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CCND1 Gene Rearrangement

MedGen UID:
1744424
•Concept ID:
C5401390
•
Cell or Molecular Dysfunction
Synonyms: BCL-1 Gene Rearrangement; BCL1 Gene Rearrangement; CCND1 Rearrangement; Cyclin D1 Gene Rearrangement; PRAD1 Gene Rearrangement

Definition

A molecular abnormality indicating rearrangement of the CCND1 gene. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCCND1 Gene Rearrangement

Professional guidelines

PubMed

Clinical Utility of Cerebrospinal Fluid Cell-Free DNA as Liquid Biopsy for Leptomeningeal Metastases in ALK-Rearranged NSCLC.
Zheng MM, Li YS, Jiang BY, Tu HY, Tang WF, Yang JJ, Zhang XC, Ye JY, Yan HH, Su J, Zhou Q, Zhong WZ, Yang XN, Guo WB, Chuai S, Zhang Z, Chen HJ, Wang Z, Liu C, Wu YL
J Thorac Oncol 2019 May;14(5):924-932. Epub 2019 Jan 17 doi: 10.1016/j.jtho.2019.01.007. PMID: 30659989
Mantle cell lymphoma: diagnostic criteria, clinical aspects and therapeutic problems.
Meusers P, Hense J, Brittinger G
Leukemia 1997 Apr;11 Suppl 2:S60-4. PMID: 9178843

Recent clinical studies

Etiology

Cutaneous Involvement in Plasma Cell Myeloma.
Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML
Am J Clin Pathol 2021 Jan 4;155(1):106-116. doi: 10.1093/ajcp/aqaa122. PMID: 32885235
Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Diagnosis

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Therapy

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Prognosis

Histiocytic Sarcoma With CCND1 Gene Rearrangement Clonally Related and Transdifferentiated From Mantle Cell Lymphoma.
Kumar J, Al-Kawaaz M, Martin BA, Hegazi MM, Tan B, Gratzinger D
Am J Clin Pathol 2022 Oct 6;158(4):449-455. doi: 10.1093/ajcp/aqac087. PMID: 35964234
Cutaneous Involvement in Plasma Cell Myeloma.
Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML
Am J Clin Pathol 2021 Jan 4;155(1):106-116. doi: 10.1093/ajcp/aqaa122. PMID: 32885235

Clinical prediction guides

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

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