U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Elevated circulating vitamin B6 concentration

MedGen UID:
1694849
•Concept ID:
C5139369
•
Finding
Synonym: Elevated circulating vitamin B6 level
 
HPO: HP:0032477

Definition

An abnormally increased concentration of vitamin B6 in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated circulating vitamin B6 concentration

Professional guidelines

PubMed

Hypophosphatasia - aetiology, nosology, pathogenesis, diagnosis and treatment.
Whyte MP
Nat Rev Endocrinol 2016 Apr;12(4):233-46. Epub 2016 Feb 19 doi: 10.1038/nrendo.2016.14. PMID: 26893260
Vitamin B6 status and interferon-γ-mediated immune activation in primary hyperparathyroidism.
Christensen MH, Pedersen EK, Nordbø Y, Varhaug JE, Midttun Ø, Ueland PM, Nygård OK, Mellgren G, Lien EA
J Intern Med 2012 Dec;272(6):583-91. Epub 2012 Aug 5 doi: 10.1111/j.1365-2796.2012.02570.x. PMID: 22757621

Recent clinical studies

Therapy

Genetically predicted circulating B vitamins in relation to digestive system cancers.
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Hypophosphatasia in Adults: Clinical Spectrum and Its Association With Genetics and Metabolic Substrates.
Lefever E, Witters P, Gielen E, Vanclooster A, Meersseman W, Morava E, Cassiman D, Laurent MR
J Clin Densitom 2020 Jul-Sep;23(3):340-348. Epub 2018 Dec 21 doi: 10.1016/j.jocd.2018.12.006. PMID: 30655187
Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study.
Kim SJ, Zuchniak A, Sohn KJ, Lubinski J, Demsky R, Eisen A, Akbari MR, Kim YI, Narod SA, Kotsopoulos J
Am J Clin Nutr 2016 Sep;104(3):671-7. Epub 2016 Jul 27 doi: 10.3945/ajcn.116.133470. PMID: 27465373
Homocysteine and renal disease.
van Guldener C, Robinson K
Semin Thromb Hemost 2000;26(3):313-24. doi: 10.1055/s-2000-8407. PMID: 11011849
Homocysteine and coronary atherosclerosis.
Mayer EL, Jacobsen DW, Robinson K
J Am Coll Cardiol 1996 Mar 1;27(3):517-27. doi: 10.1016/0735-1097(95)00508-0. PMID: 8606260

Prognosis

Genetically predicted circulating B vitamins in relation to digestive system cancers.
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
Samarron SL, Miller JW, Cheung AT, Chen PC, Lin X, Zwerdling T, Wun T, Green R
Br J Haematol 2020 Aug;190(3):450-457. Epub 2020 Apr 19 doi: 10.1111/bjh.16618. PMID: 32307711Free PMC Article
Homocysteine and Non-Cardiac Vascular Disease.
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
Plasma folate, vitamin B-6, and vitamin B-12 and breast cancer risk in BRCA1- and BRCA2-mutation carriers: a prospective study.
Kim SJ, Zuchniak A, Sohn KJ, Lubinski J, Demsky R, Eisen A, Akbari MR, Kim YI, Narod SA, Kotsopoulos J
Am J Clin Nutr 2016 Sep;104(3):671-7. Epub 2016 Jul 27 doi: 10.3945/ajcn.116.133470. PMID: 27465373
Homocysteine and renal disease.
van Guldener C, Robinson K
Semin Thromb Hemost 2000;26(3):313-24. doi: 10.1055/s-2000-8407. PMID: 11011849

Clinical prediction guides

Genetically predicted circulating B vitamins in relation to digestive system cancers.
Yuan S, Carter P, Vithayathil M, Kar S, Mason AM, Burgess S, Larsson SC
Br J Cancer 2021 Jun;124(12):1997-2003. Epub 2021 Apr 9 doi: 10.1038/s41416-021-01383-0. PMID: 33837300Free PMC Article
Homocysteine is associated with severity of microvasculopathy in sickle cell disease patients.
Samarron SL, Miller JW, Cheung AT, Chen PC, Lin X, Zwerdling T, Wun T, Green R
Br J Haematol 2020 Aug;190(3):450-457. Epub 2020 Apr 19 doi: 10.1111/bjh.16618. PMID: 32307711Free PMC Article
Homocysteine and Non-Cardiac Vascular Disease.
Katsiki N, Perez-Martinez P, Mikhailidis DP
Curr Pharm Des 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. PMID: 28317478
Vitamin B6 status and interferon-γ-mediated immune activation in primary hyperparathyroidism.
Christensen MH, Pedersen EK, Nordbø Y, Varhaug JE, Midttun Ø, Ueland PM, Nygård OK, Mellgren G, Lien EA
J Intern Med 2012 Dec;272(6):583-91. Epub 2012 Aug 5 doi: 10.1111/j.1365-2796.2012.02570.x. PMID: 22757621
Folate, vitamin B₁₂ and total homocysteine levels in Arab adolescent subjects: reference ranges and potential determinants.
Akanji AO, Thalib L, Al-Isa AN
Nutr Metab Cardiovasc Dis 2012 Oct;22(10):900-6. Epub 2010 Dec 30 doi: 10.1016/j.numecd.2010.10.020. PMID: 21194911

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...