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Acquired cystic disease-associated renal cell carcinoma

MedGen UID:
1644241
Concept ID:
C4707179
Neoplastic Process
Synonyms: Acquired cystic disease associated renal cell carcinoma; Acquired Cystic Disease-Associated Renal Cell Carcinoma; acquired cystic disease-associated renal cell carcinoma
SNOMED CT: Acquired cystic disease associated renal cell carcinoma (764856008)
 
Monarch Initiative: MONDO:0018449
Orphanet: ORPHA404514

Definition

A rare subtype of renal cell carcinoma, occurring in the context of end-stage kidney disease and acquired cystic kidney disease, characterised by a usually well circumscribed, solid, multifocal, bilateral tumour with inter or intracellular micro lumen formation (leading to cribiform architecture). Tumours are often diagnosed incidentally in early stages, although complications caused by renal cysts (dull flank or abdominal pain, fever) or renal parenchymal bleeding may mask the underlying neoplastic process. Most have an indolent behaviour. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcquired cystic disease-associated renal cell carcinoma

Professional guidelines

PubMed

Delahunt B, Srigley JR, Montironi R, Egevad L
Urology 2014 May;83(5):969-74. Epub 2014 Mar 22 doi: 10.1016/j.urology.2014.02.004. PMID: 24661331

Recent clinical studies

Etiology

Carnahan MB, Kunzelman J, Kawashima A, Patel BN, Menias CO, Fananapazir G
Abdom Radiol (NY) 2022 Aug;47(8):2858-2866. Epub 2022 Jun 8 doi: 10.1007/s00261-022-03566-6. PMID: 35674787
Chrabańska M, Ryszawy J, Drozdzowska B
Indian J Cancer 2021 Oct-Dec;58(4):608-614. doi: 10.4103/ijc.IJC_720_20. PMID: 34975102
Kojima F, Gandhi JS, Matsuzaki I, Iba A, Collier S, Yoshikawa T, Kinoshita Y, Warigaya K, Fujimoto M, Kuroda N, Morii E, Hara I, Murata SI, Amin MB
Am J Surg Pathol 2020 Aug;44(8):1031-1039. doi: 10.1097/PAS.0000000000001482. PMID: 32271189
Tsuzuki T, Iwata H, Murase Y, Takahara T, Ohashi A
Int J Urol 2018 Sep;25(9):780-786. Epub 2018 Jul 31 doi: 10.1111/iju.13759. PMID: 30066367
Przybycin CG, Harper HL, Reynolds JP, Magi-Galluzzi C, Nguyen JK, Wu A, Sangoi AR, Liu PS, Umar S, Mehra R, Zhang X, Cox RM, McKenney JK
Am J Surg Pathol 2018 Sep;42(9):1156-1165. doi: 10.1097/PAS.0000000000001091. PMID: 29851703

Diagnosis

Tsuzuki T, Iwata H, Murase Y, Takahara T, Ohashi A
Int J Urol 2018 Sep;25(9):780-786. Epub 2018 Jul 31 doi: 10.1111/iju.13759. PMID: 30066367
Sun Y, Argani P, Tickoo SK, Epstein JI
Am J Surg Pathol 2018 Oct;42(10):1396-1401. doi: 10.1097/PAS.0000000000001124. PMID: 30001236
Foshat M, Eyzaguirre E
Arch Pathol Lab Med 2017 Apr;141(4):600-606. doi: 10.5858/arpa.2016-0123-RS. PMID: 28353376
Ahn S, Kwon GY, Cho YM, Jun SY, Choi C, Kim HJ, Park YW, Park WS, Shim JW
Med Mol Morphol 2013 Dec;46(4):225-32. Epub 2013 Mar 8 doi: 10.1007/s00795-013-0028-x. PMID: 23471757
Kuroda N, Ohe C, Mikami S, Hes O, Michal M, Brunelli M, Martignoni G, Sato Y, Yoshino T, Kakehi Y, Shuin T, Lee GH
Histol Histopathol 2011 Sep;26(9):1215-8. doi: 10.14670/HH-26.1215. PMID: 21751153

Therapy

Kondo T, Sasa N, Yamada H, Takagi T, Iizuka J, Kobayashi H, Yoshida K, Fukuda H, Ishihara H, Tanabe K, Tsuzuki T
Pathol Int 2018 Oct;68(10):543-549. Epub 2018 Sep 6 doi: 10.1111/pin.12718. PMID: 30187581
Pan CC, Chen YJ, Chang LC, Chang YH, Ho DM
Histopathology 2009 Aug;55(2):145-53. doi: 10.1111/j.1365-2559.2009.03361.x. PMID: 19694821

Prognosis

Duong NX, Le MK, Nguyen TT, Nguyen DD, Vuong HG, Kondo T, Mitsui T
Clin Genitourin Cancer 2024 Jun;22(3):102050. Epub 2024 Feb 14 doi: 10.1016/j.clgc.2024.02.001. PMID: 38502982
Tsuzuki T, Iwata H, Murase Y, Takahara T, Ohashi A
Int J Urol 2018 Sep;25(9):780-786. Epub 2018 Jul 31 doi: 10.1111/iju.13759. PMID: 30066367
Sun Y, Argani P, Tickoo SK, Epstein JI
Am J Surg Pathol 2018 Oct;42(10):1396-1401. doi: 10.1097/PAS.0000000000001124. PMID: 30001236
Foshat M, Eyzaguirre E
Arch Pathol Lab Med 2017 Apr;141(4):600-606. doi: 10.5858/arpa.2016-0123-RS. PMID: 28353376
Kuroda N, Ohe C, Mikami S, Hes O, Michal M, Brunelli M, Martignoni G, Sato Y, Yoshino T, Kakehi Y, Shuin T, Lee GH
Histol Histopathol 2011 Sep;26(9):1215-8. doi: 10.14670/HH-26.1215. PMID: 21751153

Clinical prediction guides

Kondo T, Sassa N, Yamada H, Takagi T, Iizuka J, Kobayashi H, Yoshida K, Fukuda H, Ishihara H, Tanabe K, Tsuzuki T
Pathology 2021 Oct;53(6):720-727. Epub 2021 May 2 doi: 10.1016/j.pathol.2021.01.014. PMID: 33947521
Sun Y, Argani P, Tickoo SK, Epstein JI
Am J Surg Pathol 2018 Oct;42(10):1396-1401. doi: 10.1097/PAS.0000000000001124. PMID: 30001236
Zhu B, Rohan SM, Lin X
Diagn Pathol 2015 Mar 14;10:4. doi: 10.1186/s13000-015-0242-z. PMID: 25889632Free PMC Article
Kuroda N, Yamashita M, Kakehi Y, Hes O, Michal M, Lee GH
Med Mol Morphol 2011 Dec;44(4):228-32. Epub 2011 Dec 17 doi: 10.1007/s00795-010-0496-1. PMID: 22179186
Kuroda N, Ohe C, Mikami S, Hes O, Michal M, Brunelli M, Martignoni G, Sato Y, Yoshino T, Kakehi Y, Shuin T, Lee GH
Histol Histopathol 2011 Sep;26(9):1215-8. doi: 10.14670/HH-26.1215. PMID: 21751153

Recent systematic reviews

Duong NX, Le MK, Nguyen TT, Nguyen DD, Vuong HG, Kondo T, Mitsui T
Clin Genitourin Cancer 2024 Jun;22(3):102050. Epub 2024 Feb 14 doi: 10.1016/j.clgc.2024.02.001. PMID: 38502982

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