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Focal non-convulsive status epilepticus with impairment of consciousness

MedGen UID:
1719906
•Concept ID:
C5397866
•
Disease or Syndrome
Synonym: Focal non-convulsive status epilepticus with impairment of awareness
 
HPO: HP:0032861

Definition

Focal non-convulsive status epilepticus with impairment of consciousness is a type of focal non-convulsive status epilepticus in which awareness is impaired. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal non-convulsive status epilepticus with impairment of consciousness

Professional guidelines

PubMed

Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.
Caraballo RH, Reyes Valenzuela G, Fortini S, Espeche A, Gamboni B, Silva W, Semprino M, Fasulo L, Chacón S, Gallo A, Galicchio S, Cachia P
Epilepsy Behav 2023 Jun;143:109245. Epub 2023 May 12 doi: 10.1016/j.yebeh.2023.109245. PMID: 37182500
Management of refractory status epilepticus in adults: still more questions than answers.
Rossetti AO, Lowenstein DH
Lancet Neurol 2011 Oct;10(10):922-30. doi: 10.1016/S1474-4422(11)70187-9. PMID: 21939901Free PMC Article

Recent clinical studies

Etiology

Elderly patients with nonconvulsive status epilepticus: Clinical-EEG data, hospital mortality, STESS and EMSE.
Tedrus GM, Nogueira E Junior, Vidal MA
Seizure 2022 Jan;94:18-22. Epub 2021 Nov 11 doi: 10.1016/j.seizure.2021.11.004. PMID: 34808547
Status epilepticus without impairment of consciousness: Long-term outcomes according to duration.
Santamarina E, Parejo-Carbonell B, Abraira L, Gutiérrez-Viedma A, Fonseca E, Seijo I, Abarrategui B, Salas-Puig X, Quintana M, Toledo M, García-Morales I
Epilepsy Behav 2021 Jul;120:108007. Epub 2021 May 13 doi: 10.1016/j.yebeh.2021.108007. PMID: 33992961
Nonconvulsive status epilepticus in the elderly.
Dupont S, Kinugawa K
Rev Neurol (Paris) 2020 Nov;176(9):701-709. Epub 2020 Mar 10 doi: 10.1016/j.neurol.2019.12.007. PMID: 32169326
Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review.
Manfredonia F, Saturno E, Lawley A, Gasverde S, Cavanna AE
J Neurol Sci 2020 Mar 15;410:116674. Epub 2020 Jan 7 doi: 10.1016/j.jns.2020.116674. PMID: 31931342
Prognosis of status epilepticus in elderly patients.
Vilella L, González Cuevas M, Quintana Luque M, Toledo M, Sueiras Gil M, Guzmán L, Salas Puig J, Santamarina Pérez E
Acta Neurol Scand 2018 Mar;137(3):321-328. Epub 2017 Nov 22 doi: 10.1111/ane.12867. PMID: 29168175

Diagnosis

Focal nonconvulsive status epilepticus with impaired consciousness in older adults: Prognosis-related variables.
Tedrus GMAS
Epilepsy Behav 2023 Jul;144:109257. Epub 2023 Jun 2 doi: 10.1016/j.yebeh.2023.109257. PMID: 37271017
Nonconvulsive status epilepticus in the elderly.
Dupont S, Kinugawa K
Rev Neurol (Paris) 2020 Nov;176(9):701-709. Epub 2020 Mar 10 doi: 10.1016/j.neurol.2019.12.007. PMID: 32169326
Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review.
Manfredonia F, Saturno E, Lawley A, Gasverde S, Cavanna AE
J Neurol Sci 2020 Mar 15;410:116674. Epub 2020 Jan 7 doi: 10.1016/j.jns.2020.116674. PMID: 31931342
Management of refractory status epilepticus in adults: still more questions than answers.
Rossetti AO, Lowenstein DH
Lancet Neurol 2011 Oct;10(10):922-30. doi: 10.1016/S1474-4422(11)70187-9. PMID: 21939901Free PMC Article
Nonconvulsive status epilepticus and coma.
Bauer G, Trinka E
Epilepsia 2010 Feb;51(2):177-90. Epub 2009 Sep 10 doi: 10.1111/j.1528-1167.2009.02297.x. PMID: 19744116

