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Refractory Anaplastic Oligodendroglioma

MedGen UID:
1716709
•Concept ID:
C5239365
•
Neoplastic Process

Definition

An anaplastic oligodendroglioma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Anaplastic Oligodendroglioma

Recent clinical studies

Etiology

Eslicarbazepine in patients with brain tumor-related epilepsy: a single-center experience.
Zoccarato M, Basile AM, Padovan M, Caccese M, Zagonel V, Lombardi G
Int J Neurosci 2021 Sep;131(9):879-884. Epub 2020 May 3 doi: 10.1080/00207454.2020.1759590. PMID: 32316814
Epilepsy surgery following brain tumor resection in children.
Tian AG, Edwards MS, Williams NJ, Olson DM
J Neurosurg Pediatr 2011 Mar;7(3):229-34. doi: 10.3171/2010.12.PEDS10293. PMID: 21361758
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
Guillaume DJ, Doolittle ND, Gahramanov S, Hedrick NA, Delashaw JB, Neuwelt EA
Neurosurgery 2010 Jan;66(1):48-58; discussion 58. doi: 10.1227/01.. PMID: 20023537Free PMC Article
Safety and toxicity of intrathecal liposomal cytarabine (Depocyte) in children and adolescents with recurrent or refractory brain tumors: a multi-institutional retrospective study.
Benesch M, Siegler N, Hoff Kv, Lassay L, Kropshofer G, Müller H, Sommer C, Rutkowski S, Fleischhack G, Urban C
Anticancer Drugs 2009 Oct;20(9):794-9. doi: 10.1097/CAD.0b013e32832f4abe. PMID: 19617818
Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma.
Chamberlain MC, Johnston S
Cancer 2009 Apr 15;115(8):1734-43. doi: 10.1002/cncr.24179. PMID: 19197992

Diagnosis

Symptomatic Spinal Seeding Metastasis of a Low-grade Oligodendroglioma.
Keskin E, Aydin HA, Bahadir B, Simsek K, Kalayci M
J Coll Physicians Surg Pak 2022 Oct;32(10):1347-1349. doi: 10.29271/jcpsp.2022.10.1347. PMID: 36205285
Multinodular and vacuolating neuronal tumor of the cerebrum. A rare entity. New case and review of the literature.
Gonzalez-Quarante LH, Ruiz-Juretschke F, Sola Vendrell E, Gil de Sagredo Del Corral OL, Agarwal V, Garcia-Leal R
Neurocirugia (Astur : Engl Ed) 2018 Jan-Feb;29(1):44-55. Epub 2017 Oct 28 doi: 10.1016/j.neucir.2017.08.003. PMID: 29111096
Cranial and spinal oligodendrogliomatosis: a case report and review of the literature.
Lee SL, Wong A, Stadler JA 3rd, McClendon J Jr, Smith TR, Wadhwani NR, Tomita T
Childs Nerv Syst 2015 Jan;31(1):147-53. Epub 2014 Aug 26 doi: 10.1007/s00381-014-2506-4. PMID: 25155447
Future directions for temozolomide therapy.
Yung WK
Semin Oncol 2001 Aug;28(4 Suppl 13):43-6. doi: 10.1016/s0093-7754(01)90070-3. PMID: 11550138
Meningioangiomatosis. A comprehensive analysis of clinical and laboratory features.
Wiebe S, Munoz DG, Smith S, Lee DH
Brain 1999 Apr;122 ( Pt 4):709-26. doi: 10.1093/brain/122.4.709. PMID: 10219783

Therapy

Eslicarbazepine in patients with brain tumor-related epilepsy: a single-center experience.
Zoccarato M, Basile AM, Padovan M, Caccese M, Zagonel V, Lombardi G
Int J Neurosci 2021 Sep;131(9):879-884. Epub 2020 May 3 doi: 10.1080/00207454.2020.1759590. PMID: 32316814
Bevacizumab and other novel therapies for recurrent oligodendroglial tumors.
Grimm SA, Chamberlain MC
CNS Oncol 2015;4(5):333-9. Epub 2015 Oct 28 doi: 10.2217/cns.15.27. PMID: 26509217Free PMC Article
Temozolomide and unusual indications: review of literature.
Tatar Z, Thivat E, Planchat E, Gimbergues P, Gadea E, Abrial C, Durando X
Cancer Treat Rev 2013 Apr;39(2):125-35. Epub 2012 Jul 19 doi: 10.1016/j.ctrv.2012.06.002. PMID: 22818211
Bevacizumab for recurrent alkylator-refractory anaplastic oligodendroglioma.
Chamberlain MC, Johnston S
Cancer 2009 Apr 15;115(8):1734-43. doi: 10.1002/cncr.24179. PMID: 19197992
Future directions for temozolomide therapy.
Yung WK
Semin Oncol 2001 Aug;28(4 Suppl 13):43-6. doi: 10.1016/s0093-7754(01)90070-3. PMID: 11550138

