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Metastatic Urachal Urothelial Carcinoma

MedGen UID:
1712169
•Concept ID:
C5239335
•
Neoplastic Process
Synonym: Metastatic Bladder Urachal Urothelial Carcinoma

Definition

Bladder urachal urothelial carcinoma that has spread to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Urachal Urothelial Carcinoma

Professional guidelines

PubMed

Clinical outcomes and patterns of population-based management of urachal carcinoma of the bladder: An analysis of the National Cancer Database.
Dursun F, Lim K, Svatek RS, Xu J, El-Zaatari ZM, Wenker EP, Klaassen ZW, Mansour AM, Muhammad T, Efstathiou E, Sonpavde GP, Wallis CJD, Satkunasivam R
Cancer Med 2022 Nov;11(22):4273-4282. Epub 2022 May 4 doi: 10.1002/cam4.4786. PMID: 35509235Free PMC Article
Primary adenocarcinoma of the urinary bladder: differential diagnosis and clinical relevance.
Zhong M, Gersbach E, Rohan SM, Yang XJ
Arch Pathol Lab Med 2013 Mar;137(3):371-81. doi: 10.5858/arpa.2012-0076-RA. PMID: 23451748
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259

Recent clinical studies

Etiology

Clinical outcomes and patterns of population-based management of urachal carcinoma of the bladder: An analysis of the National Cancer Database.
Dursun F, Lim K, Svatek RS, Xu J, El-Zaatari ZM, Wenker EP, Klaassen ZW, Mansour AM, Muhammad T, Efstathiou E, Sonpavde GP, Wallis CJD, Satkunasivam R
Cancer Med 2022 Nov;11(22):4273-4282. Epub 2022 May 4 doi: 10.1002/cam4.4786. PMID: 35509235Free PMC Article
Survival benefit of chemotherapy in a contemporary cohort of metastatic urachal carcinoma.
Flammia RS, Chierigo F, Würnschimmel C, Horlemann B, Hoeh B, Sorce G, Tian Z, Leonardo C, Tilki D, Terrone C, Saad F, Shariat SF, Montorsi F, Chun FK, Gallucci M, Karakiewicz PI
Urol Oncol 2022 Apr;40(4):165.e9-165.e15. Epub 2021 Oct 20 doi: 10.1016/j.urolonc.2021.09.008. PMID: 34686429
Non-urothelial carcinomas of the bladder.
Park S, Reuter VE, Hansel DE
Histopathology 2019 Jan;74(1):97-111. doi: 10.1111/his.13719. PMID: 30565306
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259
Urachal carcinoma: surgical and chemotherapeutic options.
Siefker-Radtke A
Expert Rev Anticancer Ther 2006 Dec;6(12):1715-21. doi: 10.1586/14737140.6.12.1715. PMID: 17181485

Diagnosis

Clinical outcomes and patterns of population-based management of urachal carcinoma of the bladder: An analysis of the National Cancer Database.
Dursun F, Lim K, Svatek RS, Xu J, El-Zaatari ZM, Wenker EP, Klaassen ZW, Mansour AM, Muhammad T, Efstathiou E, Sonpavde GP, Wallis CJD, Satkunasivam R
Cancer Med 2022 Nov;11(22):4273-4282. Epub 2022 May 4 doi: 10.1002/cam4.4786. PMID: 35509235Free PMC Article
Non-urothelial carcinomas of the bladder.
Park S, Reuter VE, Hansel DE
Histopathology 2019 Jan;74(1):97-111. doi: 10.1111/his.13719. PMID: 30565306
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259
Urachal carcinoma: surgical and chemotherapeutic options.
Siefker-Radtke A
Expert Rev Anticancer Ther 2006 Dec;6(12):1715-21. doi: 10.1586/14737140.6.12.1715. PMID: 17181485
From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation.
Wong-You-Cheong JJ, Woodward PJ, Manning MA, Sesterhenn IA
Radiographics 2006 Mar-Apr;26(2):553-80. doi: 10.1148/rg.262055172. PMID: 16549617

