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Recurrent Anaplastic Ependymoma

MedGen UID:
1693176
•Concept ID:
C5205651
•
Neoplastic Process

Definition

The reemergence of anaplastic ependymoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Anaplastic Ependymoma

Professional guidelines

PubMed

The evolving role of reirradiation in the management of recurrent brain tumors.
De Pietro R, Zaccaro L, Marampon F, Tini P, De Felice F, Minniti G
J Neurooncol 2023 Sep;164(2):271-286. Epub 2023 Aug 25 doi: 10.1007/s11060-023-04407-2. PMID: 37624529Free PMC Article
Intradural spinal tumors in adults-update on management and outcome.
Ottenhausen M, Ntoulias G, Bodhinayake I, Ruppert FH, Schreiber S, Förschler A, Boockvar JA, Jödicke A
Neurosurg Rev 2019 Jun;42(2):371-388. Epub 2018 Feb 17 doi: 10.1007/s10143-018-0957-x. PMID: 29455369
EANO guidelines for the diagnosis and treatment of ependymal tumors.
Rudà R, Reifenberger G, Frappaz D, Pfister SM, Laprie A, Santarius T, Roth P, Tonn JC, Soffietti R, Weller M, Moyal EC
Neuro Oncol 2018 Mar 27;20(4):445-456. doi: 10.1093/neuonc/nox166. PMID: 29194500Free PMC Article

Recent clinical studies

Etiology

Contralateral Ventriculostomy for Intraoperative Brain Relaxation in Supratentorial Brain Tumors.
Gurjar HK, Mishra S, Garg K
Neurol India 2020 Jan-Feb;68(1):159-162. doi: 10.4103/0028-3886.279710. PMID: 32129267
Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

Diagnosis

Supratentorial extraventricular anaplastic ependymoma with extracranial metastasis.
Pachella LA, Kamiya-Matsuoka C, Lee EL, Olar A, Yung WK
J Clin Neurosci 2015 Mar;22(3):605-7. Epub 2014 Oct 31 doi: 10.1016/j.jocn.2014.09.006. PMID: 25455735Free PMC Article
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Shervington A, Patel R, Lu C, Cruickshanks N, Lea R, Roberts G, Dawson T, Shervington L
Brain Res 2007 Feb 23;1134(1):45-52. Epub 2007 Jan 2 doi: 10.1016/j.brainres.2006.11.093. PMID: 17196947
Cytomorphology of anaplastic ependymoma in a pleural effusion. A case report.
Würtz FG, Dinges HP, Radner H, Kleinert R
Acta Cytol 1995 May-Jun;39(3):577-85. PMID: 7762356

Therapy

Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379
Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.
Patel R, Shervington L, Lea R, Shervington A
Brain Res 2008 Jan 10;1188:173-81. Epub 2007 Oct 26 doi: 10.1016/j.brainres.2007.10.043. PMID: 18021753
Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin.
Rojas-Marcos I, Calvet D, Janoray P, Delattre JY
Neurology 2003 Oct 14;61(7):1019-20. doi: 10.1212/01.wnl.0000082384.15848.fa. PMID: 14557591

Prognosis

Rapid autopsy of a patient with recurrent anaplastic ependymoma.
Lange KR, Fischer C, Rajappa P, Connors S, Pisapia D, Greenfield JP, Beltran H, Rubin M, Mosquera JM, Khakoo Y
Palliat Support Care 2018 Apr;16(2):238-242. Epub 2017 Sep 25 doi: 10.1017/S1478951517000864. PMID: 28942746Free PMC Article
Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma.
Shervington A, Patel R, Lu C, Cruickshanks N, Lea R, Roberts G, Dawson T, Shervington L
Brain Res 2007 Feb 23;1134(1):45-52. Epub 2007 Jan 2 doi: 10.1016/j.brainres.2006.11.093. PMID: 17196947
Long-term control of recurrent anaplastic ependymoma with extracranial metastasis: importance of multiple surgery and stereotactic radiosurgery procedures--case report.
Kinoshita M, Izumoto S, Kagawa N, Hashimoto N, Maruno M, Yoshimine T
Neurol Med Chir (Tokyo) 2004 Dec;44(12):669-73. doi: 10.2176/nmc.44.669. PMID: 15684601

Clinical prediction guides

Contralateral Ventriculostomy for Intraoperative Brain Relaxation in Supratentorial Brain Tumors.
Gurjar HK, Mishra S, Garg K
Neurol India 2020 Jan-Feb;68(1):159-162. doi: 10.4103/0028-3886.279710. PMID: 32129267
Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy.
Murai T, Sato K, Iwabuchi M, Manabe Y, Ogino H, Iwata H, Tatewaki K, Yokota N, Ohta S, Shibamoto Y
Jpn J Radiol 2016 Mar;34(3):211-8. Epub 2015 Dec 18 doi: 10.1007/s11604-015-0511-5. PMID: 26682738
Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

Supplemental Content

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