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Medial rectus muscle weakness

MedGen UID:
1635974
•Concept ID:
C4703522
•
Pathologic Function
HPO: HP:0031753

Definition

Decreased strength of the medial rectus muscle. [from HPO]

Professional guidelines

PubMed

The efficacy of botulinum neurotoxin A for the treatment of complete and partially recovered chronic sixth nerve palsy.
Repka MX, Lam GC, Morrison NA
J Pediatr Ophthalmol Strabismus 1994 Mar-Apr;31(2):79-83; discussion 84. doi: 10.3928/0191-3913-19940301-04. PMID: 8014791
The diagnosis and treatment of abduction deficiencies.
Metz HS
Ann Ophthalmol 1976 Jun;8(6):683-93. PMID: 937951

Recent clinical studies

Etiology

Muscle weakness has a limited effect on motor control of gait in Duchenne muscular dystrophy.
Vandekerckhove I, De Beukelaer N, Van den Hauwe M, Shuman BR, Steele KM, Van Campenhout A, Goemans N, Desloovere K, Goudriaan M
PLoS One 2020;15(9):e0238445. Epub 2020 Sep 2 doi: 10.1371/journal.pone.0238445. PMID: 32877421Free PMC Article
Convergence Weakness with Intact Medial Rectus Function in Proptosis due to Orbital Tumors.
Salunke P, Karthigeyan M, Praneeth K, Kaur S, Takkar A
Neurol India 2020 Jul-Aug;68(4):840-842. doi: 10.4103/0028-3886.293479. PMID: 32859825
Sex- and osteoarthritis-related differences in muscle co-activation during weight-bearing tasks.
Smith SL, Woodburn J, Steultjens MPM
Gait Posture 2020 Jun;79:117-125. Epub 2020 Apr 27 doi: 10.1016/j.gaitpost.2020.04.019. PMID: 32402893
Transposition procedures in Duane retraction syndrome.
Doyle JJ, Hunter DG
J AAPOS 2019 Feb;23(1):5-14. Epub 2018 Dec 23 doi: 10.1016/j.jaapos.2018.10.008. PMID: 30586616
Limb muscle quality and quantity in elderly adults with dynapenia but not sarcopenia: An ultrasound imaging study.
Chang KV, Wu WT, Huang KC, Jan WH, Han DS
Exp Gerontol 2018 Jul 15;108:54-61. Epub 2018 Mar 28 doi: 10.1016/j.exger.2018.03.019. PMID: 29604401

Diagnosis

Management of acute acquired comitant esotropia in children.
Dragomir MS, Merticariu M, Merticariu CI
Rom J Ophthalmol 2023 Jan-Mar;67(1):87-91. doi: 10.22336/rjo.2023.16. PMID: 37089805Free PMC Article
Sonoelastography of the trunk and lower extremity muscles in a case of Duchenne muscular dystrophy.
Cornelson SM, Ruff AN, Perillat M, Kettner NW
J Ultrasound 2021 Sep;24(3):343-347. Epub 2019 Jun 29 doi: 10.1007/s40477-019-00394-1. PMID: 31256365Free PMC Article
Immune checkpoint inhibitors (ICIs)-related ocular myositis.
Garibaldi M, Calabrò F, Merlonghi G, Pugliese S, Ceccanti M, Cristiano L, Tartaglione T, Petrucci A
Neuromuscul Disord 2020 May;30(5):420-423. Epub 2020 Feb 26 doi: 10.1016/j.nmd.2020.02.013. PMID: 32387281
Limb muscle quality and quantity in elderly adults with dynapenia but not sarcopenia: An ultrasound imaging study.
Chang KV, Wu WT, Huang KC, Jan WH, Han DS
Exp Gerontol 2018 Jul 15;108:54-61. Epub 2018 Mar 28 doi: 10.1016/j.exger.2018.03.019. PMID: 29604401
Magnetic resonance imaging of leg muscles in patients with myotonic dystrophies.
Peric S, Maksimovic R, Banko B, Durdic M, Bjelica B, Bozovic I, Balcik Y, Pesovic J, Savic-Pavicevic D, Rakocevic-Stojanovic V
J Neurol 2017 Sep;264(9):1899-1908. Epub 2017 Jul 29 doi: 10.1007/s00415-017-8574-0. PMID: 28756605

