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Refractory Grade 3a Follicular Lymphoma

MedGen UID:
1749172
Concept ID:
C5419584
Neoplastic Process

Definition

Grade 3a follicular lymphoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Grade 3a Follicular Lymphoma

Professional guidelines

PubMed

Ghione P, Palomba ML, Ghesquieres H, Bobillo S, Patel AR, Nahas M, Kanters S, Deighton K, Hatswell A, Ma L, Limbrick-Oldfield EH, Snider JT, Wade SW, Riberio MT, Radford J, Beygi S, Gribben J
Haematologica 2023 Mar 1;108(3):822-832. doi: 10.3324/haematol.2022.281421. PMID: 36263843Free PMC Article
Bouchkouj N, Lin X, Wang X, Przepiorka D, Xu Z, Purohit-Sheth T, Theoret M
Oncologist 2022 Oct 1;27(10):892-899. doi: 10.1093/oncolo/oyac163. PMID: 35983953Free PMC Article
Casulo C, Larson MC, Lunde JJ, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan J, Flowers CR, Link BK, Maurer MJ
Lancet Haematol 2022 Apr;9(4):e289-e300. doi: 10.1016/S2352-3026(22)00033-3. PMID: 35358443Free PMC Article

Recent clinical studies

Etiology

Linton KM, Vitolo U, Jurczak W, Lugtenburg PJ, Gyan E, Sureda A, Christensen JH, Hess B, Tilly H, Cordoba R, Lewis DJ, Okada C, Hutchings M, Clausen MR, Sancho JM, Cochrane T, Leppä S, Chamuleau MED, Gernhardt D, Altıntaş I, Liu Y, Ahmadi T, Dinh MH, Hoehn D, Favaro E, Elliott B, Thieblemont C, Vose JM
Lancet Haematol 2024 Aug;11(8):e593-e605. Epub 2024 Jun 15 doi: 10.1016/S2352-3026(24)00166-2. PMID: 38889737
Ghione P, Palomba ML, Ghesquieres H, Bobillo S, Patel AR, Nahas M, Kanters S, Deighton K, Hatswell A, Ma L, Limbrick-Oldfield EH, Snider JT, Wade SW, Riberio MT, Radford J, Beygi S, Gribben J
Haematologica 2023 Mar 1;108(3):822-832. doi: 10.3324/haematol.2022.281421. PMID: 36263843Free PMC Article
Budde LE, Sehn LH, Matasar M, Schuster SJ, Assouline S, Giri P, Kuruvilla J, Canales M, Dietrich S, Fay K, Ku M, Nastoupil L, Cheah CY, Wei MC, Yin S, Li CC, Huang H, Kwan A, Penuel E, Bartlett NL
Lancet Oncol 2022 Aug;23(8):1055-1065. Epub 2022 Jul 5 doi: 10.1016/S1470-2045(22)00335-7. PMID: 35803286
Morschhauser F, Tilly H, Chaidos A, McKay P, Phillips T, Assouline S, Batlevi CL, Campbell P, Ribrag V, Damaj GL, Dickinson M, Jurczak W, Kazmierczak M, Opat S, Radford J, Schmitt A, Yang J, Whalen J, Agarwal S, Adib D, Salles G
Lancet Oncol 2020 Nov;21(11):1433-1442. Epub 2020 Oct 6 doi: 10.1016/S1470-2045(20)30441-1. PMID: 33035457Free PMC Article
Morschhauser F, Le Gouill S, Feugier P, Bailly S, Nicolas-Virelizier E, Bijou F, Salles GA, Tilly H, Fruchart C, Van Eygen K, Snauwaert S, Bonnet C, Haioun C, Thieblemont C, Bouabdallah R, Wu KL, Canioni D, Meignin V, Cartron G, Houot R
Lancet Haematol 2019 Aug;6(8):e429-e437. Epub 2019 Jul 8 doi: 10.1016/S2352-3026(19)30089-4. PMID: 31296423

