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Sinonasal Human Papillomavirus-Related Carcinoma with Adenoid Cystic-Like Features

MedGen UID:
1739108
•Concept ID:
C5420023
•
Neoplastic Process
Synonyms: Sinonasal HPV-Related Carcinoma with Adenoid Cystic-Like Features; Sinonasal Tract HPV-Related Carcinoma with Adenoid Cystic-Like Features; Sinonasal Tract Human Papillomavirus-Related Carcinoma with Adenoid Cystic-Like Features

Definition

A distinctive HPV-related non-keratinizing squamous cell carcinoma of the sinonasal tract arising most frequently from the maxillary sinus or nasal cavity. Most patients present with nasal obstruction and/or epistaxis. It is characterized by the presence of basaloid cell proliferations separated by collagenous fibrous bands. The basaloid cells align around microcystic spaces. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Human Papillomavirus-Related Carcinoma with Adenoid Cystic-Like Features

Recent clinical studies

Etiology

Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma: A Recent Discovery. A Case Report and Literature Review.
Brzezinska K, Hammad A
Head Neck Pathol 2020 Jun;14(2):473-479. Epub 2019 Aug 31 doi: 10.1007/s12105-019-01069-3. PMID: 31473938Free PMC Article
Human Papillomavirus-Related Carcinoma With Adenoid Cystic-like Features of the Sinonasal Tract (Also Known as Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma).
Chen CC, Yang SF
Arch Pathol Lab Med 2019 Nov;143(11):1420-1424. Epub 2019 Mar 6 doi: 10.5858/arpa.2018-0027-RS. PMID: 30838880
Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma with Unique HPV type 52 Association: A Case Report with Review of Literature.
Adamane SA, Mittal N, Teni T, Pawar S, Waghole R, Bal M
Head Neck Pathol 2019 Sep;13(3):331-338. Epub 2018 Sep 26 doi: 10.1007/s12105-018-0969-4. PMID: 30259271Free PMC Article
Human papillomavirus-related carcinoma with adenoid cystic-like features: a series of five cases expanding the pathological spectrum.
Hang JF, Hsieh MS, Li WY, Chen JY, Lin SY, Liu SH, Pan CC, Kuo YJ
Histopathology 2017 Dec;71(6):887-896. Epub 2017 Sep 15 doi: 10.1111/his.13301. PMID: 28664668
Human papillomavirus-related carcinoma with adenoid cystic-like features: a peculiar variant of head and neck cancer restricted to the sinonasal tract.
Bishop JA, Ogawa T, Stelow EB, Moskaluk CA, Koch WM, Pai SI, Westra WH
Am J Surg Pathol 2013 Jun;37(6):836-44. doi: 10.1097/PAS.0b013e31827b1cd6. PMID: 23598962Free PMC Article

Diagnosis

Human Papillomavirus-Related Carcinoma With Adenoid Cystic-like Features of the Sinonasal Tract (Also Known as Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma).
Chen CC, Yang SF
Arch Pathol Lab Med 2019 Nov;143(11):1420-1424. Epub 2019 Mar 6 doi: 10.5858/arpa.2018-0027-RS. PMID: 30838880
Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma with Unique HPV type 52 Association: A Case Report with Review of Literature.
Adamane SA, Mittal N, Teni T, Pawar S, Waghole R, Bal M
Head Neck Pathol 2019 Sep;13(3):331-338. Epub 2018 Sep 26 doi: 10.1007/s12105-018-0969-4. PMID: 30259271Free PMC Article
Consistent LEF-1 and MYB Immunohistochemical Expression in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma: A Potential Diagnostic Pitfall.
Shah AA, Oliai BR, Bishop JA
Head Neck Pathol 2019 Jun;13(2):220-224. Epub 2018 Jul 19 doi: 10.1007/s12105-018-0951-1. PMID: 30027386Free PMC Article
Human papillomavirus-related carcinoma with adenoid cystic-like features: a series of five cases expanding the pathological spectrum.
Hang JF, Hsieh MS, Li WY, Chen JY, Lin SY, Liu SH, Pan CC, Kuo YJ
Histopathology 2017 Dec;71(6):887-896. Epub 2017 Sep 15 doi: 10.1111/his.13301. PMID: 28664668

Prognosis

Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma: A Recent Discovery. A Case Report and Literature Review.
Brzezinska K, Hammad A
Head Neck Pathol 2020 Jun;14(2):473-479. Epub 2019 Aug 31 doi: 10.1007/s12105-019-01069-3. PMID: 31473938Free PMC Article
Human Papillomavirus-Related Carcinoma With Adenoid Cystic-like Features of the Sinonasal Tract (Also Known as Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma).
Chen CC, Yang SF
Arch Pathol Lab Med 2019 Nov;143(11):1420-1424. Epub 2019 Mar 6 doi: 10.5858/arpa.2018-0027-RS. PMID: 30838880
Human papillomavirus-related carcinoma with adenoid cystic-like features of the sinonasal tract: clinical and morphological characterization of six new cases.
Andreasen S, Bishop JA, Hansen TV, Westra WH, Bilde A, von Buchwald C, Kiss K
Histopathology 2017 May;70(6):880-888. Epub 2017 Feb 24 doi: 10.1111/his.13162. PMID: 28035703

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