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Methotrexate-Associated Lymphoma

MedGen UID:
1654240
•Concept ID:
C4725917
•
Neoplastic Process

Definition

A non-Hodgkin or Hodgkin lymphoma that develops in patients who are immunosuppressed with methotrexate. [from NCI]

Professional guidelines

PubMed

Risk factors for high-dose methotrexate associated toxicities in patients with primary central nervous system lymphoma.
Sun K, Tao H, Ding T, Li Z, Qiu X, Zhong M, Wu Z
J Clin Pharm Ther 2022 Dec;47(12):2196-2204. Epub 2022 Oct 19 doi: 10.1111/jcpt.13791. PMID: 36259502
Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen.
Kroll M, Kaupat-Bleckmann K, Mörickel A, Altenl J, Schewel DM, Stanullal M, Zimmermann M, Schrappe M, Cario G
Haematologica 2020 Apr;105(4):1013-1020. Epub 2019 Aug 1 doi: 10.3324/haematol.2019.224774. PMID: 31371414Free PMC Article
Spontaneous remission of "methotrexate-associated lymphoproliferative disorders" after discontinuation of immunosuppressive treatment for autoimmune disease. Review of the literature.
Rizzi R, Curci P, Delia M, Rinaldi E, Chiefa A, Specchia G, Liso V
Med Oncol 2009;26(1):1-9. Epub 2008 May 7 doi: 10.1007/s12032-008-9069-8. PMID: 18461290

Recent clinical studies

Etiology

Effects of a biologic agent in a patient with rheumatoid arthritis after treatment for methotrexate-associated B-cell lymphoma: a case report.
Kuroda T, Sato H, Nakatsue T, Wada Y, Murakami S, Nakano M, Narita I
BMC Res Notes 2014 Apr 11;7:229. doi: 10.1186/1756-0500-7-229. PMID: 24721419Free PMC Article

Diagnosis

Effects of a biologic agent in a patient with rheumatoid arthritis after treatment for methotrexate-associated B-cell lymphoma: a case report.
Kuroda T, Sato H, Nakatsue T, Wada Y, Murakami S, Nakano M, Narita I
BMC Res Notes 2014 Apr 11;7:229. doi: 10.1186/1756-0500-7-229. PMID: 24721419Free PMC Article
Methotrexate-associated lymphoma in patients with rheumatoid arthritis: report of two cases.
Bachman TR, Sawitzke AD, Perkins SL, Ward JH, Cannon GW
Arthritis Rheum 1996 Feb;39(2):325-9. doi: 10.1002/art.1780390223. PMID: 8849387

Therapy

Effects of a biologic agent in a patient with rheumatoid arthritis after treatment for methotrexate-associated B-cell lymphoma: a case report.
Kuroda T, Sato H, Nakatsue T, Wada Y, Murakami S, Nakano M, Narita I
BMC Res Notes 2014 Apr 11;7:229. doi: 10.1186/1756-0500-7-229. PMID: 24721419Free PMC Article
Methotrexate-associated lymphoma in patients with rheumatoid arthritis: report of two cases.
Bachman TR, Sawitzke AD, Perkins SL, Ward JH, Cannon GW
Arthritis Rheum 1996 Feb;39(2):325-9. doi: 10.1002/art.1780390223. PMID: 8849387

Prognosis

Effects of a biologic agent in a patient with rheumatoid arthritis after treatment for methotrexate-associated B-cell lymphoma: a case report.
Kuroda T, Sato H, Nakatsue T, Wada Y, Murakami S, Nakano M, Narita I
BMC Res Notes 2014 Apr 11;7:229. doi: 10.1186/1756-0500-7-229. PMID: 24721419Free PMC Article

Clinical prediction guides

Effects of a biologic agent in a patient with rheumatoid arthritis after treatment for methotrexate-associated B-cell lymphoma: a case report.
Kuroda T, Sato H, Nakatsue T, Wada Y, Murakami S, Nakano M, Narita I
BMC Res Notes 2014 Apr 11;7:229. doi: 10.1186/1756-0500-7-229. PMID: 24721419Free PMC Article
Methotrexate-associated lymphoma in patients with rheumatoid arthritis: report of two cases.
Bachman TR, Sawitzke AD, Perkins SL, Ward JH, Cannon GW
Arthritis Rheum 1996 Feb;39(2):325-9. doi: 10.1002/art.1780390223. PMID: 8849387

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