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Advanced Lung Non-Small Cell Carcinoma

MedGen UID:
1701032
Concept ID:
C5206378
Neoplastic Process

Definition

Lung non-small cell carcinoma that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Li DN, Lu WQ, Yang BW, Zhang LY, Jin B, Wang S, Che XF, Li C, Liu YP, Qu XJ
Front Immunol 2021;12:666909. Epub 2021 Jun 2 doi: 10.3389/fimmu.2021.666909. PMID: 34149702Free PMC Article
Lai LT, Zhan ZY, Feng M, Li F, Lai LF, Zhong LX
Anticancer Drugs 2020 Jul;31(6):637-645. doi: 10.1097/CAD.0000000000000921. PMID: 32058346
Zhou Y, Lin Z, Zhang X, Chen C, Zhao H, Hong S, Zhang L
J Immunother Cancer 2019 May 3;7(1):120. doi: 10.1186/s40425-019-0600-6. PMID: 31053172Free PMC Article

Recent clinical studies

Etiology

Chen P, Liu Y, Wen Y, Zhou C
Cancer Commun (Lond) 2022 Oct;42(10):937-970. Epub 2022 Sep 8 doi: 10.1002/cac2.12359. PMID: 36075878Free PMC Article
Saw SPL, Ong BH, Chua KLM, Takano A, Tan DSW
Lancet Oncol 2021 Nov;22(11):e501-e516. doi: 10.1016/S1470-2045(21)00383-1. PMID: 34735819
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236
Wu SG, Shih JY
Mol Cancer 2018 Feb 19;17(1):38. doi: 10.1186/s12943-018-0777-1. PMID: 29455650Free PMC Article
Gridelli C, Rossi A, Carbone DP, Guarize J, Karachaliou N, Mok T, Petrella F, Spaggiari L, Rosell R
Nat Rev Dis Primers 2015 May 21;1:15009. doi: 10.1038/nrdp.2015.9. PMID: 27188576

Diagnosis

Chen P, Liu Y, Wen Y, Zhou C
Cancer Commun (Lond) 2022 Oct;42(10):937-970. Epub 2022 Sep 8 doi: 10.1002/cac2.12359. PMID: 36075878Free PMC Article
Thai AA, Solomon BJ, Sequist LV, Gainor JF, Heist RS
Lancet 2021 Aug 7;398(10299):535-554. Epub 2021 Jul 21 doi: 10.1016/S0140-6736(21)00312-3. PMID: 34273294
Alexander M, Kim SY, Cheng H
Lung 2020 Dec;198(6):897-907. Epub 2020 Nov 11 doi: 10.1007/s00408-020-00407-5. PMID: 33175991Free PMC Article
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236
Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA
Mayo Clin Proc 2008 May;83(5):584-94. doi: 10.4065/83.5.584. PMID: 18452692Free PMC Article

Therapy

Yu HA, Yang JC, Hayashi H, Goto Y, Felip E, Reck M, Vigliotti M, Dong Q, Cantero F, Fan PD, Kanai M, Sternberg DW, Jänne PA
Future Oncol 2023 Jun;19(19):1319-1329. Epub 2023 May 22 doi: 10.2217/fon-2022-1250. PMID: 37212796
Chen R, Manochakian R, James L, Azzouqa AG, Shi H, Zhang Y, Zhao Y, Zhou K, Lou Y
J Hematol Oncol 2020 May 24;13(1):58. doi: 10.1186/s13045-020-00881-7. PMID: 32448366Free PMC Article
Lee SS, Cheah YK
J Immunol Res 2019;2019:3046379. Epub 2019 Feb 13 doi: 10.1155/2019/3046379. PMID: 30944831Free PMC Article
Herbst RS, Morgensztern D, Boshoff C
Nature 2018 Jan 24;553(7689):446-454. doi: 10.1038/nature25183. PMID: 29364287
Nagasaka M, Gadgeel SM
Expert Rev Anticancer Ther 2018 Jan;18(1):63-70. Epub 2017 Nov 26 doi: 10.1080/14737140.2018.1409624. PMID: 29168933Free PMC Article

