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Metastatic malignant neoplasm

MedGen UID:
422475
•Concept ID:
C2939419
•
Neoplastic Process
Synonyms: CA - Secondary cancer; malignant metastatic neoplasm; Metastases; Metastatic cancer; Metastatic Cancer; metastatic cancer; Metastatic malignant disease; Metastatic Malignant Neoplasm; metastatic malignant neoplasm; Metastatic neoplasm; Metastatic neoplasm (disease); metastatic neoplasm, malignant; Secondaries; Secondary cancer; Secondary malignant deposit; Secondary malignant neoplastic disease; Secondary Neoplasm; Secondary tumor; Secondary Tumor; Tumor metastasis
SNOMED CT: Metastatic neoplasm (disease) (128462008); Secondary malignant neoplastic disease (128462008); Metastatic cancer (128462008); CA - Secondary cancer (128462008); Metastases (128462008); Metastatic neoplasm (128462008); Secondaries (128462008); Secondary cancer (128462008); Metastatic malignant disease (128462008); Secondary tumor (128462008); Tumor metastasis (128462008); Secondary malignant deposit (128462008); Metastatic malignant neoplasm (128462008)
 
Monarch Initiative: MONDO:0024880

Definition

A neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic malignant neoplasm

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Diagnosis and treatment of basal cell carcinoma: European consensus-based interdisciplinary guidelines.
Peris K, Fargnoli MC, Garbe C, Kaufmann R, Bastholt L, Seguin NB, Bataille V, Marmol VD, Dummer R, Harwood CA, Hauschild A, Höller C, Haedersdal M, Malvehy J, Middleton MR, Morton CA, Nagore E, Stratigos AJ, Szeimies RM, Tagliaferri L, Trakatelli M, Zalaudek I, Eggermont A, Grob JJ; European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC)
Eur J Cancer 2019 Sep;118:10-34. Epub 2019 Jul 6 doi: 10.1016/j.ejca.2019.06.003. PMID: 31288208
Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr; Endocrine Society
J Clin Endocrinol Metab 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498. PMID: 24893135

Recent clinical studies

Diagnosis

Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas.
Cimino-Mathews A, Subhawong AP, Elwood H, Warzecha HN, Sharma R, Park BH, Taube JM, Illei PB, Argani P
Hum Pathol 2013 Jun;44(6):959-65. Epub 2012 Dec 20 doi: 10.1016/j.humpath.2012.09.005. PMID: 23260325Free PMC Article
Palmar fasciitis and arthritis syndrome associated with metastatic ovarian cancer: a paraneoplastic syndrome.
Nahar IK, Al-Rajhi MS
Gulf J Oncolog 2012 Jul;(12):59-61. PMID: 22773217
Primitive neuroectodermal tumor of the ovary.
Anfinan NM, Sait KH, Al-Maghrabi JA
Saudi Med J 2008 Mar;29(3):444-6. PMID: 18327377

Therapy

Radical surgical cytoreduction of progressive leiomyomatosis peritonealis disseminata: a case report.
Kratz KG, Santillan A, Gu M, Bristow RE
J Reprod Med 2009 Jul;54(7):447-50. PMID: 19691262

Prognosis

Palmar fasciitis and arthritis syndrome associated with metastatic ovarian cancer: a paraneoplastic syndrome.
Nahar IK, Al-Rajhi MS
Gulf J Oncolog 2012 Jul;(12):59-61. PMID: 22773217
Primitive neuroectodermal tumor of the ovary.
Anfinan NM, Sait KH, Al-Maghrabi JA
Saudi Med J 2008 Mar;29(3):444-6. PMID: 18327377

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

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