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Distal Esophagus Squamous Cell Carcinoma

MedGen UID:
1668587
•Concept ID:
C4725599
•
Neoplastic Process
Synonyms: Squamous Cell Carcinoma of the Distal Esophagus; Squamous Cell Carcinoma of the Lower Third of the Esophagus

Definition

A squamous cell carcinoma that arises from the distal esophagus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDistal Esophagus Squamous Cell Carcinoma

Professional guidelines

PubMed

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Esophageal cancer: diagnosis and management.
Lin SH, Chang JY
Chin J Cancer 2010 Oct;29(10):843-54. doi: 10.5732/cjc.010.10151. PMID: 20868553
Treatment of malignant esophageal obstruction with silicone-coated metallic self-expanding stents.
Schaer J, Katon RM, Ivancev K, Uchida B, Rösch J, Binmoeller K
Gastrointest Endosc 1992 Jan-Feb;38(1):7-11. doi: 10.1016/s0016-5107(92)70322-8. PMID: 1377148

Recent clinical studies

Etiology

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Impact of the 7th Edition AJCC staging classification on the NCCN clinical practice guidelines in oncology for gastric and esophageal cancers.
Strong VE, D'Amico TA, Kleinberg L, Ajani J
J Natl Compr Canc Netw 2013 Jan 1;11(1):60-6. doi: 10.6004/jnccn.2013.0009. PMID: 23307982
Esophageal cancer: diagnosis and management.
Lin SH, Chang JY
Chin J Cancer 2010 Oct;29(10):843-54. doi: 10.5732/cjc.010.10151. PMID: 20868553
Barrett's oesophagus: an ideal model to study cancer genetics.
di Pietro M, Fitzgerald RC
Hum Genet 2009 Aug;126(2):233-46. Epub 2009 Apr 14 doi: 10.1007/s00439-009-0665-2. PMID: 19365640
Improved prognosis of resected esophageal cancer.
Stein HJ, Siewert JR
World J Surg 2004 Jun;28(6):520-5. doi: 10.1007/s00268-004-7417-1. PMID: 15366737

Diagnosis

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Esophageal cancer: diagnosis and management.
Lin SH, Chang JY
Chin J Cancer 2010 Oct;29(10):843-54. doi: 10.5732/cjc.010.10151. PMID: 20868553
Barrett's oesophagus: an ideal model to study cancer genetics.
di Pietro M, Fitzgerald RC
Hum Genet 2009 Aug;126(2):233-46. Epub 2009 Apr 14 doi: 10.1007/s00439-009-0665-2. PMID: 19365640
Adenocarcinoma in a mid-esophageal diverticulum.
Avisar E, Luketich JD
Ann Thorac Surg 2000 Jan;69(1):288-9. doi: 10.1016/s0003-4975(99)01201-1. PMID: 10654542
Primary esophageal lymphoepithelioma.
Parra P, Aguilar J, López-Garrido J, Meléndez B, Merino E, Martinez, Gordillo E, Roldán JP
Tumori 1999 Nov-Dec;85(6):519-22. doi: 10.1177/030089169908500619. PMID: 10774578

Therapy

Diagnosis and management of Barrett esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
Weusten BLAM, Bisschops R, Dinis-Ribeiro M, di Pietro M, Pech O, Spaander MCW, Baldaque-Silva F, Barret M, Coron E, Fernández-Esparrach G, Fitzgerald RC, Jansen M, Jovani M, Marques-de-Sa I, Rattan A, Tan WK, Verheij EPD, Zellenrath PA, Triantafyllou K, Pouw RE
Endoscopy 2023 Dec;55(12):1124-1146. Epub 2023 Oct 9 doi: 10.1055/a-2176-2440. PMID: 37813356
Surgery for esophageal cancer: goals of resection and optimizing outcomes.
Rizk N
Thorac Surg Clin 2013 Nov;23(4):491-8. Epub 2013 Oct 13 doi: 10.1016/j.thorsurg.2013.07.009. PMID: 24199699
New insights in the lymphatic spread of oesophageal cancer and its implications for the extent of surgical resection.
Cense HA, van Eijck CH, Tilanus HW
Best Pract Res Clin Gastroenterol 2006;20(5):893-906. doi: 10.1016/j.bpg.2006.03.010. PMID: 16997168
Multimodality therapy for resectable cancer of the thoracic esophagus.
Entwistle JW 3rd, Goldberg M
Ann Thorac Surg 2002 Mar;73(3):1009-15. doi: 10.1016/s0003-4975(01)03148-4. PMID: 11899954
Proximal strictures of the esophagus.
Kozarek RA
J Clin Gastroenterol 1984 Dec;6(6):505-11. doi: 10.1097/00004836-198412000-00004. PMID: 6512226

