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Hypothalamic-Chiasmatic Pilomyxoid Astrocytoma

MedGen UID:
1663605
•Concept ID:
C4744523
•
Neoplastic Process

Definition

A pilomyxoid astrocytoma occurring in the hypothalamic-chiasmatic region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypothalamic-Chiasmatic Pilomyxoid Astrocytoma

Professional guidelines

PubMed

Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome.
Sardi I, Bresci C, Schiavello E, Biassoni V, Fratoni V, Cardellicchio S, Genitori L, Aricò M, Massimino M
J Neurooncol 2012 Sep;109(2):375-83. Epub 2012 Jun 21 doi: 10.1007/s11060-012-0903-7. PMID: 22717669

Recent clinical studies

Therapy

Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome.
Singh G, Wei XC, Hader W, Chan JA, Bouffet E, Lafay-Cousin L
J Pediatr Hematol Oncol 2013 Mar;35(2):e53-6. doi: 10.1097/MPH.0b013e3182707e67. PMID: 23042016
Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome.
Sardi I, Bresci C, Schiavello E, Biassoni V, Fratoni V, Cardellicchio S, Genitori L, Aricò M, Massimino M
J Neurooncol 2012 Sep;109(2):375-83. Epub 2012 Jun 21 doi: 10.1007/s11060-012-0903-7. PMID: 22717669

Prognosis

Pediatric cerebellar pilomyxoid-spectrum astrocytomas.
Forbes JA, Mobley BC, O'Lynnger TM, Cooper CM, Ghiassi M, Hanif R, Pearson MM
J Neurosurg Pediatr 2011 Jul;8(1):90-6. doi: 10.3171/2011.4.PEDS1115. PMID: 21721894Free PMC Article
Pilomyxoid astrocytoma of the cervical spinal cord in a child with rapid progression into glioblastoma: case report and literature review.
Paraskevopoulos D, Patsalas I, Karkavelas G, Foroglou N, Magras I, Selviaridis P
Childs Nerv Syst 2011 Feb;27(2):313-21. Epub 2010 May 12 doi: 10.1007/s00381-010-1171-5. PMID: 20461521
Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization.
Jeon YK, Cheon JE, Kim SK, Wang KC, Cho BK, Park SH
Mod Pathol 2008 Nov;21(11):1345-56. Epub 2008 Jul 11 doi: 10.1038/modpathol.2008.88. PMID: 18622384
Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas.
Komotar RJ, Burger PC, Carson BS, Brem H, Olivi A, Goldthwaite PT, Tihan T
Neurosurgery 2004 Jan;54(1):72-9; discussion 79-80. doi: 10.1227/01.neu.0000097266.89676.25. PMID: 14683543
Pediatric astrocytomas with monomorphous pilomyxoid features and a less favorable outcome.
Tihan T, Fisher PG, Kepner JL, Godfraind C, McComb RD, Goldthwaite PT, Burger PC
J Neuropathol Exp Neurol 1999 Oct;58(10):1061-8. doi: 10.1097/00005072-199910000-00004. PMID: 10515229

Clinical prediction guides

Successful treatment with a low-dose cisplatin--etoposide regimen for patients with diencephalic syndrome.
Sardi I, Bresci C, Schiavello E, Biassoni V, Fratoni V, Cardellicchio S, Genitori L, Aricò M, Massimino M
J Neurooncol 2012 Sep;109(2):375-83. Epub 2012 Jun 21 doi: 10.1007/s11060-012-0903-7. PMID: 22717669
Occipital pilomyxoid astrocytoma in a 14-year-old girl--case report.
Buccoliero AM, Gheri CF, Maio V, Moncini D, Castiglione F, Garbini F, Sanzo M, Taddei A, Genitori L, Taddei GL
Clin Neuropathol 2008 Nov-Dec;27(6):373-7. doi: 10.5414/npp27373. PMID: 19130733

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