Refractory High Grade B-Cell Lymphoma

MedGen UID:: 1701508
•Concept ID:: C5205060
•: Neoplastic Process

Synonym:

Refractory High-Grade B-Cell Lymphoma

Definition

High grade B-cell lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRefractory High Grade B-Cell Lymphoma

B-cell lymphoma
- B-cell lymphoma
  - B-cell lymphoma
    - B-cell lymphoma
      - Malignant lymphoma, large B-cell, diffuse
        High grade B-cell lymphoma
        Refractory High Grade B-Cell Lymphoma
        Refractory High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements
        Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements

Professional guidelines

PubMed

Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE).

Yakoub-Agha I, Chabannon C, Bader P, Basak GW, Bonig H, Ciceri F, Corbacioglu S, Duarte RF, Einsele H, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Robinson S, Saccardi R, Sanchez-Guijo F, Snowden JA, Srour M, Styczynski J, Urbano-Ispizua A, Hayden PJ, Kröger N
Haematologica 2020;105(2):297-316. Epub 2020 Jan 31 doi: 10.3324/haematol.2019.229781. PMID: 31753925 Free PMC Article

See all (1)

Recent clinical studies

Therapy

Loncastuximab tesirine in relapsed/refractory high-grade B-cell lymphoma: a subgroup analysis from the LOTIS-2 study.

Alderuccio JP, Ai WZ, Radford J, Solh M, Ardeshna KM, Lunning MA, Hess BT, Zinzani PL, Stathis A, Carlo-Stella C, Hamadani M, Kahl BS, Ungar D, Kilavuz T, Yu E, Qin Y, Caimi PF
Blood Adv 2022 Aug 23;6(16):4736-4739. doi: 10.1182/bloodadvances.2022007782. PMID: 35790100 Free PMC Article

Successful anti-CD19 CAR T-cell therapy in HIV-infected patients with refractory high-grade B-cell lymphoma.

Abramson JS, Irwin KE, Frigault MJ, Dietrich J, McGree B, Jordan JT, Yee AJ, Chen YB, Raje NS, Barnes JA, Davis B
Cancer 2019 Nov 1;125(21):3692-3698. Epub 2019 Sep 10 doi: 10.1002/cncr.32411. PMID: 31503324

See all (2)

MedGen

National Center for Biotechnology Information

Send to:

Refractory High Grade B-Cell Lymphoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Therapy

Supplemental Content

Table of contents

Practice guidelines

Recent activity