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B Lymphoblastic Lymphoma

MedGen UID:
163608
Concept ID:
C0855146
Neoplastic Process
Synonyms: B-Lymphoblastic Lymphoma; Precursor B-cell lymphoblastic lymphoma; Precursor B-Lymphoblastic Lymphoma
SNOMED CT: Precursor B-cell lymphoblastic lymphoma (128807009)

Definition

An uncommon type of lymphoma. It constitutes approximately 10% of cases of lymphoblastic lymphoma. Approximately 75% of cases reported in a literature review involved patients who were less than 18 years of age. The most commonly affected sites are the skin, bone, soft tissue, and lymph nodes. It has a high remission rate with a median survival of approximately 60 months. (WHO, 2001) [from NCI]

Professional guidelines

PubMed

Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Chang MH, Kim SJ, Kim K, Oh SY, Lee DH, Huh J, Ko YH, Choi CW, Yang DH, Won JH, Kim WS, Suh C
Leuk Lymphoma 2009 Jul;50(7):1119-25. doi: 10.1080/10428190902926999. PMID: 19557632
Cheng AL, Su IJ, Tien HF, Wang CC, Chen YC, Wang CH
Cancer 1994 Feb 1;73(3):706-10. doi: 10.1002/1097-0142(19940201)73:3<706::aid-cncr2820730334>3.0.co;2-u. PMID: 7507799

Recent clinical studies

Etiology

Duffield AS, Mullighan CG, Borowitz MJ
Virchows Arch 2023 Jan;482(1):11-26. Epub 2022 Nov 24 doi: 10.1007/s00428-022-03448-8. PMID: 36422706Free PMC Article
Myers RM, Li Y, Barz Leahy A, Barrett DM, Teachey DT, Callahan C, Fasano CC, Rheingold SR, DiNofia A, Wray L, Aplenc R, Baniewicz D, Liu H, Shaw PA, Pequignot E, Getz KD, Brogdon JL, Fesnak AD, Siegel DL, Davis MM, Bartoszek C, Lacey SF, Hexner EO, Chew A, Wertheim GB, Levine BL, June CH, Grupp SA, Maude SL
J Clin Oncol 2021 Sep 20;39(27):3044-3055. Epub 2021 Jun 22 doi: 10.1200/JCO.20.03458. PMID: 34156874Free PMC Article
Knez V, Bao L, Carstens B, Liang X
Leuk Lymphoma 2020 Sep;61(9):2129-2135. Epub 2020 May 19 doi: 10.1080/10428194.2020.1761970. PMID: 32427530
Said JW
Mod Pathol 2013 Jan;26 Suppl 1(0 1):S42-56. Epub 2012 Nov 16 doi: 10.1038/modpathol.2012.178. PMID: 23154748Free PMC Article
de Jong D, de Boer JP
Leuk Lymphoma 2009 Sep;50(9):1406-11. doi: 10.1080/10428190903093815. PMID: 19606378

Diagnosis

Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Duffield AS, Mullighan CG, Borowitz MJ
Virchows Arch 2023 Jan;482(1):11-26. Epub 2022 Nov 24 doi: 10.1007/s00428-022-03448-8. PMID: 36422706Free PMC Article
Symeonidis NG, Stavrati KE, Pavlidis ET, Psarras KK, Martzivanou E, Kofinas A, Pavlidis TE
Am Surg 2023 Apr;89(4):1280-1282. Epub 2021 Feb 25 doi: 10.1177/0003134821998679. PMID: 33629871
Fujimoto A, Ikejiri F, Arakawa F, Ito S, Okada Y, Takahashi F, Matsuda S, Okada T, Inoue M, Takahashi T, Miyake T, Maruyama R, Ohshima K, Suzumiya J, Suzuki R
Am J Clin Pathol 2021 Feb 4;155(2):308-317. doi: 10.1093/ajcp/aqaa126. PMID: 32915189
Abdul Jalil D, Raja Sabudin RZA, Tang YL, Masir N
Malays J Pathol 2020 Aug;42(2):273-276. PMID: 32860381

