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BRCA-Associated Ovarian Carcinoma

MedGen UID:
1635506
Concept ID:
C4688331
Neoplastic Process
Synonym: BRCA-Mutated Ovarian Carcinoma

Definition

Ovarian carcinoma caused by deleterious germline mutation in a gene of the BRCA family. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBRCA-Associated Ovarian Carcinoma

Professional guidelines

PubMed

Washington CR, Richardson DL, Moore KN
Future Oncol 2019 Oct;15(30):3435-3449. Epub 2019 Sep 3 doi: 10.2217/fon-2019-0271. PMID: 31478762
Lee MV, Katabathina VS, Bowerson ML, Mityul MI, Shetty AS, Elsayes KM, Balachandran A, Bhosale PR, McCullough AE, Menias CO
Radiographics 2017 Jul-Aug;37(4):1005-1023. Epub 2017 May 26 doi: 10.1148/rg.2017160144. PMID: 28548905
Bogliolo S, Cassani C, Dominoni M, Musacchi V, Venturini PL, Spinillo A, Ferrero S, Gardella B
Expert Opin Investig Drugs 2016;25(3):367-74. Epub 2016 Feb 16 doi: 10.1517/13543784.2016.1146677. PMID: 26807493

Recent clinical studies

Etiology

Bellcross CA
Obstet Gynecol Clin North Am 2022 Mar;49(1):117-147. doi: 10.1016/j.ogc.2021.11.005. PMID: 35168766
Lee MV, Katabathina VS, Bowerson ML, Mityul MI, Shetty AS, Elsayes KM, Balachandran A, Bhosale PR, McCullough AE, Menias CO
Radiographics 2017 Jul-Aug;37(4):1005-1023. Epub 2017 May 26 doi: 10.1148/rg.2017160144. PMID: 28548905
Daniels MS, Lu KH
Semin Oncol 2016 Oct;43(5):543-547. Epub 2016 Sep 20 doi: 10.1053/j.seminoncol.2016.08.005. PMID: 27899185
Shaw PA, Clarke BA
Surg Pathol Clin 2016 Jun;9(2):307-28. doi: 10.1016/j.path.2016.02.002. PMID: 27241111
Narod SA, Salmena L
Discov Med 2011 Nov;12(66):445-53. PMID: 22127115

Diagnosis

Bellcross CA
Obstet Gynecol Clin North Am 2022 Mar;49(1):117-147. doi: 10.1016/j.ogc.2021.11.005. PMID: 35168766
Washington CR, Richardson DL, Moore KN
Future Oncol 2019 Oct;15(30):3435-3449. Epub 2019 Sep 3 doi: 10.2217/fon-2019-0271. PMID: 31478762
Lee MV, Katabathina VS, Bowerson ML, Mityul MI, Shetty AS, Elsayes KM, Balachandran A, Bhosale PR, McCullough AE, Menias CO
Radiographics 2017 Jul-Aug;37(4):1005-1023. Epub 2017 May 26 doi: 10.1148/rg.2017160144. PMID: 28548905
Daniels MS, Lu KH
Semin Oncol 2016 Oct;43(5):543-547. Epub 2016 Sep 20 doi: 10.1053/j.seminoncol.2016.08.005. PMID: 27899185
Goulooze SC, Cohen AF, Rissmann R
Br J Clin Pharmacol 2016 Jan;81(1):171-3. Epub 2015 Oct 24 doi: 10.1111/bcp.12761. PMID: 26344419Free PMC Article

Therapy

Desai C, Pathak A, Limaye S, Maniar V, Joshi A
Indian J Cancer 2022 Mar;59(Supplement):S119-S129. doi: 10.4103/ijc.IJC_53_21. PMID: 35343196
Washington CR, Richardson DL, Moore KN
Future Oncol 2019 Oct;15(30):3435-3449. Epub 2019 Sep 3 doi: 10.2217/fon-2019-0271. PMID: 31478762
Bogliolo S, Cassani C, Dominoni M, Musacchi V, Venturini PL, Spinillo A, Ferrero S, Gardella B
Expert Opin Investig Drugs 2016;25(3):367-74. Epub 2016 Feb 16 doi: 10.1517/13543784.2016.1146677. PMID: 26807493
Goulooze SC, Cohen AF, Rissmann R
Br J Clin Pharmacol 2016 Jan;81(1):171-3. Epub 2015 Oct 24 doi: 10.1111/bcp.12761. PMID: 26344419Free PMC Article
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, Mortimer P, Swaisland H, Lau A, O'Connor MJ, Ashworth A, Carmichael J, Kaye SB, Schellens JH, de Bono JS
N Engl J Med 2009 Jul 9;361(2):123-34. Epub 2009 Jun 24 doi: 10.1056/NEJMoa0900212. PMID: 19553641

Prognosis

Pallonen TA, Lempiäinen SMM, Joutsiniemi TK, Aaltonen RI, Pohjola PE, Kankuri-Tammilehto MK
Sci Rep 2022 Apr 25;12(1):6704. doi: 10.1038/s41598-022-10519-y. PMID: 35469032Free PMC Article
Bellcross CA
Obstet Gynecol Clin North Am 2022 Mar;49(1):117-147. doi: 10.1016/j.ogc.2021.11.005. PMID: 35168766
Tung NM, Garber JE
Br J Cancer 2018 Jul;119(2):141-152. Epub 2018 Jun 5 doi: 10.1038/s41416-018-0127-5. PMID: 29867226Free PMC Article
Lee MV, Katabathina VS, Bowerson ML, Mityul MI, Shetty AS, Elsayes KM, Balachandran A, Bhosale PR, McCullough AE, Menias CO
Radiographics 2017 Jul-Aug;37(4):1005-1023. Epub 2017 May 26 doi: 10.1148/rg.2017160144. PMID: 28548905
Girolimetti G, Perrone AM, Santini D, Barbieri E, Guerra F, Ferrari S, Zamagni C, De Iaco P, Gasparre G, Turchetti D
Biomed Res Int 2014;2014:787143. Epub 2014 Jul 22 doi: 10.1155/2014/787143. PMID: 25136623Free PMC Article

Clinical prediction guides

Pallonen TA, Lempiäinen SMM, Joutsiniemi TK, Aaltonen RI, Pohjola PE, Kankuri-Tammilehto MK
Sci Rep 2022 Apr 25;12(1):6704. doi: 10.1038/s41598-022-10519-y. PMID: 35469032Free PMC Article
Bellcross CA
Obstet Gynecol Clin North Am 2022 Mar;49(1):117-147. doi: 10.1016/j.ogc.2021.11.005. PMID: 35168766
Tung NM, Garber JE
Br J Cancer 2018 Jul;119(2):141-152. Epub 2018 Jun 5 doi: 10.1038/s41416-018-0127-5. PMID: 29867226Free PMC Article
Girolimetti G, Perrone AM, Santini D, Barbieri E, Guerra F, Ferrari S, Zamagni C, De Iaco P, Gasparre G, Turchetti D
Biomed Res Int 2014;2014:787143. Epub 2014 Jul 22 doi: 10.1155/2014/787143. PMID: 25136623Free PMC Article
Vollebergh MA, Jonkers J, Linn SC
Cell Mol Life Sci 2012 Jan;69(2):223-45. Epub 2011 Sep 16 doi: 10.1007/s00018-011-0809-0. PMID: 21922196

Supplemental Content

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