Diagnosis

Mozas P, López C, Grau M, Nadeu F, Clot G, Valle S, Kulis M, Navarro A, Ramis-Zaldivar JE, González-Farré B, Rivas-Delgado A, Rivero A, Frigola G, Balagué O, Giné E, Delgado J, Villamor N, Matutes E, Magnano L, García-Sanz R, Huet S, Russell RB, Campo E, López-Guillermo A, Beà S
Hematol Oncol 2023 Oct;41(4):631-643. Epub 2023 Mar 30 doi: 10.1002/hon.3132. PMID: 36994552
Ghione P, Palomba ML, Ghesquieres H, Bobillo S, Patel AR, Nahas M, Kanters S, Deighton K, Hatswell A, Ma L, Limbrick-Oldfield EH, Snider JT, Wade SW, Riberio MT, Radford J, Beygi S, Gribben J
Haematologica 2023 Mar 1;108(3):822-832. doi: 10.3324/haematol.2022.281421. PMID: 36263843Free PMC Article
Muntañola A, Mozas P, Mercadal S, Huguet M, Bobillo S, Bastos-Oreiro M, Jiménez-Ubieto A, Rovira J, Rivero A, Tolosa C, Luizaga L, de Villambrosia SG, Novelli S, Caballero D, Salar A, Alonso-Álvarez S, Magnano L, Gutiérrez NC, Sancho JM, López-Guillermo A; GELTAMO group (Grupo Español de Linfomas y Trasplante de Médula Ósea)
Br J Haematol 2023 Feb;200(3):306-314. Epub 2022 Oct 19 doi: 10.1111/bjh.18522. PMID: 36261137
Casulo C, Larson MC, Lunde JJ, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan J, Flowers CR, Link BK, Maurer MJ
Lancet Haematol 2022 Apr;9(4):e289-e300. doi: 10.1016/S2352-3026(22)00033-3. PMID: 35358443Free PMC Article
Alonso-Álvarez S, Manni M, Montoto S, Sarkozy C, Morschhauser F, Wondergem MJ, Guarini A, Magnano L, Alcoceba M, Chamuleau M, Galimberti S, Gomes da Silva M, Holte H, Zucca E, Lockmer S, Aurer I, Marcheselli L, Stepanishyna Y, Caballero Barrigón MD, Salles G, Federico M
Eur J Cancer 2021 Nov;157:132-139. Epub 2021 Sep 8 doi: 10.1016/j.ejca.2021.08.005. PMID: 34508995

Therapy

Linton KM, Vitolo U, Jurczak W, Lugtenburg PJ, Gyan E, Sureda A, Christensen JH, Hess B, Tilly H, Cordoba R, Lewis DJ, Okada C, Hutchings M, Clausen MR, Sancho JM, Cochrane T, Leppä S, Chamuleau MED, Gernhardt D, Altıntaş I, Liu Y, Ahmadi T, Dinh MH, Hoehn D, Favaro E, Elliott B, Thieblemont C, Vose JM
Lancet Haematol 2024 Aug;11(8):e593-e605. Epub 2024 Jun 15 doi: 10.1016/S2352-3026(24)00166-2. PMID: 38889737
Ghione P, Palomba ML, Ghesquieres H, Bobillo S, Patel AR, Nahas M, Kanters S, Deighton K, Hatswell A, Ma L, Limbrick-Oldfield EH, Snider JT, Wade SW, Riberio MT, Radford J, Beygi S, Gribben J
Haematologica 2023 Mar 1;108(3):822-832. doi: 10.3324/haematol.2022.281421. PMID: 36263843Free PMC Article
Budde LE, Sehn LH, Matasar M, Schuster SJ, Assouline S, Giri P, Kuruvilla J, Canales M, Dietrich S, Fay K, Ku M, Nastoupil L, Cheah CY, Wei MC, Yin S, Li CC, Huang H, Kwan A, Penuel E, Bartlett NL
Lancet Oncol 2022 Aug;23(8):1055-1065. Epub 2022 Jul 5 doi: 10.1016/S1470-2045(22)00335-7. PMID: 35803286
Morschhauser F, Tilly H, Chaidos A, McKay P, Phillips T, Assouline S, Batlevi CL, Campbell P, Ribrag V, Damaj GL, Dickinson M, Jurczak W, Kazmierczak M, Opat S, Radford J, Schmitt A, Yang J, Whalen J, Agarwal S, Adib D, Salles G
Lancet Oncol 2020 Nov;21(11):1433-1442. Epub 2020 Oct 6 doi: 10.1016/S1470-2045(20)30441-1. PMID: 33035457Free PMC Article
Morschhauser F, Le Gouill S, Feugier P, Bailly S, Nicolas-Virelizier E, Bijou F, Salles GA, Tilly H, Fruchart C, Van Eygen K, Snauwaert S, Bonnet C, Haioun C, Thieblemont C, Bouabdallah R, Wu KL, Canioni D, Meignin V, Cartron G, Houot R
Lancet Haematol 2019 Aug;6(8):e429-e437. Epub 2019 Jul 8 doi: 10.1016/S2352-3026(19)30089-4. PMID: 31296423

Prognosis

Dreyling M, Fowler NH, Dickinson M, Martinez-Lopez J, Kolstad A, Butler J, Ghosh M, Popplewell L, Chavez JC, Bachy E, Kato K, Harigae H, Kersten MJ, Andreadis C, Riedell PA, Ho PJ, Pérez-Simón JA, Chen AI, Nastoupil LJ, von Tresckow B, María Ferreri AJ, Teshima T, Patten PEM, McGuirk JP, Petzer AL, Offner F, Viardot A, Zinzani PL, