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Stage IIIC2 Cervical Cancer FIGO 2018

MedGen UID:
1697398
•Concept ID:
C5206453
•
Neoplastic Process
Synonym: Stage IIIC2 Cervical Carcinoma FIGO 2018

Definition

Cervical carcinoma with para-aortic lymph node metastasis. (FIGO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIIC2 Cervical Cancer FIGO 2018

Professional guidelines

PubMed

Exploring a Better Adjuvant Treatment for Surgically Treated High-Grade Neuroendocrine Carcinoma of the Cervix.
Wang R, Xiao Y, Ma L, Wu Z, Xia H
Gynecol Obstet Invest 2022;87(6):398-405. Epub 2022 Oct 21 doi: 10.1159/000527661. PMID: 36273460Free PMC Article
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Wright JD, Matsuo K, Huang Y, Tergas AI, Hou JY, Khoury-Collado F, St Clair CM, Ananth CV, Neugut AI, Hershman DL
Obstet Gynecol 2019 Jul;134(1):49-57. doi: 10.1097/AOG.0000000000003311. PMID: 31188324Free PMC Article

Recent clinical studies

Etiology

[(18)F]FDG-PET/CT-based risk stratification in women with locally advanced uterine cervical cancer.
Adam JA, Poel E, van Eck Smit BLF, Mom CH, Stalpers LJA, Laan JJ, Kidd E, Stoker J, Bipat S
BMC Cancer 2024 Apr 23;24(1):513. doi: 10.1186/s12885-024-12232-7. PMID: 38654241Free PMC Article
Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more accurate than FIGO 2009.
Zhang Y, Ding J, Hua K
J Int Med Res 2022 Jan;50(1):3000605211067397. doi: 10.1177/03000605211067397. PMID: 34986672Free PMC Article
Five-fraction HDR brachytherapy in locally advanced cervical cancer: A monocentric experience.
Ogorodniitchouk O, Aunier J, Bousarsar A, Lahmamssi C, Sotton S, Ouaz H, Moreno-Acosta P, Moslemi D, Molekzadehmoghani M, Langrand-Escure J, Magne N, Vallard A
Cancer Radiother 2021 Jul;25(5):463-468. Epub 2021 May 19 doi: 10.1016/j.canrad.2021.03.006. PMID: 34023215
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Wright JD, Matsuo K, Huang Y, Tergas AI, Hou JY, Khoury-Collado F, St Clair CM, Ananth CV, Neugut AI, Hershman DL
Obstet Gynecol 2019 Jul;134(1):49-57. doi: 10.1097/AOG.0000000000003311. PMID: 31188324Free PMC Article

Diagnosis

Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more accurate than FIGO 2009.
Zhang Y, Ding J, Hua K
J Int Med Res 2022 Jan;50(1):3000605211067397. doi: 10.1177/03000605211067397. PMID: 34986672Free PMC Article
Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study.
Kagabu M, Nagasawa T, Tatsuki S, Fukagawa Y, Tomabechi H, Takatori E, Kaido Y, Shoji T, Baba T
Medicina (Kaunas) 2021 May 29;57(6) doi: 10.3390/medicina57060548. PMID: 34072478Free PMC Article
Five-fraction HDR brachytherapy in locally advanced cervical cancer: A monocentric experience.
Ogorodniitchouk O, Aunier J, Bousarsar A, Lahmamssi C, Sotton S, Ouaz H, Moreno-Acosta P, Moslemi D, Molekzadehmoghani M, Langrand-Escure J, Magne N, Vallard A
Cancer Radiother 2021 Jul;25(5):463-468. Epub 2021 May 19 doi: 10.1016/j.canrad.2021.03.006. PMID: 34023215
Magnetic resonance imaging-based validation of the 2018 FIGO staging system in patients treated with definitive radiotherapy for locally advanced cervix cancer.
Kim J, Cho Y, Kim N, Chung SY, Kim JW, Lee IJ, Kim YB
Gynecol Oncol 2021 Mar;160(3):735-741. Epub 2020 Dec 22 doi: 10.1016/j.ygyno.2020.12.012. PMID: 33358037
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Wright JD, Matsuo K, Huang Y, Tergas AI, Hou JY, Khoury-Collado F, St Clair CM, Ananth CV, Neugut AI, Hershman DL
Obstet Gynecol 2019 Jul;134(1):49-57. doi: 10.1097/AOG.0000000000003311. PMID: 31188324Free PMC Article