Therapy

Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.
Caraballo RH, Reyes Valenzuela G, Fortini S, Espeche A, Gamboni B, Silva W, Semprino M, Fasulo L, Chacón S, Gallo A, Galicchio S, Cachia P
Epilepsy Behav 2023 Jun;143:109245. Epub 2023 May 12 doi: 10.1016/j.yebeh.2023.109245. PMID: 37182500
Refractory Status Epilepticus: Risk Factors and Analysis of Intubation in the Multicenter SENSE Registry.
Beuchat I, Rosenow F, Kellinghaus C, Trinka E, Unterberger I, Rüegg S, Sutter R, Tilz C, Uzelac Z, Rossetti AO, Strzelczyk A
Neurology 2022 Oct 18;99(16):e1824-e1834. Epub 2022 Aug 10 doi: 10.1212/WNL.0000000000201099. PMID: 35948449
Nonconvulsive status epilepticus in the elderly.
Dupont S, Kinugawa K
Rev Neurol (Paris) 2020 Nov;176(9):701-709. Epub 2020 Mar 10 doi: 10.1016/j.neurol.2019.12.007. PMID: 32169326
Prognosis of status epilepticus in elderly patients.
Vilella L, González Cuevas M, Quintana Luque M, Toledo M, Sueiras Gil M, Guzmán L, Salas Puig J, Santamarina Pérez E
Acta Neurol Scand 2018 Mar;137(3):321-328. Epub 2017 Nov 22 doi: 10.1111/ane.12867. PMID: 29168175
Management of refractory status epilepticus in adults: still more questions than answers.
Rossetti AO, Lowenstein DH
Lancet Neurol 2011 Oct;10(10):922-30. doi: 10.1016/S1474-4422(11)70187-9. PMID: 21939901Free PMC Article

Prognosis

Focal nonconvulsive status epilepticus with impaired consciousness in older adults: Prognosis-related variables.
Tedrus GMAS
Epilepsy Behav 2023 Jul;144:109257. Epub 2023 Jun 2 doi: 10.1016/j.yebeh.2023.109257. PMID: 37271017
Status epilepticus without impairment of consciousness: Long-term outcomes according to duration.
Santamarina E, Parejo-Carbonell B, Abraira L, Gutiérrez-Viedma A, Fonseca E, Seijo I, Abarrategui B, Salas-Puig X, Quintana M, Toledo M, García-Morales I
Epilepsy Behav 2021 Jul;120:108007. Epub 2021 May 13 doi: 10.1016/j.yebeh.2021.108007. PMID: 33992961
Nonconvulsive status epilepticus in the elderly.
Dupont S, Kinugawa K
Rev Neurol (Paris) 2020 Nov;176(9):701-709. Epub 2020 Mar 10 doi: 10.1016/j.neurol.2019.12.007. PMID: 32169326
Prognosis of status epilepticus in elderly patients.
Vilella L, González Cuevas M, Quintana Luque M, Toledo M, Sueiras Gil M, Guzmán L, Salas Puig J, Santamarina Pérez E
Acta Neurol Scand 2018 Mar;137(3):321-328. Epub 2017 Nov 22 doi: 10.1111/ane.12867. PMID: 29168175
Status epilepticus.
Treiman DM
Baillieres Clin Neurol 1996 Dec;5(4):821-39. PMID: 9068883

Clinical prediction guides

Focal nonconvulsive status epilepticus with impaired consciousness in older adults: Prognosis-related variables.
Tedrus GMAS
Epilepsy Behav 2023 Jul;144:109257. Epub 2023 Jun 2 doi: 10.1016/j.yebeh.2023.109257. PMID: 37271017
Elderly patients with nonconvulsive status epilepticus: Clinical-EEG data, hospital mortality, STESS and EMSE.
Tedrus GM, Nogueira E Junior, Vidal MA
Seizure 2022 Jan;94:18-22. Epub 2021 Nov 11 doi: 10.1016/j.seizure.2021.11.004. PMID: 34808547
Prognosis of status epilepticus in elderly patients.
Vilella L, González Cuevas M, Quintana Luque M, Toledo M, Sueiras Gil M, Guzmán L, Salas Puig J, Santamarina Pérez E
Acta Neurol Scand 2018 Mar;137(3):321-328. Epub 2017 Nov 22 doi: 10.1111/ane.12867. PMID: 29168175
Management of refractory status epilepticus in adults: still more questions than answers.
Rossetti AO, Lowenstein DH
Lancet Neurol 2011 Oct;10(10):922-30. doi: 10.1016/S1474-4422(11)70187-9. PMID: 21939901Free PMC Article
Status epilepticus.
Treiman DM
Baillieres Clin Neurol 1996 Dec;5(4):821-39. PMID: 9068883

Recent systematic reviews

Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review.
Manfredonia F, Saturno E, Lawley A, Gasverde S, Cavanna AE
J Neurol Sci 2020 Mar 15;410:116674. Epub 2020 Jan 7 doi: 10.1016/j.jns.2020.116674. PMID: 31931342
Incidence of seizure in stroke patients treated with recombinant tissue plasminogen activator: A systematic review and meta-analysis.
Lekoubou A, Awoumou JJ, Kengne AP
Int J Stroke 2017 Dec;12(9):923-931. Epub 2017 Sep 5 doi: 10.1177/1747493017729239. PMID: 28872451

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