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Unresectable Intrahepatic Cholangiocarcinoma

MedGen UID:
1664280
Concept ID:
C4725028
Neoplastic Process

Definition

Intrahepatic cholangiocarcinoma that is not amenable to surgical removal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Intrahepatic Cholangiocarcinoma

Professional guidelines

PubMed

Kis B, Shridhar R, Mhaskar R, Gyano M, Frakes JM, El-Haddad G, Choi J, Kim RD, Hoffe SE
J Vasc Interv Radiol 2023 Sep;34(9):1547-1555. Epub 2023 May 18 doi: 10.1016/j.jvir.2023.05.026. PMID: 37210030
Liu D, Wang J, Ma Z, Zhang N, Zhao Y, Yang X, Wen Z, Xie H
Cardiovasc Intervent Radiol 2022 Aug;45(8):1092-1101. Epub 2022 May 19 doi: 10.1007/s00270-022-03108-z. PMID: 35588011
Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS
Eur J Surg Oncol 2015 Jan;41(1):120-7. Epub 2014 Oct 7 doi: 10.1016/j.ejso.2014.09.007. PMID: 25449754Free PMC Article

Recent clinical studies

Etiology

Franssen S, Holster JJ, Jolissaint JS, Nooijen LE, Cercek A, D'Angelica MI, Homs MYV, Wei AC, Balachandran VP, Drebin JA, Harding JJ, Kemeny NE, Kingham TP, Klümpen HJ, Mostert B, Swijnenburg RJ, Soares KC, Jarnagin WR, Groot Koerkamp B
Ann Surg Oncol 2024 Jan;31(1):115-124. Epub 2023 Oct 9 doi: 10.1245/s10434-023-14409-z. PMID: 37814188Free PMC Article
Gupta AN, Gordon AC, Gabr A, Kalyan A, Kircher SM, Mahalingam D, Mulcahy MF, Merkow RP, Yang AD, Bentrem DJ, Caicedo-Ramirez JC, Riaz A, Thornburg B, Desai K, Sato KT, Hohlastos ES, Kulik L, Benson AB, Salem R, Lewandowski RJ
Cardiovasc Intervent Radiol 2022 Aug;45(8):1117-1128. Epub 2022 Jun 22 doi: 10.1007/s00270-022-03183-2. PMID: 35732931
Liu D, Wang J, Ma Z, Zhang N, Zhao Y, Yang X, Wen Z, Xie H
Cardiovasc Intervent Radiol 2022 Aug;45(8):1092-1101. Epub 2022 May 19 doi: 10.1007/s00270-022-03108-z. PMID: 35588011
Holster JJ, El Hassnaoui M, Franssen S, IJzermans JNM, de Jonge J, Mostert B, Polak WG, de Wilde RF, Homs MYV, Groot Koerkamp B
Ann Surg Oncol 2022 Sep;29(9):5528-5538. Epub 2022 Mar 16 doi: 10.1245/s10434-022-11439-x. PMID: 35294656Free PMC Article
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272

Diagnosis

Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Hu EY, Bhagavatula S, Shi A, Tuncali K, Levesque V, Shyn PB
J Vasc Interv Radiol 2023 Jun;34(6):1007-1014. Epub 2023 Feb 25 doi: 10.1016/j.jvir.2023.02.024. PMID: 36842534
Panettieri E, Maki H, Kim BJ, Kang HC, Cox V, Vega EA, Mizuno T, Pant S, Javle M, Vauthey JN, Kawaguchi Y
Surg Oncol 2022 Mar;40:101696. Epub 2021 Dec 31 doi: 10.1016/j.suronc.2021.101696. PMID: 34995974Free PMC Article
Smart AC, Goyal L, Horick N, Petkovska N, Zhu AX, Ferrone CR, Tanabe KK, Allen JN, Drapek LC, Qadan M, Murphy JE, Eyler CE, Ryan DP, Hong TS, Wo JY
Ann Surg Oncol 2020 Apr;27(4):1122-1129. Epub 2019 Dec 23 doi: 10.1245/s10434-019-08142-9. PMID: 31873931
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article

