U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Adams-Stokes syndrome

MedGen UID:
1741
•Concept ID:
C0001396
•
Disease or Syndrome
Synonyms: Adam Stokes Attacks; Adam-Stokes Attacks; Adams Stokes Syndrome; Adams-Stokes Syndrome; Attacks, Adam-Stokes; Attacks, Stokes-Adams; Stokes Adams Attacks; Stokes Adams Syndrome; Stokes-Adams Attacks; Stokes-Adams Syndrome; Syndrome, Adams-Stokes; Syndrome, Stokes-Adams
SNOMED CT: Stokes-Adams attack (271547004)
 
Monarch Initiative: MONDO:0043475

Definition

An episode of sudden and transient loss of consciousness sometimes associated with seizures. It is caused by a sudden decrease of the cardiac output that results from a sudden cardiac dysrhythmia. Typically patients develop an initial pallor, followed by facial flush during recovery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdams-Stokes syndrome

Professional guidelines

PubMed

Management of Stokes-Adams syndrome.
Sigurd B, Sandøe E
Cardiology 1990;77(3):195-208. doi: 10.1159/000174601. PMID: 2272057
Intracardiac pacing as emergency treatment in Adams-Stokes syndrome.
Bay G, Sivertssen E
Br Med J 1967 Oct 28;4(5573):199-200. doi: 10.1136/bmj.4.5573.199. PMID: 6053987Free PMC Article
MANAGEMENT OF THE STOKES-ADAMS SYNDROME.
DACK S
Am Heart J 1963 Nov;66:579-83. doi: 10.1016/0002-8703(63)90312-0. PMID: 14083777

Recent clinical studies

Etiology

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
Cardiac pacemaker treatment of heart block in Enugu a 5-year review.
Ekpe EE, Aghaji MA, Edaigbini SA, Onwuta CN
Niger J Med 2008 Jan-Mar;17(1):7-12. doi: 10.4314/njm.v17i1.37346. PMID: 18390124
Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
A-V block.
Hori K, Kawai C
Jpn Circ J 1976 Mar;40(3):217-23. doi: 10.1253/jcj.40.217. PMID: 1271574

Diagnosis

Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
Management of Stokes-Adams syndrome.
Sigurd B, Sandøe E
Cardiology 1990;77(3):195-208. doi: 10.1159/000174601. PMID: 2272057
The Stokes-Adams syndrome.
O'Rourke RA
Med Ann Dist Columbia 1972 Jun;41(6):369-71. PMID: 4504015
The Stokes-Adams syndrome.
Scherf D, Bornemann C
Cardiovasc Clin 1970;2(2):101-16. PMID: 4149973
The Stokes-Adams syndrome.
Pomerantz B, O'Rourke RA
Am J Med 1969 Jun;46(6):941-60. doi: 10.1016/0002-9343(69)90096-5. PMID: 4978920

Therapy

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
A complicated chinese herbal medicine nephrotoxicity.
Omer Mohamed HA, Osman OM, Ali HH, Asiri MN, Hassan AA, Almangah IM, Elkarib AO, AbBshabshe A
Saudi J Kidney Dis Transpl 2020 Mar-Apr;31(2):533-536. doi: 10.4103/1319-2442.284032. PMID: 32394930
The Stokes-Adams syndrome.
Scherf D, Bornemann C
Cardiovasc Clin 1970;2(2):101-16. PMID: 4149973
The Stokes-Adams syndrome.
Pomerantz B, O'Rourke RA
Am J Med 1969 Jun;46(6):941-60. doi: 10.1016/0002-9343(69)90096-5. PMID: 4978920
Adams-Stokes attacks and corticosteroids.
Roberts CI, Wharton CF
Br Med J 1968 Mar 30;1(5595):841. doi: 10.1136/bmj.1.5595.841. PMID: 5641502Free PMC Article

Prognosis

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Paroxysmal Ventricular Standstill: A Rare Cardiac Manifestation of Syncope.
Adegoke DA
Am J Case Rep 2020 Jun 17;21:e924381. doi: 10.12659/AJCR.924381. PMID: 32598337Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
Surdocardiac and related syndromes in children.
Jervell A
Adv Intern Med 1971;17:425-38. PMID: 4267292

Clinical prediction guides

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Paroxysmal Ventricular Standstill: A Rare Cardiac Manifestation of Syncope.
Adegoke DA
Am J Case Rep 2020 Jun 17;21:e924381. doi: 10.12659/AJCR.924381. PMID: 32598337Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
William Osler: slow pulse, stokes-adams disease, and sudden death in families.
Wooley CF, Bliss M
Am Heart Hosp J 2006 Winter;4(1):60-5. doi: 10.1111/j.1541-9215.2006.05237.x. PMID: 16470107
Arrhythmias in primary pulmonary hypertension.
Kanemoto N, Sasamoto H
Jpn Heart J 1979 Nov;20(6):765-75. doi: 10.1536/ihj.20.765. PMID: 522240

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...