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Adams-Stokes syndrome

MedGen UID:
1741
•Concept ID:
C0001396
•
Disease or Syndrome
Synonyms: Adam Stokes Attacks; Adam-Stokes Attacks; Adams Stokes Syndrome; Adams-Stokes Syndrome; Attacks, Adam-Stokes; Attacks, Stokes-Adams; Stokes Adams Attacks; Stokes Adams Syndrome; Stokes-Adams Attacks; Stokes-Adams Syndrome; Syndrome, Adams-Stokes; Syndrome, Stokes-Adams
SNOMED CT: Stokes-Adams attack (271547004)
 
Monarch Initiative: MONDO:0043475

Definition

An episode of sudden and transient loss of consciousness sometimes associated with seizures. It is caused by a sudden decrease of the cardiac output that results from a sudden cardiac dysrhythmia. Typically patients develop an initial pallor, followed by facial flush during recovery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdams-Stokes syndrome

Professional guidelines

PubMed

Management of Stokes-Adams syndrome.
Sigurd B, Sandøe E
Cardiology 1990;77(3):195-208. doi: 10.1159/000174601. PMID: 2272057
The Stokes-Adams syndrome: mechanisms and treatment.
O'Rourke RA
Mich Med 1972 Apr;71(11):323-4. PMID: 5014675
MANAGEMENT OF THE STOKES-ADAMS SYNDROME.
DACK S
Am Heart J 1963 Nov;66:579-83. doi: 10.1016/0002-8703(63)90312-0. PMID: 14083777

Recent clinical studies

Etiology

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
Cardiac pacemaker treatment of heart block in Enugu a 5-year review.
Ekpe EE, Aghaji MA, Edaigbini SA, Onwuta CN
Niger J Med 2008 Jan-Mar;17(1):7-12. doi: 10.4314/njm.v17i1.37346. PMID: 18390124
Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
A-V block.
Hori K, Kawai C
Jpn Circ J 1976 Mar;40(3):217-23. doi: 10.1253/jcj.40.217. PMID: 1271574

Diagnosis

Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
Management of Stokes-Adams syndrome.
Sigurd B, Sandøe E
Cardiology 1990;77(3):195-208. doi: 10.1159/000174601. PMID: 2272057
Bradycardia.
Dighton DH
Practitioner 1980 Mar;224(1341):261-6. PMID: 7403005
The Stokes-Adams syndrome.
Scherf D, Bornemann C
Cardiovasc Clin 1970;2(2):101-16. PMID: 4149973
The Stokes-Adams syndrome.
Pomerantz B, O'Rourke RA
Am J Med 1969 Jun;46(6):941-60. doi: 10.1016/0002-9343(69)90096-5. PMID: 4978920

Therapy

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
Bradycardia.
Dighton DH
Practitioner 1980 Mar;224(1341):261-6. PMID: 7403005
The Stokes-Adams syndrome.
Scherf D, Bornemann C
Cardiovasc Clin 1970;2(2):101-16. PMID: 4149973
The Stokes-Adams syndrome.
Pomerantz B, O'Rourke RA
Am J Med 1969 Jun;46(6):941-60. doi: 10.1016/0002-9343(69)90096-5. PMID: 4978920

Prognosis

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Paroxysmal Ventricular Standstill: A Rare Cardiac Manifestation of Syncope.
Adegoke DA
Am J Case Rep 2020 Jun 17;21:e924381. doi: 10.12659/AJCR.924381. PMID: 32598337Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
Hemiblocks revisited.
Elizari MV, Acunzo RS, Ferreiro M
Circulation 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389. PMID: 17339573
Adams-Stokes syndrome. A review and follow-up study of forty-two cases.
JOHANSSON BW
Am J Cardiol 1961 Jul;8:76-93. doi: 10.1016/0002-9149(61)90181-3. PMID: 13790191

Clinical prediction guides

Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Paroxysmal Ventricular Standstill: A Rare Cardiac Manifestation of Syncope.
Adegoke DA
Am J Case Rep 2020 Jun 17;21:e924381. doi: 10.12659/AJCR.924381. PMID: 32598337Free PMC Article
Emergency Physician Attitudes, Preferences, and Risk Tolerance for Stroke as a Potential Cause of Dizziness Symptoms.
Kene MV, Ballard DW, Vinson DR, Rauchwerger AS, Iskin HR, Kim AS
West J Emerg Med 2015 Sep;16(5):768-76. Epub 2015 Oct 20 doi: 10.5811/westjem.2015.7.26158. PMID: 26587108Free PMC Article
Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature.
Carano N, Bo I, Tchana B, Vecchione E, Fantoni S, Agnetti A
Ital J Pediatr 2012 Oct 30;38:61. doi: 10.1186/1824-7288-38-61. PMID: 23110777Free PMC Article
William Osler: slow pulse, stokes-adams disease, and sudden death in families.
Wooley CF, Bliss M
Am Heart Hosp J 2006 Winter;4(1):60-5. doi: 10.1111/j.1541-9215.2006.05237.x. PMID: 16470107

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