Prognosis

Impact of the 7th Edition AJCC staging classification on the NCCN clinical practice guidelines in oncology for gastric and esophageal cancers.
Strong VE, D'Amico TA, Kleinberg L, Ajani J
J Natl Compr Canc Netw 2013 Jan 1;11(1):60-6. doi: 10.6004/jnccn.2013.0009. PMID: 23307982
Barrett's oesophagus: an ideal model to study cancer genetics.
di Pietro M, Fitzgerald RC
Hum Genet 2009 Aug;126(2):233-46. Epub 2009 Apr 14 doi: 10.1007/s00439-009-0665-2. PMID: 19365640
Improved prognosis of resected esophageal cancer.
Stein HJ, Siewert JR
World J Surg 2004 Jun;28(6):520-5. doi: 10.1007/s00268-004-7417-1. PMID: 15366737
Adenocarcinoma in a mid-esophageal diverticulum.
Avisar E, Luketich JD
Ann Thorac Surg 2000 Jan;69(1):288-9. doi: 10.1016/s0003-4975(99)01201-1. PMID: 10654542
Pharyngolaryngectomy with extrathoracic esophagectomy.
Davidge-Pitts KJ, Mannel A
Head Neck Surg 1983 Sep-Oct;6(1):571-4. doi: 10.1002/hed.2890060105. PMID: 6629793

Clinical prediction guides

TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines.
Jiang YY, Jiang Y, Li CQ, Zhang Y, Dakle P, Kaur H, Deng JW, Lin RY, Han L, Xie JJ, Yan Y, Doan N, Zheng Y, Mayakonda A, Hazawa M, Xu L, Li Y, Aswad L, Jeitany M, Kanojia D, Guan XY, Said JW, Yang W, Fullwood MJ, Lin DC, Koeffler HP
Gastroenterology 2020 Oct;159(4):1311-1327.e19. Epub 2020 Jun 30 doi: 10.1053/j.gastro.2020.06.050. PMID: 32619460
Indocyanine green fluorescence and three-dimensional imaging of right gastroepiploic artery in gastric tube cancer.
Nakano T, Sakurai T, Maruyama S, Ozawa Y, Kamei T, Miyata G, Ohuchi N
World J Gastroenterol 2015 Jan 7;21(1):369-72. doi: 10.3748/wjg.v21.i1.369. PMID: 25574113Free PMC Article
Esophageal reconstruction with remnant stomach: a case report and review of literature.
Xie SP, Fan GH, Kang GJ, Geng Q, Huang J, Cheng BC
World J Gastroenterol 2013 May 28;19(20):3169-72. doi: 10.3748/wjg.v19.i20.3169. PMID: 23717001Free PMC Article
Improved prognosis of resected esophageal cancer.
Stein HJ, Siewert JR
World J Surg 2004 Jun;28(6):520-5. doi: 10.1007/s00268-004-7417-1. PMID: 15366737
Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.
Meyers WC, Seigler HF, Hanks JB, Thompson WM, Postlethwait R, Jones RS, Akwari OK, Cole TB
Ann Surg 1980;192(4):439-50. doi: 10.1097/00000658-198010000-00002. PMID: 6158920Free PMC Article

Recent systematic reviews

Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer.
Vellayappan BA, Soon YY, Ku GY, Leong CN, Lu JJ, Tey JC
Cochrane Database Syst Rev 2017 Aug 22;8(8):CD010511. doi: 10.1002/14651858.CD010511.pub2. PMID: 28829911Free PMC Article
Longitudinal and circumferential resection margin in adenocarcinoma of distal esophagus and cardia.
Migliore M, Rassl D, Criscione A
Future Oncol 2014 Apr;10(5):891-901. doi: 10.2217/fon.13.241. PMID: 24799068

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