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Decreased circulating IgG subclass concentration

MedGen UID:
1691048
•Concept ID:
C5139655
•
Finding
Synonyms: Decreased circulating IgG subclass level; Decreased IgG subclass level in blood
 
HPO: HP:0032135

Definition

A reduction below the normal concentration of a subclass of immunoglobulin G (IgG) in the blood. [from HPO]

Recent clinical studies

Etiology

New insight of human-IgH 3'regulatory regions in immunoglobulins switch.
Cianci R, Mancino G, Galli E, Serone E, Massoud R, D'Addabbo P, Poscia A, Borghetti A, Porzio O, Marmo R, Gambassi G, Frezza D
Gene 2023 Apr 30;862:147254. Epub 2023 Feb 9 doi: 10.1016/j.gene.2023.147254. PMID: 36764340
Evidence for differential effects of sulphasalazine on systemic and mucosal immunity in rheumatoid arthritis.
Kanerud L, Engström GN, Tarkowski A
Ann Rheum Dis 1995 Apr;54(4):256-62. doi: 10.1136/ard.54.4.256. PMID: 7763101Free PMC Article

Diagnosis

Quantitative analysis of immunoglobulin subclasses and subclass specific glycosylation by LC-MS-MRM in liver disease.
Yuan W, Sanda M, Wu J, Koomen J, Goldman R
J Proteomics 2015 Feb 26;116:24-33. Epub 2015 Jan 9 doi: 10.1016/j.jprot.2014.12.020. PMID: 25582524Free PMC Article

Therapy

Quantitative analysis of immunoglobulin subclasses and subclass specific glycosylation by LC-MS-MRM in liver disease.
Yuan W, Sanda M, Wu J, Koomen J, Goldman R
J Proteomics 2015 Feb 26;116:24-33. Epub 2015 Jan 9 doi: 10.1016/j.jprot.2014.12.020. PMID: 25582524Free PMC Article
Immunoadsorbent apheresis eliminates pathogenic IgG in childhood lupus nephritis.
Takahashi S, Wada N, Harada K
Pediatr Int 2007 Dec;49(6):817-21. doi: 10.1111/j.1442-200X.2007.02452.x. PMID: 18045278
Recombinant interleukin-2 infusions and decreased IgG2 subclass concentrations.
Soiffer RJ, Murray C, Ritz J, Phillips N, Jacobsohn D, Chartier S, Ambrosino DM
Blood 1995 Feb 15;85(4):925-8. PMID: 7849314
Evidence for differential effects of sulphasalazine on systemic and mucosal immunity in rheumatoid arthritis.
Kanerud L, Engström GN, Tarkowski A
Ann Rheum Dis 1995 Apr;54(4):256-62. doi: 10.1136/ard.54.4.256. PMID: 7763101Free PMC Article

Clinical prediction guides

Quantitative analysis of immunoglobulin subclasses and subclass specific glycosylation by LC-MS-MRM in liver disease.
Yuan W, Sanda M, Wu J, Koomen J, Goldman R
J Proteomics 2015 Feb 26;116:24-33. Epub 2015 Jan 9 doi: 10.1016/j.jprot.2014.12.020. PMID: 25582524Free PMC Article
Evolution of maternofetal transport of immunoglobulins during human pregnancy.
Malek A, Sager R, Kuhn P, Nicolaides KH, Schneider H
Am J Reprod Immunol 1996 Nov;36(5):248-55. doi: 10.1111/j.1600-0897.1996.tb00172.x. PMID: 8955500
Evidence for differential effects of sulphasalazine on systemic and mucosal immunity in rheumatoid arthritis.
Kanerud L, Engström GN, Tarkowski A
Ann Rheum Dis 1995 Apr;54(4):256-62. doi: 10.1136/ard.54.4.256. PMID: 7763101Free PMC Article
Isotypes and IgG subclasses of anti-Fab antibodies in human immunodeficiency virus-infected hemophilia patients.
Süsal C, Oberg HH, Daniel V, Dörr C, Terness P, Huth-Kühne A, Zimmermann R, Opelz G
Vox Sang 1994;66(1):37-45. doi: 10.1111/j.1423-0410.1994.tb00274.x. PMID: 7908473
Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin.
Nonoyama S, Farrington M, Ishida H, Howard M, Ochs HD
J Clin Invest 1993 Sep;92(3):1282-7. doi: 10.1172/JCI116701. PMID: 7690775Free PMC Article

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