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Refractory High Grade B-Cell Lymphoma

MedGen UID:
1701508
•Concept ID:
C5205060
•
Neoplastic Process
Synonym: Refractory High-Grade B-Cell Lymphoma

Definition

High-grade B-cell lymphoma that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE).
Yakoub-Agha I, Chabannon C, Bader P, Basak GW, Bonig H, Ciceri F, Corbacioglu S, Duarte RF, Einsele H, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Robinson S, Saccardi R, Sanchez-Guijo F, Snowden JA, Srour M, Styczynski J, Urbano-Ispizua A, Hayden PJ, Kröger N
Haematologica 2020;105(2):297-316. Epub 2020 Jan 31 doi: 10.3324/haematol.2019.229781. PMID: 31753925Free PMC Article

Recent clinical studies

Therapy

Loncastuximab tesirine in relapsed/refractory high-grade B-cell lymphoma: a subgroup analysis from the LOTIS-2 study.
Alderuccio JP, Ai WZ, Radford J, Solh M, Ardeshna KM, Lunning MA, Hess BT, Zinzani PL, Stathis A, Carlo-Stella C, Hamadani M, Kahl BS, Ungar D, Kilavuz T, Yu E, Qin Y, Caimi PF
Blood Adv 2022 Aug 23;6(16):4736-4739. doi: 10.1182/bloodadvances.2022007782. PMID: 35790100Free PMC Article
Successful anti-CD19 CAR T-cell therapy in HIV-infected patients with refractory high-grade B-cell lymphoma.
Abramson JS, Irwin KE, Frigault MJ, Dietrich J, McGree B, Jordan JT, Yee AJ, Chen YB, Raje NS, Barnes JA, Davis B
Cancer 2019 Nov 1;125(21):3692-3698. Epub 2019 Sep 10 doi: 10.1002/cncr.32411. PMID: 31503324

Prognosis

Chimeric antigen receptor T-cell therapy after COVID-19 in refractory high-grade B-cell lymphoma.
Hayashino K, Seike K, Fujiwara K, Kondo K, Matsubara C, Terao T, Kitamura W, Kamoi C, Fujiwara H, Asada N, Nishimori H, Ennishi D, Fujii K, Fujii N, Matsuoka KI, Maeda Y
Int J Hematol 2024 Apr;119(4):459-464. Epub 2024 Feb 13 doi: 10.1007/s12185-024-03711-5. PMID: 38349446Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

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    • PMC Articles
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