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Bladder neoplasm

MedGen UID:
594
Concept ID:
C0005695
Neoplastic Process
Synonyms: Bladder Neoplasm; Bladder Neoplasms; Bladder Tumor; Bladder Tumors; Neoplasm, Bladder; Neoplasm, Urinary Bladder; Neoplasms, Bladder; Tumor, Bladder; Tumors, Bladder; Urinary Bladder Neoplasm; Urinary Bladder Neoplasms
SNOMED CT: Tumor of urinary bladder (126885006); Neoplasm of bladder (126885006); NGB - New growth of bladder (126885006)
 
HPO: HP:0009725
Monarch Initiative: MONDO:0004987

Definition

The presence of a neoplasm of the urinary bladder. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBladder neoplasm

Conditions with this feature

Malignant tumor of urinary bladder
MedGen UID:
14150
Concept ID:
C0005684
Neoplastic Process
A primary or metastatic malignant neoplasm involving the bladder.
Familial adenomatous polyposis 3
MedGen UID:
902388
Concept ID:
C4225157
Disease or Syndrome
NTHL1 tumor syndrome is characterized by an increased lifetime risk for colorectal cancer (CRC), breast cancer, and colorectal polyposis. Colorectal polyps can be adenomatous, hyperplastic, and/or sessile serrated. Duodenal polyposis has also been reported. Additional cancers reported in individuals with NTHL1 tumor syndrome include endometrial cancer, cervical cancer, urothelial carcinoma of the bladder, meningiomas, unspecified brain tumors, basal cell carcinomas, head and neck squamous cell carcinomas, and hematologic malignancies. The cumulative lifetime risk of developing extracolonic cancer by age 60 years has been estimated at 35% to 78%.

Professional guidelines

PubMed

Sforza S, Tuccio A, Zammarchi L, Verrienti P, Rinaldi F, Tilli M, Di Maida F, Mari A, Masieri L, Carini M, Bartoloni A, Minervini A
Actas Urol Esp (Engl Ed) 2021 May;45(4):309-319. Epub 2021 Mar 5 doi: 10.1016/j.acuro.2020.03.016. PMID: 33685664
Bansal P, Dwivedi DK, Hatwal D, Sharma P, Gupta V, Goyal S, Maithani M
Anticancer Agents Med Chem 2021;21(18):2478-2486. doi: 10.2174/1871520621666210121093852. PMID: 33475078
Young MJ, Soloway MS
Urol Clin North Am 1998 Nov;25(4):603-11. doi: 10.1016/s0094-0143(05)70051-3. PMID: 10026769

Curated

A 20 gene model for predicting nodal involvement in bladder cancer patients with muscle invasive tumors.

Recent clinical studies

Etiology

Galiya R, Stanislav K, Jawdat J, Benjamin H, Boris C
J Pediatr Urol 2022 Dec;18(6):833.e1-833.e4. Epub 2022 Jun 30 doi: 10.1016/j.jpurol.2022.06.026. PMID: 35871900
Ahmadinezhad M, Arshadi M, Hesari E, Sharafoddin M, Azizi H, Khodamoradi F
Epidemiol Health 2022;44:e2022050. Epub 2022 May 30 doi: 10.4178/epih.e2022050. PMID: 35638225Free PMC Article
Ma J, Black PC
Hematol Oncol Clin North Am 2021 Jun;35(3):495-511. Epub 2021 Apr 16 doi: 10.1016/j.hoc.2021.02.002. PMID: 33958147
Klap J, Schmid M, Loughlin KR
Can J Urol 2014 Aug;21(4):7335-43. PMID: 25171275
Cheng L, Montironi R, Davidson DD, Lopez-Beltran A
Mod Pathol 2009 Jun;22 Suppl 2:S70-95. doi: 10.1038/modpathol.2009.1. PMID: 19494855

Diagnosis

Galiya R, Stanislav K, Jawdat J, Benjamin H, Boris C
J Pediatr Urol 2022 Dec;18(6):833.e1-833.e4. Epub 2022 Jun 30 doi: 10.1016/j.jpurol.2022.06.026. PMID: 35871900
Klap J, Schmid M, Loughlin KR
Can J Urol 2014 Aug;21(4):7335-43. PMID: 25171275
Dighe MK, Bhargava P, Wright J
J Comput Assist Tomogr 2011 Jul-Aug;35(4):411-24. doi: 10.1097/RCT.0b013e31821c2e9d. PMID: 21765295
Cheng L, Montironi R, Davidson DD, Lopez-Beltran A
Mod Pathol 2009 Jun;22 Suppl 2:S70-95. doi: 10.1038/modpathol.2009.1. PMID: 19494855
Hayashi N, Wada T, Kiyota H, Ueda M, Oishi Y
Int J Urol 2003 Sep;10(9):498-500. doi: 10.1046/j.1442-2042.2003.00669.x. PMID: 12941130

