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Abnormal medial rectus muscle physiology

MedGen UID:
1643941
Concept ID:
C4703413
Pathologic Function
HPO: HP:0025606

Definition

A functional anomaly of the medial rectus muscle, an extraocular muscle that is innervated by the inferior division of the oculomotor nerve and whose sole action is the adduction of the eyeball. [from HPO]

Recent clinical studies

Etiology

Warkad VU, Hunter DG, Dagi AF, Mackinnon S, Kazlas MA, Heidary G, Staffa SJ, Dagi LR
Am J Ophthalmol 2022 May;237:83-90. Epub 2021 Nov 13 doi: 10.1016/j.ajo.2021.11.006. PMID: 34780796
Fouad HM, Awadein A, Youssef AA, Saeed H, Shousha SM
Semin Ophthalmol 2020 Jan 2;35(1):66-77. Epub 2020 Mar 4 doi: 10.1080/08820538.2020.1730915. PMID: 32126862
Hao R, Suh SY, Le A, Demer JL
Ophthalmology 2016 Sep;123(9):2004-12. Epub 2016 Jul 19 doi: 10.1016/j.ophtha.2016.05.053. PMID: 27448831Free PMC Article
Jung JH, Leske DA, Holmes JM
J AAPOS 2016 Jun;20(3):197-200. Epub 2016 May 6 doi: 10.1016/j.jaapos.2016.02.008. PMID: 27164430Free PMC Article
Clark RA
Middle East Afr J Ophthalmol 2015 Jul-Sep;22(3):279-85. doi: 10.4103/0974-9233.159698. PMID: 26180464Free PMC Article

Diagnosis

Warkad VU, Hunter DG, Dagi AF, Mackinnon S, Kazlas MA, Heidary G, Staffa SJ, Dagi LR
Am J Ophthalmol 2022 May;237:83-90. Epub 2021 Nov 13 doi: 10.1016/j.ajo.2021.11.006. PMID: 34780796
Hatt SR, Leske DA, Jung JH, Holmes JM
Ophthalmology 2017 Jun;124(6):828-834. Epub 2017 Feb 24 doi: 10.1016/j.ophtha.2017.01.031. PMID: 28238457Free PMC Article
Gilbert AL, Hunter DG
J AAPOS 2017 Apr;21(2):165-167. Epub 2016 Dec 10 doi: 10.1016/j.jaapos.2016.09.017. PMID: 27965142
Clark RA
Middle East Afr J Ophthalmol 2015 Jul-Sep;22(3):279-85. doi: 10.4103/0974-9233.159698. PMID: 26180464Free PMC Article
Kim JH, Hwang JM
Optom Vis Sci 2009 Dec;86(12):1386-8. doi: 10.1097/OPX.0b013e3181be9db3. PMID: 19826317

Therapy

Shen T, Kang Y, Lin X, Wu H, Yan J
Int Ophthalmol 2022 Oct;42(10):2965-2972. Epub 2022 Jan 27 doi: 10.1007/s10792-021-02173-6. PMID: 35083599
Lee SH, Lee HJ, Chang WH, Choi BO, Lee J, Kim J, Ryu GH, Kim YH
J Neuroeng Rehabil 2017 Nov 28;14(1):123. doi: 10.1186/s12984-017-0333-z. PMID: 29183379Free PMC Article
Laria C, Merino-Suárez ML, Piñero DP, Gómez-Hurtado A, Pérez-Cambrodí RJ
Semin Ophthalmol 2015;30(5-6):393-6. Epub 2014 May 8 doi: 10.3109/08820538.2014.912337. PMID: 24809739
Velez FG, Oltra E, Isenberg SJ, Pineles SL
J AAPOS 2014 Oct;18(5):457-60. Epub 2014 Sep 27 doi: 10.1016/j.jaapos.2014.06.008. PMID: 25266834Free PMC Article
Vagefi MR, Winn BJ, Lin CC, Sires BS, LauKaitis SJ, Anderson RL, McCann JD
Ophthalmology 2009 Mar;116(3):585-90. Epub 2008 Dec 16 doi: 10.1016/j.ophtha.2008.09.050. PMID: 19091406

Prognosis

Shen T, Kang Y, Lin X, Wu H, Yan J
Int Ophthalmol 2022 Oct;42(10):2965-2972. Epub 2022 Jan 27 doi: 10.1007/s10792-021-02173-6. PMID: 35083599
Fouad HM, Awadein A, Youssef AA, Saeed H, Shousha SM
Semin Ophthalmol 2020 Jan 2;35(1):66-77. Epub 2020 Mar 4 doi: 10.1080/08820538.2020.1730915. PMID: 32126862
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Sawada M, Hikoya A, Negishi T, Hotta Y, Sato M
Jpn J Ophthalmol 2015 Sep;59(5):335-40. Epub 2015 Aug 6 doi: 10.1007/s10384-015-0395-z. PMID: 26243693
Frohman TC, Galetta S, Fox R, Solomon D, Straumann D, Filippi M, Zee D, Frohman EM
Neurology 2008 Apr 22;70(17):e57-67. doi: 10.1212/01.wnl.0000310640.37810.b3. PMID: 18427066

Clinical prediction guides

Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Reissman ME, Gordon KE, Dhaher YY
J Biomech 2018 Jan 23;67:129-136. Epub 2017 Dec 6 doi: 10.1016/j.jbiomech.2017.11.031. PMID: 29248191
Ku PX, Abu Osman NA, Wan Abas WAB
J Biomech 2016 Dec 8;49(16):3943-3948. Epub 2016 Nov 10 doi: 10.1016/j.jbiomech.2016.11.006. PMID: 27865478
Clark RA
Middle East Afr J Ophthalmol 2015 Jul-Sep;22(3):279-85. doi: 10.4103/0974-9233.159698. PMID: 26180464Free PMC Article
Farvardin M, Rad AH, Ashrafzadeh A
J AAPOS 2009 Aug;13(4):339-42. doi: 10.1016/j.jaapos.2009.04.014. PMID: 19683185

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