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Unresectable Cutaneous Melanoma

MedGen UID:
1662307
Concept ID:
C4724930
Neoplastic Process
Synonyms: Unresectable Melanoma of Skin; Unresectable Skin Melanoma

Definition

A skin melanoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Cutaneous Melanoma

Professional guidelines

PubMed

Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, Aasi SZ, Aung PP, Barker CA, Bolotin D, Bordeaux JS, Cartee TV, Chandra S, Cho NL, Choi JN, Chung KY, Cliby WA, Dorigo O, Eisen DB, Fujisawa Y, Golda N, Halfdanarson TR, Iavazzo C, Jiang SIB, Kanitakis J, Khan A, Kim JYS, Kuzel TM, Lawrence N, Leitao MM Jr, MacLean AB, Maher IA, Mittal BB, Nehal KS, Ozog DM, Pettaway CA, Ross JS, Rossi AM, Servaes S, Solomon MJ, Thomas VD, Tolia M, Voelzke BB, Waldman A, Wong MK, Zhou Y, Arai N, Brackett A, Ibrahim SA, Kang BY, Poon E, Alam M
JAMA Oncol 2022 Apr 1;8(4):618-628. doi: 10.1001/jamaoncol.2021.7148. PMID: 35050310
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Seth R, Messersmith H, Kaur V, Kirkwood JM, Kudchadkar R, McQuade JL, Provenzano A, Swami U, Weber J, Alluri KC, Agarwala S, Ascierto PA, Atkins MB, Davis N, Ernstoff MS, Faries MB, Gold JS, Guild S, Gyorki DE, Khushalani NI, Meyers MO, Robert C, Santinami M, Sehdev A, Sondak VK, Spurrier G, Tsai KK, van Akkooi A, Funchain P
J Clin Oncol 2020 Nov 20;38(33):3947-3970. Epub 2020 Mar 31 doi: 10.1200/JCO.20.00198. PMID: 32228358

Recent clinical studies

Etiology

Whitman ED, Scherrer E, Ou W, Krepler C
Future Oncol 2020 Jul;16(20):1441-1453. Epub 2020 May 15 doi: 10.2217/fon-2020-0314. PMID: 32410465
Yeung C, Petrella TM, Wright FC, Abadir W, Look Hong NJ
Expert Rev Clin Immunol 2017 Apr;13(4):383-388. Epub 2017 Feb 6 doi: 10.1080/1744666X.2017.1286984. PMID: 28121191
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

Diagnosis

Zhuo H, Zhou L
Pharmazie 2016 Oct 1;71(10):555-561. doi: 10.1691/ph.2016.6683. PMID: 29441921

Therapy

Peil J, Bock F, Kiefer F, Schmidt R, Heindl LM, Cursiefen C, Schlereth SL
Int J Mol Sci 2022 Jan 27;23(3) doi: 10.3390/ijms23031478. PMID: 35163401Free PMC Article
Whitman ED, Scherrer E, Ou W, Krepler C
Future Oncol 2020 Jul;16(20):1441-1453. Epub 2020 May 15 doi: 10.2217/fon-2020-0314. PMID: 32410465
Weitman ES, Zager JS
Clin Exp Metastasis 2018 Aug;35(5-6):495-502. Epub 2018 May 8 doi: 10.1007/s10585-018-9890-1. PMID: 29736626
Yeung C, Petrella TM, Wright FC, Abadir W, Look Hong NJ
Expert Rev Clin Immunol 2017 Apr;13(4):383-388. Epub 2017 Feb 6 doi: 10.1080/1744666X.2017.1286984. PMID: 28121191
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

Prognosis

Whitman ED, Scherrer E, Ou W, Krepler C
Future Oncol 2020 Jul;16(20):1441-1453. Epub 2020 May 15 doi: 10.2217/fon-2020-0314. PMID: 32410465
Yeung C, Petrella TM, Wright FC, Abadir W, Look Hong NJ
Expert Rev Clin Immunol 2017 Apr;13(4):383-388. Epub 2017 Feb 6 doi: 10.1080/1744666X.2017.1286984. PMID: 28121191
Zhuo H, Zhou L
Pharmazie 2016 Oct 1;71(10):555-561. doi: 10.1691/ph.2016.6683. PMID: 29441921

Clinical prediction guides

Yeung C, Petrella TM, Wright FC, Abadir W, Look Hong NJ
Expert Rev Clin Immunol 2017 Apr;13(4):383-388. Epub 2017 Feb 6 doi: 10.1080/1744666X.2017.1286984. PMID: 28121191
Agarwala SS, Eggermont AM, O'Day S, Zager JS
Cancer 2014 Mar 15;120(6):781-9. Epub 2013 Dec 2 doi: 10.1002/cncr.28480. PMID: 24301420

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