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Advanced Lung Non-Small Cell Carcinoma

MedGen UID:
1701032
Concept ID:
C5206378
Neoplastic Process

Definition

Lung non-small cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Saito Y, Tamaki S, Hirate D, Takada S, Takahashi K, Takekuma Y, Sakakibara-Konishi J, Shimizu Y, Kinoshita I, Sugawara M
Sci Rep 2023 Nov 9;13(1):19457. doi: 10.1038/s41598-023-46775-9. PMID: 37945672Free PMC Article
Li DN, Lu WQ, Yang BW, Zhang LY, Jin B, Wang S, Che XF, Li C, Liu YP, Qu XJ
Front Immunol 2021;12:666909. Epub 2021 Jun 2 doi: 10.3389/fimmu.2021.666909. PMID: 34149702Free PMC Article
Lai LT, Zhan ZY, Feng M, Li F, Lai LF, Zhong LX
Anticancer Drugs 2020 Jul;31(6):637-645. doi: 10.1097/CAD.0000000000000921. PMID: 32058346

Recent clinical studies

Etiology

Chen P, Liu Y, Wen Y, Zhou C
Cancer Commun (Lond) 2022 Oct;42(10):937-970. Epub 2022 Sep 8 doi: 10.1002/cac2.12359. PMID: 36075878Free PMC Article
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236
Postmus PE, Kerr KM, Oudkerk M, Senan S, Waller DA, Vansteenkiste J, Escriu C, Peters S; ESMO Guidelines Committee
Ann Oncol 2017 Jul 1;28(suppl_4):iv1-iv21. doi: 10.1093/annonc/mdx222. PMID: 28881918
Gridelli C, Rossi A, Carbone DP, Guarize J, Karachaliou N, Mok T, Petrella F, Spaggiari L, Rosell R
Nat Rev Dis Primers 2015 May 21;1:15009. doi: 10.1038/nrdp.2015.9. PMID: 27188576
Maghfoor I, Perry MC
Ann Saudi Med 2005 Jan-Feb;25(1):1-12. doi: 10.5144/0256-4947.2005.1. PMID: 15822487Free PMC Article

Diagnosis

Chen P, Liu Y, Wen Y, Zhou C
Cancer Commun (Lond) 2022 Oct;42(10):937-970. Epub 2022 Sep 8 doi: 10.1002/cac2.12359. PMID: 36075878Free PMC Article
Thai AA, Solomon BJ, Sequist LV, Gainor JF, Heist RS
Lancet 2021 Aug 7;398(10299):535-554. Epub 2021 Jul 21 doi: 10.1016/S0140-6736(21)00312-3. PMID: 34273294
Alexander M, Kim SY, Cheng H
Lung 2020 Dec;198(6):897-907. Epub 2020 Nov 11 doi: 10.1007/s00408-020-00407-5. PMID: 33175991Free PMC Article
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236
Postmus PE, Kerr KM, Oudkerk M, Senan S, Waller DA, Vansteenkiste J, Escriu C, Peters S; ESMO Guidelines Committee
Ann Oncol 2017 Jul 1;28(suppl_4):iv1-iv21. doi: 10.1093/annonc/mdx222. PMID: 28881918

Therapy

Chen R, Manochakian R, James L, Azzouqa AG, Shi H, Zhang Y, Zhao Y, Zhou K, Lou Y
J Hematol Oncol 2020 May 24;13(1):58. doi: 10.1186/s13045-020-00881-7. PMID: 32448366Free PMC Article
Herbst RS, Morgensztern D, Boshoff C
Nature 2018 Jan 24;553(7689):446-454. doi: 10.1038/nature25183. PMID: 29364287
Nagasaka M, Gadgeel SM
Expert Rev Anticancer Ther 2018 Jan;18(1):63-70. Epub 2017 Nov 26 doi: 10.1080/14737140.2018.1409624. PMID: 29168933Free PMC Article
Cancer Discov 2015 Jun;5(6):572. Epub 2015 Apr 20 doi: 10.1158/2159-8290.CD-NB2015-057. PMID: 25895920
van Veggel BA, Biesma B, Smit EF
Expert Opin Pharmacother 2015 May;16(7):1021-34. Epub 2015 Mar 22 doi: 10.1517/14656566.2015.1028357. PMID: 25797389

