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Decreased circulating hydroxyproline concentration

MedGen UID:
1670945
•Concept ID:
C4732895
•
Finding
Synonyms: Decreased hydroxyproline in the blood; Low level of hydroxyproline in the blood
 
HPO: HP:0500140

Definition

A decreased amount of hydroxyproline in the blood. [from HPO]

Professional guidelines

PubMed

Clodronate in the medical management of hyperparathyroidism.
Hamdy NA, Gray RE, McCloskey E, Galloway J, Rattenbury JM, Brown CB, Kanis JA
Bone 1987;8 Suppl 1:S69-77. PMID: 2961358

Recent clinical studies

Etiology

Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease.
Brilla CG, Funck RC, Rupp H
Circulation 2000 Sep 19;102(12):1388-93. doi: 10.1161/01.cir.102.12.1388. PMID: 10993857
Short-term intravenous bisphosphonates in prevention of postmenopausal bone loss.
Heikkinen JE, Selander KS, Laitinen K, Arnala I, Väänänen HK
J Bone Miner Res 1997 Jan;12(1):103-10. doi: 10.1359/jbmr.1997.12.1.103. PMID: 9240732
Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women.
Holloway L, Butterfield G, Hintz RL, Gesundheit N, Marcus R
J Clin Endocrinol Metab 1994 Aug;79(2):470-9. doi: 10.1210/jcem.79.2.7519191. PMID: 7519191
Transdermal estradiol in the treatment of postmenopausal bone loss.
Adami S, Suppi R, Bertoldo F, Rossini M, Residori M, Maresca V, Lo Cascio V
Bone Miner 1989 Aug;7(1):79-86. doi: 10.1016/0169-6009(89)90064-0. PMID: 2670019
The role of serum concentrations of sex steroids and bone turnover in the development and occurrence of postmenopausal osteoporosis.
Riis BJ, Rødbro P, Christiansen C
Calcif Tissue Int 1986 Jun;38(6):318-22. doi: 10.1007/BF02555743. PMID: 3089552

Diagnosis

Sensitive detection of abnormal aortic architecture in Marfan syndrome with high-frequency ultrasonic tissue characterization.
Recchia D, Sharkey AM, Bosner MS, Kouchoukos NT, Wickline SA
Circulation 1995 Feb 15;91(4):1036-43. doi: 10.1161/01.cir.91.4.1036. PMID: 7850939
Effects of short term administration of recombinant human growth hormone to elderly people.
Marcus R, Butterfield G, Holloway L, Gilliland L, Baylink DJ, Hintz RL, Sherman BM
J Clin Endocrinol Metab 1990 Feb;70(2):519-27. doi: 10.1210/jcem-70-2-519. PMID: 2298863

Therapy

Disruption of GCN2 Pathway Aggravates Vascular and Parenchymal Remodeling during Pulmonary Fibrosis.
Santos-Ribeiro D, Lecocq M, de Beukelaer M, Verleden S, Bouzin C, Ambroise J, Dorfmuller P, Yakoub Y, Huaux F, Quarck R, Karmouty-Quintana H, Ghigna MR, Bignard J, Nadaud S, Soubrier F, Horman S, Perros F, Godinas L, Pilette C
Am J Respir Cell Mol Biol 2023 Mar;68(3):326-338. doi: 10.1165/rcmb.2021-0541OC. PMID: 36476191
Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease.
Brilla CG, Funck RC, Rupp H
Circulation 2000 Sep 19;102(12):1388-93. doi: 10.1161/01.cir.102.12.1388. PMID: 10993857
Effects of short term administration of recombinant human growth hormone to elderly people.
Marcus R, Butterfield G, Holloway L, Gilliland L, Baylink DJ, Hintz RL, Sherman BM
J Clin Endocrinol Metab 1990 Feb;70(2):519-27. doi: 10.1210/jcem-70-2-519. PMID: 2298863
Transdermal estradiol in the treatment of postmenopausal bone loss.
Adami S, Suppi R, Bertoldo F, Rossini M, Residori M, Maresca V, Lo Cascio V
Bone Miner 1989 Aug;7(1):79-86. doi: 10.1016/0169-6009(89)90064-0. PMID: 2670019
Biologic effects of transdermal estradiol.
Chetkowski RJ, Meldrum DR, Steingold KA, Randle D, Lu JK, Eggena P, Hershman JM, Alkjaersig NK, Fletcher AP, Judd HL
N Engl J Med 1986 Jun 19;314(25):1615-20. doi: 10.1056/NEJM198606193142505. PMID: 3012339

Prognosis

Short-term intravenous bisphosphonates in prevention of postmenopausal bone loss.
Heikkinen JE, Selander KS, Laitinen K, Arnala I, Väänänen HK
J Bone Miner Res 1997 Jan;12(1):103-10. doi: 10.1359/jbmr.1997.12.1.103. PMID: 9240732
Transdermal estradiol in the treatment of postmenopausal bone loss.
Adami S, Suppi R, Bertoldo F, Rossini M, Residori M, Maresca V, Lo Cascio V
Bone Miner 1989 Aug;7(1):79-86. doi: 10.1016/0169-6009(89)90064-0. PMID: 2670019

Clinical prediction guides

Sensitive detection of abnormal aortic architecture in Marfan syndrome with high-frequency ultrasonic tissue characterization.
Recchia D, Sharkey AM, Bosner MS, Kouchoukos NT, Wickline SA
Circulation 1995 Feb 15;91(4):1036-43. doi: 10.1161/01.cir.91.4.1036. PMID: 7850939
Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women.
Holloway L, Butterfield G, Hintz RL, Gesundheit N, Marcus R
J Clin Endocrinol Metab 1994 Aug;79(2):470-9. doi: 10.1210/jcem.79.2.7519191. PMID: 7519191
Effects of short term administration of recombinant human growth hormone to elderly people.
Marcus R, Butterfield G, Holloway L, Gilliland L, Baylink DJ, Hintz RL, Sherman BM
J Clin Endocrinol Metab 1990 Feb;70(2):519-27. doi: 10.1210/jcem-70-2-519. PMID: 2298863
Effects of estrogen on daylong circulating calcium, phosphorus, 1,25-dihydroxyvitamin D, and parathyroid hormone in postmenopausal women.
Packer E, Holloway L, Newhall K, Kanwar G, Butterfield G, Marcus R
J Bone Miner Res 1990 Aug;5(8):877-84. doi: 10.1002/jbmr.5650050812. PMID: 2173358

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