Prognosis

Sustained response to erlotinib and rapamycin in a patient with pediatric anaplastic oligodendroglioma.
Geben LC, Mobley BC, Brockman AA, Pastakia D, Naftel R, Ihrie RA, Esbenshade AJ
Pediatr Blood Cancer 2021 Jan;68(1):e28750. Epub 2020 Oct 1 doi: 10.1002/pbc.28750. PMID: 33001573Free PMC Article
Cranial and spinal oligodendrogliomatosis: a case report and review of the literature.
Lee SL, Wong A, Stadler JA 3rd, McClendon J Jr, Smith TR, Wadhwani NR, Tomita T
Childs Nerv Syst 2015 Jan;31(1):147-53. Epub 2014 Aug 26 doi: 10.1007/s00381-014-2506-4. PMID: 25155447
Sudden death from diffuse leptomeningeal oligodendrogliomatosis.
Reynolds RM, Boswell E, Hulette CM, Cummings TJ, Haglund MM, Boswell E, Hulette CM, Cumm Ings TJ, Haglund MM
J Neurosurg Spine 2011 Dec;15(6):625-9. Epub 2011 Sep 2 doi: 10.3171/2011.7.SPINE10728. PMID: 21888480
Do epileptic seizures predict outcome in patients with oligodendroglioma?
Mirsattari SM, Chong JJ, Hammond RR, Megyesi JF, Macdonald DR, Lee DH, Cairncross JG
Epilepsy Res 2011 Mar;94(1-2):39-44. Epub 2011 Feb 18 doi: 10.1016/j.eplepsyres.2011.01.001. PMID: 21315558
Intra-arterial chemotherapy with osmotic blood-brain barrier disruption for aggressive oligodendroglial tumors: results of a phase I study.
Guillaume DJ, Doolittle ND, Gahramanov S, Hedrick NA, Delashaw JB, Neuwelt EA
Neurosurgery 2010 Jan;66(1):48-58; discussion 58. doi: 10.1227/01.. PMID: 20023537Free PMC Article

Clinical prediction guides

Symptomatic Spinal Seeding Metastasis of a Low-grade Oligodendroglioma.
Keskin E, Aydin HA, Bahadir B, Simsek K, Kalayci M
J Coll Physicians Surg Pak 2022 Oct;32(10):1347-1349. doi: 10.29271/jcpsp.2022.10.1347. PMID: 36205285
Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial.
Fangusaro J, Mitchell DA, Kocak M, Robinson GW, Baxter PA, Hwang EI, Huang J, Onar-Thomas A, Dunkel IJ, Fouladi M, Warren KE
Pediatr Blood Cancer 2021 Feb;68(2):e28756. Epub 2020 Oct 7 doi: 10.1002/pbc.28756. PMID: 33025730Free PMC Article
Do epileptic seizures predict outcome in patients with oligodendroglioma?
Mirsattari SM, Chong JJ, Hammond RR, Megyesi JF, Macdonald DR, Lee DH, Cairncross JG
Epilepsy Res 2011 Mar;94(1-2):39-44. Epub 2011 Feb 18 doi: 10.1016/j.eplepsyres.2011.01.001. PMID: 21315558
Safety and toxicity of intrathecal liposomal cytarabine (Depocyte) in children and adolescents with recurrent or refractory brain tumors: a multi-institutional retrospective study.
Benesch M, Siegler N, Hoff Kv, Lassay L, Kropshofer G, Müller H, Sommer C, Rutkowski S, Fleischhack G, Urban C
Anticancer Drugs 2009 Oct;20(9):794-9. doi: 10.1097/CAD.0b013e32832f4abe. PMID: 19617818
New-onset psychogenic seizures after intracranial neurosurgery.
Reuber M, Kral T, Kurthen M, Elger CE
Acta Neurochir (Wien) 2002 Sep;144(9):901-7; discussion 907. doi: 10.1007/s00701-002-0993-7. PMID: 12376771

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