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Refractory Anaplastic Ependymoma

MedGen UID:
1703773
•Concept ID:
C5205652
•
Neoplastic Process

Definition

Anaplastic ependymoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Anaplastic Ependymoma

Professional guidelines

PubMed

Nimotuzumab therapy in the treatment of pediatric central nervous system tumors: single-center experience.
Susam-Sen H, Varan A, Bajin İ, Göçmen R, Aydın B, Yalcin B, Kurucu N, Kutluk T, Bayhan T, Akyuz C
Naunyn Schmiedebergs Arch Pharmacol 2021 Aug;394(8):1769-1777. Epub 2021 Jun 21 doi: 10.1007/s00210-021-02109-y. PMID: 34151393
Nivolumab in the Treatment of Recurrent or Refractory Pediatric Brain Tumors: A Single Institutional Experience.
Gorsi HS, Malicki DM, Barsan V, Tumblin M, Yeh-Nayre L, Milburn M, Elster JD, Crawford JR
J Pediatr Hematol Oncol 2019 May;41(4):e235-e241. doi: 10.1097/MPH.0000000000001339. PMID: 30681550

Recent clinical studies

Etiology

Metronomic Cyclophosphamide With Cisplatin and Bevacizumab for Refractory Anaplastic Ependymoma: A Retrospective Study.
DE Laclos XC, Frappaz D, Ahle G, Bronnimann C, Catry-Thomas I, Joncour A, Ghiringhelli F, Vauleon E
Anticancer Res 2022 Aug;42(8):3863-3867. doi: 10.21873/anticanres.15878. PMID: 35896241
Severe Pneumonia Caused by Methicillin-Resistant Staphylococcus pseudintermedius in an Oncology Patient: Case Report and Literature Review.
Asleh M, Feinstein Y, Lazar I, Rokney A, Baum M, Sagi O, Leibovitz E, Danino D
Microb Drug Resist 2022 Feb;28(2):222-228. Epub 2021 Oct 4 doi: 10.1089/mdr.2020.0469. PMID: 34609906
Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

Diagnosis

Severe Pneumonia Caused by Methicillin-Resistant Staphylococcus pseudintermedius in an Oncology Patient: Case Report and Literature Review.
Asleh M, Feinstein Y, Lazar I, Rokney A, Baum M, Sagi O, Leibovitz E, Danino D
Microb Drug Resist 2022 Feb;28(2):222-228. Epub 2021 Oct 4 doi: 10.1089/mdr.2020.0469. PMID: 34609906

Therapy

Metronomic Cyclophosphamide With Cisplatin and Bevacizumab for Refractory Anaplastic Ependymoma: A Retrospective Study.
DE Laclos XC, Frappaz D, Ahle G, Bronnimann C, Catry-Thomas I, Joncour A, Ghiringhelli F, Vauleon E
Anticancer Res 2022 Aug;42(8):3863-3867. doi: 10.21873/anticanres.15878. PMID: 35896241
Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression.
Komori K, Yanagisawa R, Miyairi Y, Sakashita K, Shiohara M, Fujihara I, Morita D, Nakamura T, Ogiso Y, Sano K, Shirahata M, Fukuoka K, Ichimura K, Shigeta H
Pediatr Blood Cancer 2016 Jan;63(1):152-5. Epub 2015 Aug 25 doi: 10.1002/pbc.25696. PMID: 26305586
Metronomic cyclophosphamide with cisplatin and bevacizumab: a new chemotherapeutic regimen for refractory anaplastic ependymoma.
Lorgis V, Varbedian O, Ghiringhelli F
Anticancer Res 2012 Nov;32(11):5067-70. PMID: 23155280
Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

Prognosis

Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

Clinical prediction guides

Intracavitary chemotherapy (Gliadel) and oral low-dose etoposide for recurrent anaplastic ependymoma.
Sardi I, Sanzo M, Giordano F, Sandri A, Mussa F, Donati PA, Genitori L
Oncol Rep 2008 May;19(5):1219-23. PMID: 18425379

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