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Refractory B Acute Lymphoblastic Leukemia

MedGen UID:
1636080
Concept ID:
C4684834
Neoplastic Process
Synonym: Refractory B-Cell Acute Lymphoblastic Leukemia

Definition

B-acute lymphoblastic leukemia that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory B Acute Lymphoblastic Leukemia

Professional guidelines

PubMed

Dholaria BR, Bachmeier CA, Locke F
BioDrugs 2019 Feb;33(1):45-60. doi: 10.1007/s40259-018-0324-z. PMID: 30560413Free PMC Article
Papayannidis C, Derenzini E, Iacobucci I, Curti A, Paolini S, Cilloni D, Baccarani M, Martinelli G
Am J Hematol 2009 Dec;84(12):849-50. doi: 10.1002/ajh.21548. PMID: 19844989

Recent clinical studies

Etiology

Wang T, Tang Y, Cai J, Wan X, Hu S, Lu X, Xie Z, Qiao X, Jiang H, Shao J, Yang F, Ren H, Cao Q, Qian J, Zhang J, An K, Wang J, Luo C, Liang H, Miao Y, Ma Y, Wang X, Ding L, Song L, He H, Shi W, Xiao P, Yang X, Yang J, Li W, Zhu Y, Wang N, Gu L, Chen Q, Tang J, Yang JJ, Cheng C, Leung W, Chen J, Lu J, Li B, Pui CH
J Clin Oncol 2023 Mar 20;41(9):1670-1683. Epub 2022 Nov 8 doi: 10.1200/JCO.22.01214. PMID: 36346962Free PMC Article
Leahy AB, Devine KJ, Li Y, Liu H, Myers R, DiNofia A, Wray L, Rheingold SR, Callahan C, Baniewicz D, Patino M, Newman H, Hunger SP, Grupp SA, Barrett DM, Maude SL
Blood 2022 Apr 7;139(14):2173-2185. doi: 10.1182/blood.2021012727. PMID: 34871373Free PMC Article
Contreras CF, Higham CS, Behnert A, Kim K, Stieglitz E, Tasian SK
Pediatr Blood Cancer 2021 Jan;68(1):e28718. Epub 2020 Oct 24 doi: 10.1002/pbc.28718. PMID: 33098744Free PMC Article

Diagnosis

Lamble AJ, Tasian SK
Blood Adv 2019 Nov 26;3(22):3750-3758. doi: 10.1182/bloodadvances.2019000357. PMID: 31770440Free PMC Article

Therapy

Wang T, Tang Y, Cai J, Wan X, Hu S, Lu X, Xie Z, Qiao X, Jiang H, Shao J, Yang F, Ren H, Cao Q, Qian J, Zhang J, An K, Wang J, Luo C, Liang H, Miao Y, Ma Y, Wang X, Ding L, Song L, He H, Shi W, Xiao P, Yang X, Yang J, Li W, Zhu Y, Wang N, Gu L, Chen Q, Tang J, Yang JJ, Cheng C, Leung W, Chen J, Lu J, Li B, Pui CH
J Clin Oncol 2023 Mar 20;41(9):1670-1683. Epub 2022 Nov 8 doi: 10.1200/JCO.22.01214. PMID: 36346962Free PMC Article
Leahy AB, Devine KJ, Li Y, Liu H, Myers R, DiNofia A, Wray L, Rheingold SR, Callahan C, Baniewicz D, Patino M, Newman H, Hunger SP, Grupp SA, Barrett DM, Maude SL
Blood 2022 Apr 7;139(14):2173-2185. doi: 10.1182/blood.2021012727. PMID: 34871373Free PMC Article
Contreras CF, Higham CS, Behnert A, Kim K, Stieglitz E, Tasian SK
Pediatr Blood Cancer 2021 Jan;68(1):e28718. Epub 2020 Oct 24 doi: 10.1002/pbc.28718. PMID: 33098744Free PMC Article
Wilke AC, Gökbuget N
Expert Opin Drug Saf 2017 Oct;16(10):1191-1202. Epub 2017 Aug 20 doi: 10.1080/14740338.2017.1338270. PMID: 28825327
Stieglmaier J, Benjamin J, Nagorsen D
Expert Opin Biol Ther 2015;15(8):1093-9. Epub 2015 May 13 doi: 10.1517/14712598.2015.1041373. PMID: 25971805

Prognosis

Contreras CF, Higham CS, Behnert A, Kim K, Stieglitz E, Tasian SK
Pediatr Blood Cancer 2021 Jan;68(1):e28718. Epub 2020 Oct 24 doi: 10.1002/pbc.28718. PMID: 33098744Free PMC Article
Dholaria BR, Bachmeier CA, Locke F
BioDrugs 2019 Feb;33(1):45-60. doi: 10.1007/s40259-018-0324-z. PMID: 30560413Free PMC Article

Clinical prediction guides

Dholaria BR, Bachmeier CA, Locke F
BioDrugs 2019 Feb;33(1):45-60. doi: 10.1007/s40259-018-0324-z. PMID: 30560413Free PMC Article

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    Practice guidelines

    • PubMed
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    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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