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Abnormal CSF histidine concentration

MedGen UID:: 1687425
•Concept ID:: C5139620
•: Finding

Synonym:	Abnormal histidine levels in cerebrospinal fluid

HPO:	HP:0500235

Definition

Any deviation from the normal concentration of histidine in the cerebrospinal fluid. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal CSF histidine concentration

Abnormal nervous system morphology
- Morphological central nervous system abnormality
  - Abnormal cerebrospinal fluid morphology
    - Abnormal CSF metabolite concentration
      - Abnormal CSF carboxylic acid concentration
        Abnormal CSF amino acid concentration
        Abnormal CSF histidine concentration
        Decreased CSF histidine concentration
        Increased CSF histidine concentration

Recent clinical studies

Etiology

Changes in free amino acids of cerebrospinal fluid and plasma in various neurological diseases.

Iijima K, Takase S, Tsumuraya K, Endo M, Itahara K
Tohoku J Exp Med 1978 Oct;126(2):133-50. doi: 10.1620/tjem.126.133. PMID: 715764

Clinical prediction guides

High resolution proton nuclear magnetic resonance studies of human cerebrospinal fluid.

Bell JD, Brown JC, Sadler PJ, Macleod AF, Sönksen PH, Hughes RD, Williams R
Clin Sci (Lond) 1987 May;72(5):563-70. doi: 10.1042/cs0720563. PMID: 3034477

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