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Abnormal astrocyte morphology

MedGen UID:
867605
Concept ID:
C4021991
Finding
Synonym: Abnormality of the astrocytes
 
HPO: HP:0100707

Definition

An abnormality of astrocytes. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal astrocyte morphology

Professional guidelines

PubMed

Ojo JO, Reed JM, Crynen G, Vallabhaneni P, Evans J, Shackleton B, Eisenbaum M, Ringland C, Edsell A, Mullan M, Crawford F, Bachmeier C
Mol Brain 2021 Jul 8;14(1):110. doi: 10.1186/s13041-021-00803-9. PMID: 34238312Free PMC Article
Yang C, Gao Y
Front Biosci (Landmark Ed) 2020 Jun 1;25(9):1718-1731. doi: 10.2741/4874. PMID: 32472754
McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA; TBI/CTE group
Acta Neuropathol 2016 Jan;131(1):75-86. Epub 2015 Dec 14 doi: 10.1007/s00401-015-1515-z. PMID: 26667418Free PMC Article

Recent clinical studies

Etiology

Rustenhoven J, Tanumihardja C, Kipnis J
Circ Res 2021 Jun 25;129(1):174-194. Epub 2021 Jun 24 doi: 10.1161/CIRCRESAHA.121.318173. PMID: 34166075
Dietz AG, Goldman SA, Nedergaard M
Lancet Psychiatry 2020 Mar;7(3):272-281. Epub 2019 Nov 6 doi: 10.1016/S2215-0366(19)30302-5. PMID: 31704113Free PMC Article
Forrest SL, Kril JJ, Halliday GM
Acta Neuropathol 2019 Nov;138(5):705-727. Epub 2019 Jun 15 doi: 10.1007/s00401-019-02035-7. PMID: 31203391
An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey AI, Lah J, Seyfried NT, Legido-Quigley C, O'Brien R, Thambisetty M
Alzheimers Dement 2018 Mar;14(3):318-329. Epub 2017 Oct 19 doi: 10.1016/j.jalz.2017.09.011. PMID: 29055815Free PMC Article
McKee AC, Stein TD, Kiernan PT, Alvarez VE
Brain Pathol 2015 May;25(3):350-64. doi: 10.1111/bpa.12248. PMID: 25904048Free PMC Article

Diagnosis

López-Rivera JA, Leu C, Macnee M, Khoury J, Hoffmann L, Coras R, Kobow K, Bhattarai N, Pérez-Palma E, Hamer H, Brandner S, Rössler K, Bien CG, Kalbhenn T, Pieper T, Hartlieb T, Butler E, Genovese G, Becker K, Altmüller J, Niestroj LM, Ferguson L, Busch RM, Nürnberg P, Najm I, Blümcke I, Lal D
Brain 2023 Apr 19;146(4):1342-1356. doi: 10.1093/brain/awac376. PMID: 36226386Free PMC Article
Shan F, Long Y, Qiu W
Front Immunol 2018;9:2802. Epub 2018 Dec 5 doi: 10.3389/fimmu.2018.02802. PMID: 30568655Free PMC Article
Mckee AC, Abdolmohammadi B, Stein TD
Handb Clin Neurol 2018;158:297-307. doi: 10.1016/B978-0-444-63954-7.00028-8. PMID: 30482357
McKee AC, Stein TD, Kiernan PT, Alvarez VE
Brain Pathol 2015 May;25(3):350-64. doi: 10.1111/bpa.12248. PMID: 25904048Free PMC Article
Collins VP
Cancer Surv 1998;32:37-51. PMID: 10489622

Therapy

Jia X, Gao Z, Hu H
Sci China Life Sci 2021 Jun;64(6):911-925. Epub 2020 Oct 14 doi: 10.1007/s11427-020-1815-6. PMID: 33068286
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee DY, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ
Nat Med 2014 Aug;20(8):886-96. Epub 2014 Jun 29 doi: 10.1038/nm.3639. PMID: 24973918Free PMC Article
Brusilow SW, Koehler RC, Traystman RJ, Cooper AJ
Neurotherapeutics 2010 Oct;7(4):452-70. doi: 10.1016/j.nurt.2010.05.015. PMID: 20880508Free PMC Article
Sofroniew MV
Trends Neurosci 2009 Dec;32(12):638-47. Epub 2009 Sep 24 doi: 10.1016/j.tins.2009.08.002. PMID: 19782411Free PMC Article
Córdoba J, Mínguez B
Semin Liver Dis 2008 Feb;28(1):70-80. doi: 10.1055/s-2008-1040322. PMID: 18293278