Therapy

Ahmadinezhad M, Arshadi M, Hesari E, Sharafoddin M, Azizi H, Khodamoradi F
Epidemiol Health 2022;44:e2022050. Epub 2022 May 30 doi: 10.4178/epih.e2022050. PMID: 35638225Free PMC Article
Ma J, Black PC
Hematol Oncol Clin North Am 2021 Jun;35(3):495-511. Epub 2021 Apr 16 doi: 10.1016/j.hoc.2021.02.002. PMID: 33958147
Rodrigues Pessoa R, Mueller AC, Boxley P, Flaig TW, Piper C, Konety B, Yu JB, Gershman B, Kukreja J, Kim SP
Urol Oncol 2021 Nov;39(11):786.e1-786.e8. Epub 2021 Apr 10 doi: 10.1016/j.urolonc.2021.03.009. PMID: 33846085
Boulanger M, Tual S, Lemarchand C, Guizard AV, Velten M, Marcotullio E, Baldi I, Clin B, Lebailly P
Int Arch Occup Environ Health 2017 Feb;90(2):169-178. Epub 2016 Nov 4 doi: 10.1007/s00420-016-1182-y. PMID: 27815726
Klap J, Schmid M, Loughlin KR
Can J Urol 2014 Aug;21(4):7335-43. PMID: 25171275

Prognosis

Galiya R, Stanislav K, Jawdat J, Benjamin H, Boris C
J Pediatr Urol 2022 Dec;18(6):833.e1-833.e4. Epub 2022 Jun 30 doi: 10.1016/j.jpurol.2022.06.026. PMID: 35871900
Sanguedolce F, Russo D, Mancini V, Selvaggio O, Calò B, Carrieri G, Cormio L
Urol Int 2019;102(3):249-261. Epub 2018 Nov 21 doi: 10.1159/000494359. PMID: 30463072
Ngo B, Perera M, Papa N, Bolton D, Sengupta S
BJU Int 2017 May;119 Suppl 5:10-18. doi: 10.1111/bju.13821. PMID: 28544294
Guancial EA, Bellmunt J, Yeh S, Rosenberg JE, Berman DM
Urol Oncol 2014 Jan;32(1):41.e31-40. Epub 2013 Aug 2 doi: 10.1016/j.urolonc.2013.04.014. PMID: 23911686Free PMC Article
Cheng L, Montironi R, Davidson DD, Lopez-Beltran A
Mod Pathol 2009 Jun;22 Suppl 2:S70-95. doi: 10.1038/modpathol.2009.1. PMID: 19494855

Clinical prediction guides

Sanguedolce F, Russo D, Mancini V, Selvaggio O, Calò B, Carrieri G, Cormio L
Urol Int 2019;102(3):249-261. Epub 2018 Nov 21 doi: 10.1159/000494359. PMID: 30463072
Koga F, Takemura K, Fukushima H
Int J Mol Sci 2018 Sep 15;19(9) doi: 10.3390/ijms19092777. PMID: 30223570Free PMC Article
Ngo B, Perera M, Papa N, Bolton D, Sengupta S
BJU Int 2017 May;119 Suppl 5:10-18. doi: 10.1111/bju.13821. PMID: 28544294
Guancial EA, Bellmunt J, Yeh S, Rosenberg JE, Berman DM
Urol Oncol 2014 Jan;32(1):41.e31-40. Epub 2013 Aug 2 doi: 10.1016/j.urolonc.2013.04.014. PMID: 23911686Free PMC Article
Cheng L, Montironi R, Davidson DD, Lopez-Beltran A
Mod Pathol 2009 Jun;22 Suppl 2:S70-95. doi: 10.1038/modpathol.2009.1. PMID: 19494855

Recent systematic reviews

Ahmadinezhad M, Arshadi M, Hesari E, Sharafoddin M, Azizi H, Khodamoradi F
Epidemiol Health 2022;44:e2022050. Epub 2022 May 30 doi: 10.4178/epih.e2022050. PMID: 35638225Free PMC Article
Rodrigues Pessoa R, Mueller AC, Boxley P, Flaig TW, Piper C, Konety B, Yu JB, Gershman B, Kukreja J, Kim SP
Urol Oncol 2021 Nov;39(11):786.e1-786.e8. Epub 2021 Apr 10 doi: 10.1016/j.urolonc.2021.03.009. PMID: 33846085
Ren J, Yang Y, Peng T, Xu D
Biosci Rep 2020 Sep 30;40(9) doi: 10.1042/BSR20202127. PMID: 32797169Free PMC Article
Ngo B, Perera M, Papa N, Bolton D, Sengupta S
BJU Int 2017 May;119 Suppl 5:10-18. doi: 10.1111/bju.13821. PMID: 28544294
Turner RM, Kwok CS, Chen-Turner C, Maduakor CA, Singh S, Loke YK
Br J Clin Pharmacol 2014 Aug;78(2):258-73. doi: 10.1111/bcp.12306. PMID: 24325197Free PMC Article

Supplemental Content

Table of contents

    Genetic Testing Registry

    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • Dancik et al., 2011
      A 20 gene model for predicting nodal involvement in bladder cancer patients with muscle invasive tumors.

    Consumer resources

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