Therapy

Exploring a Better Adjuvant Treatment for Surgically Treated High-Grade Neuroendocrine Carcinoma of the Cervix.
Wang R, Xiao Y, Ma L, Wu Z, Xia H
Gynecol Obstet Invest 2022;87(6):398-405. Epub 2022 Oct 21 doi: 10.1159/000527661. PMID: 36273460Free PMC Article
Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Long-term outcomes of intensity-modulated radiation therapy (IMRT) and high dose rate brachytherapy as adjuvant therapy after radical hysterectomy for cervical cancer.
Contreras J, Srivastava A, Chundury A, Schwarz JK, Markovina S, Thaker PH, Massad LS, Mutch DG, Powell MA, Grigsby PW, Lin AJ
Int J Gynecol Cancer 2020 Aug;30(8):1157-1161. Epub 2020 Jun 11 doi: 10.1136/ijgc-2020-001412. PMID: 32527770

Prognosis

Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Treatment Strategies and Prognostic Factors of 2018 FIGO Stage IIIC Cervical Cancer: A Review.
Qin F, Pang H, Yu T, Luo Y, Dong Y
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221086403. doi: 10.1177/15330338221086403. PMID: 35341413Free PMC Article
Data from small cell neuroendocrine carcinoma of the cervix: FIGO 2018 staging is more accurate than FIGO 2009.
Zhang Y, Ding J, Hua K
J Int Med Res 2022 Jan;50(1):3000605211067397. doi: 10.1177/03000605211067397. PMID: 34986672Free PMC Article
Magnetic resonance imaging-based validation of the 2018 FIGO staging system in patients treated with definitive radiotherapy for locally advanced cervix cancer.
Kim J, Cho Y, Kim N, Chung SY, Kim JW, Lee IJ, Kim YB
Gynecol Oncol 2021 Mar;160(3):735-741. Epub 2020 Dec 22 doi: 10.1016/j.ygyno.2020.12.012. PMID: 33358037
FIGO Classification 2018: Validation Study in Patients With Locally Advanced Cervix Cancer Treated With Chemoradiation.
Raut A, Chopra S, Mittal P, Patil G, Mahantshetty U, Gurram L, Swamidas J, Ghosh J, Gulia S, Popat P, Deodhar K, Maheshwari A, Gupta S
Int J Radiat Oncol Biol Phys 2020 Dec 1;108(5):1248-1256. Epub 2020 Jul 15 doi: 10.1016/j.ijrobp.2020.07.020. PMID: 32681859

Clinical prediction guides

[(18)F]FDG-PET/CT-based risk stratification in women with locally advanced uterine cervical cancer.
Adam JA, Poel E, van Eck Smit BLF, Mom CH, Stalpers LJA, Laan JJ, Kidd E, Stoker J, Bipat S
BMC Cancer 2024 Apr 23;24(1):513. doi: 10.1186/s12885-024-12232-7. PMID: 38654241Free PMC Article
Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Neoadjuvant Chemotherapy in Locally Advanced Cervical Carcinoma - a Role in Patients with Para-aortic Lymph Node Involvement? A 10-year Institutional Experience.
Green HM, Counsell N, Ward A, McCormack M
Clin Oncol (R Coll Radiol) 2022 Jul;34(7):e281-e290. Epub 2022 Jan 6 doi: 10.1016/j.clon.2021.12.005. PMID: 35000828
Magnetic resonance imaging-based validation of the 2018 FIGO staging system in patients treated with definitive radiotherapy for locally advanced cervix cancer.
Kim J, Cho Y, Kim N, Chung SY, Kim JW, Lee IJ, Kim YB
Gynecol Oncol 2021 Mar;160(3):735-741. Epub 2020 Dec 22 doi: 10.1016/j.ygyno.2020.12.012. PMID: 33358037
Is the revised 2018 FIGO staging system for cervical cancer more prognostic than the 2009 FIGO staging system for women previously staged as IB disease?
Ayhan A, Aslan K, Bulut AN, Akilli H, Öz M, Haberal A, Meydanli MM
Eur J Obstet Gynecol Reprod Biol 2019 Sep;240:209-214. Epub 2019 Jul 6 doi: 10.1016/j.ejogrb.2019.07.002. PMID: 31325847

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