Prognosis

Huang W, Xia Q, Zheng F, Zhao X, Ge F, Xiao J, Liu Z, Shen Y, Ye K, Wang D, Li Y
J Alzheimers Dis 2023;94(s1):S335-S354. doi: 10.3233/JAD-221064. PMID: 36683511Free PMC Article
Wang H, Liu Y, Zhao J, Guo X, Hu M, Chen Y
Clin Neurol Neurosurg 2021 Sep;208:106844. Epub 2021 Aug 4 doi: 10.1016/j.clineuro.2021.106844. PMID: 34388595
Shan F, Long Y, Qiu W
Front Immunol 2018;9:2802. Epub 2018 Dec 5 doi: 10.3389/fimmu.2018.02802. PMID: 30568655Free PMC Article
Ling H, Neal JW, Revesz T
Neuropathol Appl Neurobiol 2017 Oct;43(6):467-476. doi: 10.1111/nan.12425. PMID: 28664614
Aldape K, Zadeh G, Mansouri S, Reifenberger G, von Deimling A
Acta Neuropathol 2015 Jun;129(6):829-48. Epub 2015 May 6 doi: 10.1007/s00401-015-1432-1. PMID: 25943888

Clinical prediction guides

López-Rivera JA, Leu C, Macnee M, Khoury J, Hoffmann L, Coras R, Kobow K, Bhattarai N, Pérez-Palma E, Hamer H, Brandner S, Rössler K, Bien CG, Kalbhenn T, Pieper T, Hartlieb T, Butler E, Genovese G, Becker K, Altmüller J, Niestroj LM, Ferguson L, Busch RM, Nürnberg P, Najm I, Blümcke I, Lal D
Brain 2023 Apr 19;146(4):1342-1356. doi: 10.1093/brain/awac376. PMID: 36226386Free PMC Article
Huin V, Coarelli G, Guemy C, Boluda S, Debs R, Mochel F, Stojkovic T, Grabli D, Maisonobe T, Gaymard B, Lenglet T, Tard C, Davion JB, Sablonnière B, Monin ML, Ewenczyk C, Viala K, Charles P, Le Ber I, Reilly MM, Houlden H, Cortese A, Seilhean D, Brice A, Durr A
Brain 2022 Jun 30;145(6):2121-2132. doi: 10.1093/brain/awab449. PMID: 34927205
Shan F, Long Y, Qiu W
Front Immunol 2018;9:2802. Epub 2018 Dec 5 doi: 10.3389/fimmu.2018.02802. PMID: 30568655Free PMC Article
Aldape K, Zadeh G, Mansouri S, Reifenberger G, von Deimling A
Acta Neuropathol 2015 Jun;129(6):829-48. Epub 2015 May 6 doi: 10.1007/s00401-015-1432-1. PMID: 25943888
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee DY, Hong J, Kim HY, Oh SJ, Park SJ, Lee H, Yoon BE, Kim Y, Jeong Y, Shim I, Bae YC, Cho J, Kowall NW, Ryu H, Hwang E, Kim D, Lee CJ
Nat Med 2014 Aug;20(8):886-96. Epub 2014 Jun 29 doi: 10.1038/nm.3639. PMID: 24973918Free PMC Article

Recent systematic reviews

Ryken TC, Parney I, Buatti J, Kalkanis SN, Olson JJ
J Neurooncol 2015 Dec;125(3):551-83. Epub 2015 Nov 3 doi: 10.1007/s11060-015-1948-1. PMID: 26530266
Gouw AA, Seewann A, van der Flier WM, Barkhof F, Rozemuller AM, Scheltens P, Geurts JJ
J Neurol Neurosurg Psychiatry 2011 Feb;82(2):126-35. Epub 2010 Oct 9 doi: 10.1136/jnnp.2009.204685. PMID: 20935330
Gripp KW, Hopkins E, Doyle D, Dobyns WB
Am J Med Genet A 2010 May;152A(5):1161-8. doi: 10.1002/ajmg.a.33391. PMID: 20425820Free PMC Article

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