatelet LR, McCall CE, LaVia MF, Spurr CL, Baehner RL
J Clin Invest 1972 Apr;51(4):769-78. doi: 10.1172/JCI106871. PMID: 4401271Free PMC Article

Therapy

Peripheral insensitivity to thyroid hormones in a euthyroid girl with goitre.
Mäenpää J, Liewendahl K
Arch Dis Child 1980 Mar;55(3):207-12. doi: 10.1136/adc.55.3.207. PMID: 6247978Free PMC Article

Prognosis

Leukocyte glucose 6 phosphate dehydrogenase as prognostic indicator in ANLL and CML.
Devi GS, Prasad MH, Reddy PP, Rao DN
Indian J Exp Biol 1997 Feb;35(2):155-8. PMID: 9315224
Clonal hematopoiesis and acquired thalassemia in common variable immunodeficiency.
Belickova M, Schroeder HW Jr, Guan YL, Brierre J, Berney S, Cooper MD, Prchal JT
Mol Med 1994 Nov;1(1):56-61. PMID: 8790601Free PMC Article

Clinical prediction guides

Complete deficiency of leukocyte glucose-6-phosphate dehydrogenase with defective bactericidal activity.
Cooper MR, DeChatelet LR, McCall CE, LaVia MF, Spurr CL, Baehner RL
J Clin Invest 1972 Apr;51(4):769-78. doi: 10.1172/JCI106871. PMID: 4401271Free PMC Article

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