Therapy

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Schartz DA, Porter M, Schartz E, Kallas J, Gupta A, Butani D, Cantos A
J Vasc Interv Radiol 2022 Jun;33(6):679-686. Epub 2022 Feb 25 doi: 10.1016/j.jvir.2022.02.016. PMID: 35219834
McMillan RR, Javle M, Kodali S, Saharia A, Mobley C, Heyne K, Hobeika MJ, Lunsford KE, Victor DW 3rd, Shetty A, McFadden RS, Abdelrahim M, Kaseb A, Divatia M, Yu N, Nolte Fong J, Moore LW, Nguyen DT, Graviss EA, Gaber AO, Vauthey JN, Ghobrial RM
Am J Transplant 2022 Mar;22(3):823-832. Epub 2021 Dec 27 doi: 10.1111/ajt.16906. PMID: 34856069
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article
Edeline J, Touchefeu Y, Guiu B, Farge O, Tougeron D, Baumgaertner I, Ayav A, Campillo-Gimenez B, Beuzit L, Pracht M, Lièvre A, Le Sourd S, Boudjema K, Rolland Y, Boucher E, Garin E
JAMA Oncol 2020 Jan 1;6(1):51-59. doi: 10.1001/jamaoncol.2019.3702. PMID: 31670746Free PMC Article

Prognosis

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
McMillan RR, Javle M, Kodali S, Saharia A, Mobley C, Heyne K, Hobeika MJ, Lunsford KE, Victor DW 3rd, Shetty A, McFadden RS, Abdelrahim M, Kaseb A, Divatia M, Yu N, Nolte Fong J, Moore LW, Nguyen DT, Graviss EA, Gaber AO, Vauthey JN, Ghobrial RM
Am J Transplant 2022 Mar;22(3):823-832. Epub 2021 Dec 27 doi: 10.1111/ajt.16906. PMID: 34856069
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article
Edeline J, Touchefeu Y, Guiu B, Farge O, Tougeron D, Baumgaertner I, Ayav A, Campillo-Gimenez B, Beuzit L, Pracht M, Lièvre A, Le Sourd S, Boudjema K, Rolland Y, Boucher E, Garin E
JAMA Oncol 2020 Jan 1;6(1):51-59. doi: 10.1001/jamaoncol.2019.3702. PMID: 31670746Free PMC Article

Clinical prediction guides

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Zhang XX, Ma HB, Li TH, Huang B, Jia NY, Meng Y
Clin Transl Oncol 2023 Mar;25(3):731-738. Epub 2022 Nov 19 doi: 10.1007/s12094-022-02979-5. PMID: 36401766
Liu D, Wang J, Ma Z, Zhang N, Zhao Y, Yang X, Wen Z, Xie H
Cardiovasc Intervent Radiol 2022 Aug;45(8):1092-1101. Epub 2022 May 19 doi: 10.1007/s00270-022-03108-z. PMID: 35588011
McMillan RR, Javle M, Kodali S, Saharia A, Mobley C, Heyne K, Hobeika MJ, Lunsford KE, Victor DW 3rd, Shetty A, McFadden RS, Abdelrahim M, Kaseb A, Divatia M, Yu N, Nolte Fong J, Moore LW, Nguyen DT, Graviss EA, Gaber AO, Vauthey JN, Ghobrial RM
Am J Transplant 2022 Mar;22(3):823-832. Epub 2021 Dec 27 doi: 10.1111/ajt.16906. PMID: 34856069

Recent systematic reviews

Holster JJ, El Hassnaoui M, Franssen S, IJzermans JNM, de Jonge J, Mostert B, Polak WG, de Wilde RF, Homs MYV, Groot Koerkamp B
Ann Surg Oncol 2022 Sep;29(9):5528-5538. Epub 2022 Mar 16 doi: 10.1245/s10434-022-11439-x. PMID: 35294656Free PMC Article
Schartz DA, Porter M, Schartz E, Kallas J, Gupta A, Butani D, Cantos A
J Vasc Interv Radiol 2022 Jun;33(6):679-686. Epub 2022 Feb 25 doi: 10.1016/j.jvir.2022.02.016. PMID: 35219834
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272
Han K, Ko HK, Kim KW, Won HJ, Shin YM, Kim PN
J Vasc Interv Radiol 2015 Jul;26(7):943-8. Epub 2015 Apr 18 doi: 10.1016/j.jvir.2015.02.024. PMID: 25899049
Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS
Eur J Surg Oncol 2015 Jan;41(1):120-7. Epub 2014 Oct 7 doi: 10.1016/j.ejso.2014.09.007. PMID: 25449754Free PMC Article

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