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Metastatic Thyroid Gland Papillary Carcinoma

MedGen UID:
1650014
•Concept ID:
C4744568
•
Neoplastic Process

Definition

A papillary carcinoma that arises from the thyroid gland and has metastasized to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Thyroid Gland Papillary Carcinoma

Professional guidelines

PubMed

Diagnosis and Management of Tropomyosin Receptor Kinase Fusion-Positive Thyroid Carcinomas: A Review.
Haddad R, Elisei R, Hoff AO, Liu Z, Pitoia F, Pruneri G, Sadow PM, Soares F, Turk A, Williams MD, Wirth LJ, Cabanillas ME
JAMA Oncol 2023 Aug 1;9(8):1132-1141. doi: 10.1001/jamaoncol.2023.1379. PMID: 37289450
American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.
Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT, Givi B
JAMA Otolaryngol Head Neck Surg 2022 Dec 1;148(12):1156-1163. doi: 10.1001/jamaoto.2022.3360. PMID: 36326739Free PMC Article
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM
Thyroid 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110. PMID: 19860577

Recent clinical studies

Etiology

Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis.
Xu S, Huang H, Huang Y, Qian J, Wang X, Xu Z, Liu S, Liu J
JAMA Surg 2023 Jan 1;158(1):73-79. doi: 10.1001/jamasurg.2022.5781. PMID: 36449303Free PMC Article
American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.
Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT, Givi B
JAMA Otolaryngol Head Neck Surg 2022 Dec 1;148(12):1156-1163. doi: 10.1001/jamaoto.2022.3360. PMID: 36326739Free PMC Article
Prevalence of Hashimoto Thyroiditis in Adults With Papillary Thyroid Cancer and Its Association With Cancer Recurrence and Outcomes.
Xu S, Huang H, Qian J, Liu Y, Huang Y, Wang X, Liu S, Xu Z, Liu J
JAMA Netw Open 2021 Jul 1;4(7):e2118526. doi: 10.1001/jamanetworkopen.2021.18526. PMID: 34313737Free PMC Article
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Update on Fundamental Mechanisms of Thyroid Cancer.
Prete A, Borges de Souza P, Censi S, Muzza M, Nucci N, Sponziello M
Front Endocrinol (Lausanne) 2020;11:102. Epub 2020 Mar 13 doi: 10.3389/fendo.2020.00102. PMID: 32231639Free PMC Article

Diagnosis

American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.
Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT, Givi B
JAMA Otolaryngol Head Neck Surg 2022 Dec 1;148(12):1156-1163. doi: 10.1001/jamaoto.2022.3360. PMID: 36326739Free PMC Article
Application of Immunohistochemistry in Papillary Thyroid Carcinoma.
Lam AK, Lee KT
Methods Mol Biol 2022;2534:175-195. doi: 10.1007/978-1-0716-2505-7_13. PMID: 35670976
Update on Fundamental Mechanisms of Thyroid Cancer.
Prete A, Borges de Souza P, Censi S, Muzza M, Nucci N, Sponziello M
Front Endocrinol (Lausanne) 2020;11:102. Epub 2020 Mar 13 doi: 10.3389/fendo.2020.00102. PMID: 32231639Free PMC Article
Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients.
Liu C, Xiao C, Chen J, Li X, Feng Z, Gao Q, Liu Z
BMC Cancer 2019 Jun 25;19(1):622. doi: 10.1186/s12885-019-5835-6. PMID: 31238891Free PMC Article
Papillary thyroid carcinoma of the isthmus: Total thyroidectomy or isthmusectomy?
Vasileiadis I, Boutzios G, Karalaki M, Misiakos E, Karatzas T
Am J Surg 2018 Jul;216(1):135-139. Epub 2017 Sep 19 doi: 10.1016/j.amjsurg.2017.09.008. PMID: 28954712

Therapy

Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis.
Xu S, Huang H, Huang Y, Qian J, Wang X, Xu Z, Liu S, Liu J
JAMA Surg 2023 Jan 1;158(1):73-79. doi: 10.1001/jamasurg.2022.5781. PMID: 36449303Free PMC Article
American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.
Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT, Givi B
JAMA Otolaryngol Head Neck Surg 2022 Dec 1;148(12):1156-1163. doi: 10.1001/jamaoto.2022.3360. PMID: 36326739Free PMC Article
Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma.
Waguespack SG, Drilon A, Lin JJ, Brose MS, McDermott R, Almubarak M, Bauman J, Casanova M, Krishnamurthy A, Kummar S, Leyvraz S, Oh DY, Park K, Sohal D, Sherman E, Norenberg R, Silvertown JD, Brega N, Hong DS, Cabanillas ME
Eur J Endocrinol 2022 Apr 29;186(6):631-643. doi: 10.1530/EJE-21-1259. PMID: 35333737Free PMC Article
Pralsetinib: First Approval.
Markham A
Drugs 2020 Nov;80(17):1865-1870. doi: 10.1007/s40265-020-01427-4. PMID: 33136236
Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer.
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, Haugen BR, Kloos RT, Lee SL, Mandel SJ, Mazzaferri EL, McIver B, Pacini F, Schlumberger M, Sherman SI, Steward DL, Tuttle RM
Thyroid 2009 Nov;19(11):1167-214. doi: 10.1089/thy.2009.0110. PMID: 19860577