Therapy

Das M, Tsuchiya KD, Bohling SD, Davis B, Hwang S, Gardner RA, Chisholm KM
Pediatr Dev Pathol 2024 Mar-Apr;27(2):193-197. Epub 2023 Nov 30 doi: 10.1177/10935266231212337. PMID: 38032739
Myers RM, Li Y, Barz Leahy A, Barrett DM, Teachey DT, Callahan C, Fasano CC, Rheingold SR, DiNofia A, Wray L, Aplenc R, Baniewicz D, Liu H, Shaw PA, Pequignot E, Getz KD, Brogdon JL, Fesnak AD, Siegel DL, Davis MM, Bartoszek C, Lacey SF, Hexner EO, Chew A, Wertheim GB, Levine BL, June CH, Grupp SA, Maude SL
J Clin Oncol 2021 Sep 20;39(27):3044-3055. Epub 2021 Jun 22 doi: 10.1200/JCO.20.03458. PMID: 34156874Free PMC Article
Li X, Cao W, Zhang S, Li L, Li Y, Jiang Z, Wan D, Yu J
Medicine (Baltimore) 2021 Jun 11;100(23):e26323. doi: 10.1097/MD.0000000000026323. PMID: 34115047Free PMC Article
Yamada C, Shimomura Y, Kamijyo K, Kanda-Kato M, Yoshioka S, Yamashita D, Ishikawa T
Intern Med 2021 Oct 1;60(19):3149-3153. Epub 2021 Apr 5 doi: 10.2169/internalmedicine.7066-21. PMID: 33814500Free PMC Article
Sakarou M, Eisele L, Dührsen U, Hüttmann A
Eur J Haematol 2019 Mar;102(3):241-250. Epub 2019 Jan 20 doi: 10.1111/ejh.13199. PMID: 30471148

Prognosis

Devine KJ, Fries C, Hermiston M, Wistinghausen B
Pediatr Blood Cancer 2023 Aug;70(8):e30401. Epub 2023 May 9 doi: 10.1002/pbc.30401. PMID: 37158503
Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Abdul Jalil D, Raja Sabudin RZA, Tang YL, Masir N
Malays J Pathol 2020 Aug;42(2):273-276. PMID: 32860381
Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR
Pediatr Blood Cancer 2017 Jul;64(7) Epub 2016 Dec 13 doi: 10.1002/pbc.26363. PMID: 27957801
de Jong D, de Boer JP
Leuk Lymphoma 2009 Sep;50(9):1406-11. doi: 10.1080/10428190903093815. PMID: 19606378

Clinical prediction guides

Devine KJ, Trivedi H, Reilly AF
J Pediatr Hematol Oncol 2024 Apr 1;46(3):e254-e258. Epub 2024 Feb 16 doi: 10.1097/MPH.0000000000002828. PMID: 38408123Free PMC Article
Devine KJ, Fries C, Hermiston M, Wistinghausen B
Pediatr Blood Cancer 2023 Aug;70(8):e30401. Epub 2023 May 9 doi: 10.1002/pbc.30401. PMID: 37158503
Knez V, Bao L, Carstens B, Liang X
Leuk Lymphoma 2020 Sep;61(9):2129-2135. Epub 2020 May 19 doi: 10.1080/10428194.2020.1761970. PMID: 32427530
Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR
Pediatr Blood Cancer 2017 Jul;64(7) Epub 2016 Dec 13 doi: 10.1002/pbc.26363. PMID: 27957801
de Jong D, de Boer JP
Leuk Lymphoma 2009 Sep;50(9):1406-11. doi: 10.1080/10428190903093815. PMID: 19606378

Recent systematic reviews

Croci DM, Gamboa NT, Osman AEG, Maese L, Mazur M, Bisson EF, Dailey AT
Clin Neurol Neurosurg 2022 Jan;212:107064. Epub 2021 Nov 24 doi: 10.1016/j.clineuro.2021.107064. PMID: 34871993

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