Therapy

Final Results From a Phase I Trial and Expansion Cohorts of Cabozantinib and Nivolumab Alone or With Ipilimumab for Advanced/Metastatic Genitourinary Tumors.
Apolo AB, Girardi DM, Niglio SA, Nadal R, Kydd AR, Simon N, Ley L, Cordes LM, Chandran E, Steinberg SM, Lee S, Lee MJ, Rastogi S, Sato N, Cao L, Banday AR, Boudjadi S, Merino MJ, Toubaji A, Akbulut D, Redd B, Bagheri H, Costello R, Gurram S, Agarwal PK, Chalfin HJ, Valera V, Streicher H, Wright JJ, Sharon E, Figg WD, Parnes HL, Gulley JL, Saraiya B, Pal SK, Quinn D, Stein MN, Lara PN, Bottaro DP, Mortazavi A
J Clin Oncol 2024 Sep 1;42(25):3033-3046. Epub 2024 Jul 2 doi: 10.1200/JCO.23.02233. PMID: 38954785Free PMC Article
Estimation of the incidence of urachal cancer: A systematic review and meta-analysis of registry-based studies.
Olah C, Kubik A, Mátrai P, Engh MA, Barna V, Hegyi P, Reis H, Nyirády P, Szarvas T
Urol Oncol 2024 Jul;42(7):221.e1-221.e7. Epub 2024 Apr 15 doi: 10.1016/j.urolonc.2024.03.011. PMID: 38627107
Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma.
Mäkelä R, Arjonen A, Härmä V, Rintanen N, Paasonen L, Paprotka T, Rönsch K, Kuopio T, Kononen J, Rantala JK
BMC Cancer 2020 Jun 23;20(1):590. doi: 10.1186/s12885-020-07092-w. PMID: 32576176Free PMC Article
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259
Urachal carcinoma: surgical and chemotherapeutic options.
Siefker-Radtke A
Expert Rev Anticancer Ther 2006 Dec;6(12):1715-21. doi: 10.1586/14737140.6.12.1715. PMID: 17181485

Prognosis

Estimation of the incidence of urachal cancer: A systematic review and meta-analysis of registry-based studies.
Olah C, Kubik A, Mátrai P, Engh MA, Barna V, Hegyi P, Reis H, Nyirády P, Szarvas T
Urol Oncol 2024 Jul;42(7):221.e1-221.e7. Epub 2024 Apr 15 doi: 10.1016/j.urolonc.2024.03.011. PMID: 38627107
Non-urothelial carcinomas of the bladder.
Park S, Reuter VE, Hansel DE
Histopathology 2019 Jan;74(1):97-111. doi: 10.1111/his.13719. PMID: 30565306
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259
Urachal carcinoma: surgical and chemotherapeutic options.
Siefker-Radtke A
Expert Rev Anticancer Ther 2006 Dec;6(12):1715-21. doi: 10.1586/14737140.6.12.1715. PMID: 17181485
From the Archives of the AFIP: neoplasms of the urinary bladder: radiologic-pathologic correlation.
Wong-You-Cheong JJ, Woodward PJ, Manning MA, Sesterhenn IA
Radiographics 2006 Mar-Apr;26(2):553-80. doi: 10.1148/rg.262055172. PMID: 16549617

Clinical prediction guides

Survival benefit of chemotherapy in a contemporary cohort of metastatic urachal carcinoma.
Flammia RS, Chierigo F, Würnschimmel C, Horlemann B, Hoeh B, Sorce G, Tian Z, Leonardo C, Tilki D, Terrone C, Saad F, Shariat SF, Montorsi F, Chun FK, Gallucci M, Karakiewicz PI
Urol Oncol 2022 Apr;40(4):165.e9-165.e15. Epub 2021 Oct 20 doi: 10.1016/j.urolonc.2021.09.008. PMID: 34686429
Urachal carcinoma: A case of a rare neoplasm.
Moreira I, Coelho S, Rodrigues Â, Patrão AS, Maurício MJ
Curr Probl Cancer 2021 Dec;45(6):100711. Epub 2021 Jan 28 doi: 10.1016/j.currproblcancer.2021.100711. PMID: 33541722
A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.
Kaur S, Gupta A, Gulwani HV
Indian J Cancer 2019 Jul-Sep;56(3):254-260. doi: 10.4103/ijc.IJC_459_17. PMID: 31389390
Urachal adenocarcinoma: a clinician's guide for treatment.
Siefker-Radtke A
Semin Oncol 2012 Oct;39(5):619-24. doi: 10.1053/j.seminoncol.2012.08.011. PMID: 23040259
Urachal carcinoma: surgical and chemotherapeutic options.
Siefker-Radtke A
Expert Rev Anticancer Ther 2006 Dec;6(12):1715-21. doi: 10.1586/14737140.6.12.1715. PMID: 17181485

Recent systematic reviews

Estimation of the incidence of urachal cancer: A systematic review and meta-analysis of registry-based studies.
Olah C, Kubik A, Mátrai P, Engh MA, Barna V, Hegyi P, Reis H, Nyirády P, Szarvas T
Urol Oncol 2024 Jul;42(7):221.e1-221.e7. Epub 2024 Apr 15 doi: 10.1016/j.urolonc.2024.03.011. PMID: 38627107

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