Prognosis

Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis.
Xu S, Huang H, Huang Y, Qian J, Wang X, Xu Z, Liu S, Liu J
JAMA Surg 2023 Jan 1;158(1):73-79. doi: 10.1001/jamasurg.2022.5781. PMID: 36449303Free PMC Article
Radioactive Iodine for Papillary Thyroid Carcinoma.
Chan WWL, Kwong DLW
Methods Mol Biol 2022;2534:225-241. doi: 10.1007/978-1-0716-2505-7_16. PMID: 35670979
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Update on Fundamental Mechanisms of Thyroid Cancer.
Prete A, Borges de Souza P, Censi S, Muzza M, Nucci N, Sponziello M
Front Endocrinol (Lausanne) 2020;11:102. Epub 2020 Mar 13 doi: 10.3389/fendo.2020.00102. PMID: 32231639Free PMC Article
Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients.
Liu C, Xiao C, Chen J, Li X, Feng Z, Gao Q, Liu Z
BMC Cancer 2019 Jun 25;19(1):622. doi: 10.1186/s12885-019-5835-6. PMID: 31238891Free PMC Article

Clinical prediction guides

Aggressive Subtypes of Papillary Thyroid Carcinoma Smaller Than 1 cm.
Lee JS, Lee JS, Yun HJ, Kim SM, Chang H, Lee YS, Chang HS, Park CS
J Clin Endocrinol Metab 2023 May 17;108(6):1370-1375. doi: 10.1210/clinem/dgac739. PMID: 36546348Free PMC Article
Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis.
Xu S, Huang H, Huang Y, Qian J, Wang X, Xu Z, Liu S, Liu J
JAMA Surg 2023 Jan 1;158(1):73-79. doi: 10.1001/jamasurg.2022.5781. PMID: 36449303Free PMC Article
American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.
Gordon AJ, Dublin JC, Patel E, Papazian M, Chow MS, Persky MJ, Jacobson AS, Patel KN, Suh I, Morris LGT, Givi B
JAMA Otolaryngol Head Neck Surg 2022 Dec 1;148(12):1156-1163. doi: 10.1001/jamaoto.2022.3360. PMID: 36326739Free PMC Article
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients.
Liu C, Xiao C, Chen J, Li X, Feng Z, Gao Q, Liu Z
BMC Cancer 2019 Jun 25;19(1):622. doi: 10.1186/s12885-019-5835-6. PMID: 31238891Free PMC Article

Recent systematic reviews

Prevalence of Occult Central Lymph Node Metastasis by Tumor Size in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Tang L, Qu RW, Park J, Simental AA, Inman JC
Curr Oncol 2023 Aug 2;30(8):7335-7350. doi: 10.3390/curroncol30080532. PMID: 37623013Free PMC Article
Chronic Myeloid Leukemia following Exposure to Radioactive Iodine (I131): A Systematic Review.
Ali Hailan YM, Al-Dubai HN, Yassin MA
Oncology 2023;101(6):362-368. Epub 2023 May 9 doi: 10.1159/000530463. PMID: 37231874
Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid: A Systematic Review and Meta-analysis.
van Dijk SPJ, Coerts HI, Gunput STG, van Velsen EFS, Medici M, Moelker A, Peeters RP, Verhoef C, van Ginhoven TM
JAMA Otolaryngol Head Neck Surg 2022 Apr 1;148(4):317-325. doi: 10.1001/jamaoto.2021.4381. PMID: 35142816Free PMC Article
Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.
Mao J, Zhang Q, Zhang H, Zheng K, Wang R, Wang G
Front Endocrinol (Lausanne) 2020;11:265. Epub 2020 May 15 doi: 10.3389/fendo.2020.00265. PMID: 32477264Free PMC Article
Sorafenib in metastatic thyroid cancer: a systematic review.
Thomas L, Lai SY, Dong W, Feng L, Dadu R, Regone RM, Cabanillas ME
Oncologist 2014 Mar;19(3):251-8. Epub 2014 Feb 21 doi: 10.1634/theoncologist.2013-0362. PMID: 24563075Free PMC Article

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