Prognosis

Howlader N, Forjaz G, Mooradian MJ, Meza R, Kong CY, Cronin KA, Mariotto AB, Lowy DR, Feuer EJ
N Engl J Med 2020 Aug 13;383(7):640-649. doi: 10.1056/NEJMoa1916623. PMID: 32786189Free PMC Article
Shaw AT, Solomon BJ, Chiari R, Riely GJ, Besse B, Soo RA, Kao S, Lin CC, Bauer TM, Clancy JS, Thurm H, Martini JF, Peltz G, Abbattista A, Li S, Ou SI
Lancet Oncol 2019 Dec;20(12):1691-1701. Epub 2019 Oct 25 doi: 10.1016/S1470-2045(19)30655-2. PMID: 31669155
Shaw AT, Riely GJ, Bang YJ, Kim DW, Camidge DR, Solomon BJ, Varella-Garcia M, Iafrate AJ, Shapiro GI, Usari T, Wang SC, Wilner KD, Clark JW, Ou SI
Ann Oncol 2019 Jul 1;30(7):1121-1126. doi: 10.1093/annonc/mdz131. PMID: 30980071Free PMC Article
Herbst RS, Morgensztern D, Boshoff C
Nature 2018 Jan 24;553(7689):446-454. doi: 10.1038/nature25183. PMID: 29364287
Postmus PE, Kerr KM, Oudkerk M, Senan S, Waller DA, Vansteenkiste J, Escriu C, Peters S; ESMO Guidelines Committee
Ann Oncol 2017 Jul 1;28(suppl_4):iv1-iv21. doi: 10.1093/annonc/mdx222. PMID: 28881918

Clinical prediction guides

Meyer ML, Fitzgerald BG, Paz-Ares L, Cappuzzo F, Jänne PA, Peters S, Hirsch FR
Lancet 2024 Aug 24;404(10454):803-822. Epub 2024 Aug 6 doi: 10.1016/S0140-6736(24)01029-8. PMID: 39121882
Patel SA, Weiss J
Clin Chest Med 2020 Jun;41(2):237-247. Epub 2020 Apr 16 doi: 10.1016/j.ccm.2020.02.010. PMID: 32402359
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236
Wu SG, Shih JY
Mol Cancer 2018 Feb 19;17(1):38. doi: 10.1186/s12943-018-0777-1. PMID: 29455650Free PMC Article
Bluthgen MV, Besse B
Eur Respir Rev 2015 Dec;24(138):582-93. doi: 10.1183/16000617.00002115. PMID: 26621972Free PMC Article

Recent systematic reviews

Luo Y, Zhang Z, Guo X, Tang X, Li S, Gong G, Gao S, Zhang Y, Lin S
Lung Cancer 2023 Oct;184:107319. Epub 2023 Aug 7 doi: 10.1016/j.lungcan.2023.107319. PMID: 37597303
Wu Y, Verma V, Gay CM, Chen Y, Liang F, Lin Q, Wang J, Zhang W, Hui Z, Zhao M, Wang J, Chang JY
Cancer 2023 Jul 1;129(13):1969-1985. Epub 2023 Mar 30 doi: 10.1002/cncr.34755. PMID: 36994945
Rousseau A, Parisi C, Barlesi F
ESMO Open 2023 Apr;8(2):101184. Epub 2023 Mar 16 doi: 10.1016/j.esmoop.2023.101184. PMID: 36933320Free PMC Article
Liu J, Sauer MA, Hussein SG, Yang J, Tenen DG, Chai L
Genes (Basel) 2021 Aug 24;12(9) doi: 10.3390/genes12091301. PMID: 34573282Free PMC Article
Zhao Y, Liu J, Cai X, Pan Z, Liu J, Yin W, Chen H, Xie Z, Liang H, Wang W, Guo Z, Zhao S, Liang W, He J
BMJ 2019 Oct 7;367:l5460. doi: 10.1136/bmj.l5460. PMID: 31591158Free PMC Article

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