Prognosis

Howlader N, Forjaz G, Mooradian MJ, Meza R, Kong CY, Cronin KA, Mariotto AB, Lowy DR, Feuer EJ
N Engl J Med 2020 Aug 13;383(7):640-649. doi: 10.1056/NEJMoa1916623. PMID: 32786189Free PMC Article
Shaw AT, Solomon BJ, Chiari R, Riely GJ, Besse B, Soo RA, Kao S, Lin CC, Bauer TM, Clancy JS, Thurm H, Martini JF, Peltz G, Abbattista A, Li S, Ou SI
Lancet Oncol 2019 Dec;20(12):1691-1701. Epub 2019 Oct 25 doi: 10.1016/S1470-2045(19)30655-2. PMID: 31669155
Shaw AT, Riely GJ, Bang YJ, Kim DW, Camidge DR, Solomon BJ, Varella-Garcia M, Iafrate AJ, Shapiro GI, Usari T, Wang SC, Wilner KD, Clark JW, Ou SI
Ann Oncol 2019 Jul 1;30(7):1121-1126. doi: 10.1093/annonc/mdz131. PMID: 30980071Free PMC Article
Herbst RS, Morgensztern D, Boshoff C
Nature 2018 Jan 24;553(7689):446-454. doi: 10.1038/nature25183. PMID: 29364287
Postmus PE, Kerr KM, Oudkerk M, Senan S, Waller DA, Vansteenkiste J, Escriu C, Peters S; ESMO Guidelines Committee
Ann Oncol 2017 Jul 1;28(suppl_4):iv1-iv21. doi: 10.1093/annonc/mdx222. PMID: 28881918

Clinical prediction guides

Yang SR, Schultheis AM, Yu H, Mandelker D, Ladanyi M, Büttner R
Semin Cancer Biol 2022 Sep;84:184-198. Epub 2020 Jul 27 doi: 10.1016/j.semcancer.2020.07.009. PMID: 32730814
Thai AA, Solomon BJ, Sequist LV, Gainor JF, Heist RS
Lancet 2021 Aug 7;398(10299):535-554. Epub 2021 Jul 21 doi: 10.1016/S0140-6736(21)00312-3. PMID: 34273294
Patel SA, Weiss J
Clin Chest Med 2020 Jun;41(2):237-247. Epub 2020 Apr 16 doi: 10.1016/j.ccm.2020.02.010. PMID: 32402359
Arbour KC, Riely GJ
JAMA 2019 Aug 27;322(8):764-774. doi: 10.1001/jama.2019.11058. PMID: 31454018
Duma N, Santana-Davila R, Molina JR
Mayo Clin Proc 2019 Aug;94(8):1623-1640. doi: 10.1016/j.mayocp.2019.01.013. PMID: 31378236

Recent systematic reviews

Zhang M, Fan Y, Nie L, Wang G, Sun K, Cheng Y
Chest 2022 Jun;161(6):1675-1686. Epub 2022 Jan 11 doi: 10.1016/j.chest.2021.12.656. PMID: 35026298
John T, Taylor A, Wang H, Eichinger C, Freeman C, Ahn MJ
Cancer Epidemiol 2022 Feb;76:102080. Epub 2021 Dec 15 doi: 10.1016/j.canep.2021.102080. PMID: 34922050
Zhao Y, Liu J, Cai X, Pan Z, Liu J, Yin W, Chen H, Xie Z, Liang H, Wang W, Guo Z, Zhao S, Liang W, He J
BMJ 2019 Oct 7;367:l5460. doi: 10.1136/bmj.l5460. PMID: 31591158Free PMC Article
Yang Z, Hackshaw A, Feng Q, Fu X, Zhang Y, Mao C, Tang J
Int J Cancer 2017 Jun 15;140(12):2805-2819. Epub 2017 Mar 27 doi: 10.1002/ijc.30691. PMID: 28295308
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

Supplemental Content

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    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

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