Therapy

Immune checkpoint inhibitors (ICIs)-related ocular myositis.
Garibaldi M, Calabrò F, Merlonghi G, Pugliese S, Ceccanti M, Cristiano L, Tartaglione T, Petrucci A
Neuromuscul Disord 2020 May;30(5):420-423. Epub 2020 Feb 26 doi: 10.1016/j.nmd.2020.02.013. PMID: 32387281
Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults.
Lee SH, Lee HJ, Chang WH, Choi BO, Lee J, Kim J, Ryu GH, Kim YH
J Neuroeng Rehabil 2017 Nov 28;14(1):123. doi: 10.1186/s12984-017-0333-z. PMID: 29183379Free PMC Article
Facial nerve injury during external dacryocystorhinostomy.
Vagefi MR, Winn BJ, Lin CC, Sires BS, LauKaitis SJ, Anderson RL, McCann JD
Ophthalmology 2009 Mar;116(3):585-90. Epub 2008 Dec 16 doi: 10.1016/j.ophtha.2008.09.050. PMID: 19091406
Botulinum toxin injection for postoperative diplopia testing in adult strabismus.
Khan J, Kumar I, Marsh IB
J AAPOS 2008 Feb;12(1):46-8. Epub 2007 Oct 25 doi: 10.1016/j.jaapos.2007.07.006. PMID: 17964210
Breast reconstruction with superficial inferior epigastric artery flaps: a prospective comparison with TRAM and DIEP flaps.
Chevray PM
Plast Reconstr Surg 2004 Oct;114(5):1077-83; discussion 1084-5. doi: 10.1097/01.prs.0000135328.88101.53. PMID: 15457015

Prognosis

Sonographic evaluations of the skeletal muscles in patients with Pompe disease.
Chiu YH, Liao CL, Chien YH, Wu CH, Özçakar L
Eur J Paediatr Neurol 2023 Jan;42:22-27. Epub 2022 Dec 6 doi: 10.1016/j.ejpn.2022.12.002. PMID: 36508847
Sex- and osteoarthritis-related differences in muscle co-activation during weight-bearing tasks.
Smith SL, Woodburn J, Steultjens MPM
Gait Posture 2020 Jun;79:117-125. Epub 2020 Apr 27 doi: 10.1016/j.gaitpost.2020.04.019. PMID: 32402893
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Less invasive rotational acetabular osteotomy for hip dysplasia.
Maruyama M, Wakabayashi S, Tensho K
Clin Orthop Relat Res 2013 Apr;471(4):1263-70. Epub 2012 Sep 25 doi: 10.1007/s11999-012-2599-6. PMID: 23008024Free PMC Article
Facial nerve injury during external dacryocystorhinostomy.
Vagefi MR, Winn BJ, Lin CC, Sires BS, LauKaitis SJ, Anderson RL, McCann JD
Ophthalmology 2009 Mar;116(3):585-90. Epub 2008 Dec 16 doi: 10.1016/j.ophtha.2008.09.050. PMID: 19091406

Clinical prediction guides

Sonographic evaluations of the skeletal muscles in patients with Pompe disease.
Chiu YH, Liao CL, Chien YH, Wu CH, Özçakar L
Eur J Paediatr Neurol 2023 Jan;42:22-27. Epub 2022 Dec 6 doi: 10.1016/j.ejpn.2022.12.002. PMID: 36508847
Sex- and osteoarthritis-related differences in muscle co-activation during weight-bearing tasks.
Smith SL, Woodburn J, Steultjens MPM
Gait Posture 2020 Jun;79:117-125. Epub 2020 Apr 27 doi: 10.1016/j.gaitpost.2020.04.019. PMID: 32402893
Immune checkpoint inhibitors (ICIs)-related ocular myositis.
Garibaldi M, Calabrò F, Merlonghi G, Pugliese S, Ceccanti M, Cristiano L, Tartaglione T, Petrucci A
Neuromuscul Disord 2020 May;30(5):420-423. Epub 2020 Feb 26 doi: 10.1016/j.nmd.2020.02.013. PMID: 32387281
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Gait performance and foot pressure distribution during wearable robot-assisted gait in elderly adults.
Lee SH, Lee HJ, Chang WH, Choi BO, Lee J, Kim J, Ryu GH, Kim YH
J Neuroeng Rehabil 2017 Nov 28;14(1):123. doi: 10.1186/s12984-017-0333-z. PMID: 29183379Free PMC Article

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