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Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

MedGen UID:
1718561
Concept ID:
C5237018
Neoplastic Process

Definition

Diffuse large B-cell lymphoma, not otherwise specified that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Poletto S, Novo M, Paruzzo L, Frascione PMM, Vitolo U
Cancer Treat Rev 2022 Nov;110:102443. Epub 2022 Jul 31 doi: 10.1016/j.ctrv.2022.102443. PMID: 35933930
Goldfinger M, Cooper DL
Clin Lymphoma Myeloma Leuk 2022 Mar;22(3):140-148. Epub 2021 Sep 20 doi: 10.1016/j.clml.2021.09.011. PMID: 34666950
Susanibar-Adaniya S, Barta SK
Am J Hematol 2021 May 1;96(5):617-629. Epub 2021 Mar 19 doi: 10.1002/ajh.26151. PMID: 33661537Free PMC Article

Recent clinical studies

Etiology

Carlund O, Thörn E, Osterman P, Fors M, Dernstedt A, Forsell MNE, Erlanson M, Landfors M, Degerman S, Hultdin M
Clin Epigenetics 2024 May 21;16(1):68. doi: 10.1186/s13148-024-01680-4. PMID: 38773655Free PMC Article
Dunleavy K
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):157-163. doi: 10.1182/hematology.2021000247. PMID: 34889402Free PMC Article
Lurain K, Ramaswami R, Mangusan R, Widell A, Ekwede I, George J, Ambinder R, Cheever M, Gulley JL, Goncalves PH, Wang HW, Uldrick TS, Yarchoan R
J Immunother Cancer 2021 Feb;9(2) doi: 10.1136/jitc-2020-002097. PMID: 33608378Free PMC Article
Bledsoe JR, Redd RA, Hasserjian RP, Soumerai JD, Nishino HT, Boyer DF, Ferry JA, Zukerberg LR, Harris NL, Abramson JS, Sohani AR
Am J Hematol 2016 Oct;91(10):E436-41. Epub 2016 Aug 4 doi: 10.1002/ajh.24485. PMID: 27419920
Song KW, Mollee P, Keating A, Crump M
Br J Haematol 2003 Mar;120(6):978-85. doi: 10.1046/j.1365-2141.2003.04203.x. PMID: 12648067

Diagnosis

Slak TC, Miceska S, Gasljevic G, Boltezar L, Kloboves-Prevodnik V
Radiol Oncol 2024 Mar 1;58(1):99-109. Epub 2024 Feb 21 doi: 10.2478/raon-2024-0010. PMID: 38378036Free PMC Article
Bledsoe JR, Redd RA, Hasserjian RP, Soumerai JD, Nishino HT, Boyer DF, Ferry JA, Zukerberg LR, Harris NL, Abramson JS, Sohani AR
Am J Hematol 2016 Oct;91(10):E436-41. Epub 2016 Aug 4 doi: 10.1002/ajh.24485. PMID: 27419920
Abramson JS, Feldman T, Kroll-Desrosiers AR, Muffly LS, Winer E, Flowers CR, Lansigan F, Nabhan C, Nastoupil LJ, Nath R, Goy A, Castillo JJ, Jagadeesh D, Woda B, Rosen ST, Smith SM, Evens AM
Ann Oncol 2014 Nov;25(11):2211-2217. Epub 2014 Sep 5 doi: 10.1093/annonc/mdu443. PMID: 25193992Free PMC Article

Therapy

Frampton JE
Drugs 2023 Sep;83(14):1331-1340. doi: 10.1007/s40265-023-01930-4. PMID: 37597091
Kharfan-Dabaja MA, Yassine F, Moustafa MA, Iqbal M, Murthy H
Hematol Oncol Stem Cell Ther 2022 Dec 23;15(4):168-175. doi: 10.1016/j.hemonc.2021.09.004. PMID: 34699774
Dunleavy K
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):157-163. doi: 10.1182/hematology.2021000247. PMID: 34889402Free PMC Article
Lee A
Drugs 2021 Jul;81(10):1229-1233. doi: 10.1007/s40265-021-01550-w. PMID: 34143407
Hoy SM
Drugs 2020 Nov;80(16):1731-1737. doi: 10.1007/s40265-020-01405-w. PMID: 32946059

Prognosis

Carlund O, Thörn E, Osterman P, Fors M, Dernstedt A, Forsell MNE, Erlanson M, Landfors M, Degerman S, Hultdin M
Clin Epigenetics 2024 May 21;16(1):68. doi: 10.1186/s13148-024-01680-4. PMID: 38773655Free PMC Article
Slak TC, Miceska S, Gasljevic G, Boltezar L, Kloboves-Prevodnik V
Radiol Oncol 2024 Mar 1;58(1):99-109. Epub 2024 Feb 21 doi: 10.2478/raon-2024-0010. PMID: 38378036Free PMC Article
Hoy SM
Drugs 2020 Nov;80(16):1731-1737. doi: 10.1007/s40265-020-01405-w. PMID: 32946059
Umakanthan JM, Iqbal J, Batlevi CL, Bouska A, Smith LM, Shostrom V, Nutsch H, William BM, Gregory Bociek R, Lunning M, Bierman P, Younes A, Armitage JO, Vose JM
Br J Haematol 2019 Mar;184(5):744-752. Epub 2018 Dec 5 doi: 10.1111/bjh.15702. PMID: 30520026Free PMC Article
Bledsoe JR, Redd RA, Hasserjian RP, Soumerai JD, Nishino HT, Boyer DF, Ferry JA, Zukerberg LR, Harris NL, Abramson JS, Sohani AR
Am J Hematol 2016 Oct;91(10):E436-41. Epub 2016 Aug 4 doi: 10.1002/ajh.24485. PMID: 27419920

Clinical prediction guides

Carlund O, Thörn E, Osterman P, Fors M, Dernstedt A, Forsell MNE, Erlanson M, Landfors M, Degerman S, Hultdin M
Clin Epigenetics 2024 May 21;16(1):68. doi: 10.1186/s13148-024-01680-4. PMID: 38773655Free PMC Article
Slak TC, Miceska S, Gasljevic G, Boltezar L, Kloboves-Prevodnik V
Radiol Oncol 2024 Mar 1;58(1):99-109. Epub 2024 Feb 21 doi: 10.2478/raon-2024-0010. PMID: 38378036Free PMC Article
Bledsoe JR, Redd RA, Hasserjian RP, Soumerai JD, Nishino HT, Boyer DF, Ferry JA, Zukerberg LR, Harris NL, Abramson JS, Sohani AR
Am J Hematol 2016 Oct;91(10):E436-41. Epub 2016 Aug 4 doi: 10.1002/ajh.24485. PMID: 27419920
Abramson JS, Feldman T, Kroll-Desrosiers AR, Muffly LS, Winer E, Flowers CR, Lansigan F, Nabhan C, Nastoupil LJ, Nath R, Goy A, Castillo JJ, Jagadeesh D, Woda B, Rosen ST, Smith SM, Evens AM
Ann Oncol 2014 Nov;25(11):2211-2217. Epub 2014 Sep 5 doi: 10.1093/annonc/mdu443. PMID: 25193992Free PMC Article

Supplemental Content

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