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Abnormal circulating tyrosine concentration

MedGen UID:
1684690
•Concept ID:
C5139049
•
Finding
Synonym: Abnormality of tyrosine metabolism
 
HPO: HP:0010917

Definition

Any deviation from the normal concentration of tyrosine in the blood circulation. [from HPO]

Professional guidelines

PubMed

Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article

Recent clinical studies

Etiology

Vascular endothelial growth factors and risk of cardio-renal events: Results from the CREDENCE trial.
Januzzi JL Jr, Liu Y, Sattar N, Yavin Y, Pollock CA, Butler J, Jardine M, Heerspink HJL, Masson S, Breyer M, Hansen MK
Am Heart J 2024 May;271:38-47. Epub 2024 Feb 22 doi: 10.1016/j.ahj.2024.02.016. PMID: 38401646
Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516

Diagnosis

Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516
PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity.
Kumakura Y, Vernaleken I, Gründer G, Bartenstein P, Gjedde A, Cumming P
J Cereb Blood Flow Metab 2005 Jul;25(7):807-19. doi: 10.1038/sj.jcbfm.9600079. PMID: 15729292
DOPA metabolism in neuroblastoma.
Helson L, Johnson GA, Smith R
Med Pediatr Oncol 1980;8(4):317-22. doi: 10.1002/mpo.2950080402. PMID: 6779102

Therapy

Vascular endothelial growth factors and risk of cardio-renal events: Results from the CREDENCE trial.
Januzzi JL Jr, Liu Y, Sattar N, Yavin Y, Pollock CA, Butler J, Jardine M, Heerspink HJL, Masson S, Breyer M, Hansen MK
Am Heart J 2024 May;271:38-47. Epub 2024 Feb 22 doi: 10.1016/j.ahj.2024.02.016. PMID: 38401646
Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article
A decrease in D-dimer concentration and an occurrence of skin rash as iatrogenic events and complementary predictors of survival in lung cancer patients treated with EGFR tyrosine kinase inhibitors.
Zaborowska-Szmit M, Kowalski DM, Piórek A, Krzakowski M, Szmit S
Pharmacol Rep 2016 Dec;68(6):1140-1148. Epub 2016 Jul 20 doi: 10.1016/j.pharep.2016.07.003. PMID: 27588390
Disorders of prolactin and growth hormone secretion.
Ho KY, Evans WS, Thorner MO
Clin Endocrinol Metab 1985 Feb;14(1):1-32. doi: 10.1016/s0300-595x(85)80063-3. PMID: 3926353
Prolactin secretion in Parkinson disease.
Eisler T, Thorner MO, MacLeod RM, Kaiser DL, Calne DB
Neurology 1981 Oct;31(10):1356-9. doi: 10.1212/wnl.31.10.1356. PMID: 6810204

Prognosis

Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM
Int J Mol Sci 2019 Mar 14;20(6) doi: 10.3390/ijms20061280. PMID: 30875730Free PMC Article
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516
DOPA metabolism in neuroblastoma.
Helson L, Johnson GA, Smith R
Med Pediatr Oncol 1980;8(4):317-22. doi: 10.1002/mpo.2950080402. PMID: 6779102

Clinical prediction guides

Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Chaiworapongsa T, Romero R, Gomez-Lopez N, Suksai M, Gallo DM, Jung E, Berry SM, Awonuga A, Tarca AL, Bryant DR
Am J Obstet Gynecol 2024 Apr;230(4):450.e1-450.e18. Epub 2023 Oct 6 doi: 10.1016/j.ajog.2023.10.002. PMID: 37806612Free PMC Article
Angiogenic Biomarkers for Risk Stratification in Women with Preeclampsia.
Docheva N, Arenas G, Nieman KM, Lopes-Perdigao J, Yeo KJ, Rana S
Clin Chem 2022 Jun 1;68(6):771-781. doi: 10.1093/clinchem/hvab281. PMID: 35092286
Angiogenic factors and preeclampsia.
Tjoa ML, Levine RJ, Karumanchi SA
Front Biosci 2007 Jan 1;12:2395-402. doi: 10.2741/2241. PMID: 17127249
Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Lam C, Lim KH, Karumanchi SA
Hypertension 2005 Nov;46(5):1077-85. Epub 2005 Oct 17 doi: 10.1161/01.HYP.0000187899.34379.b0. PMID: 16230516
DOPA metabolism in neuroblastoma.
Helson L, Johnson GA, Smith R
Med Pediatr Oncol 1980;8(4):317-22. doi: 10.1002/mpo.2950080402. PMID: 6779102

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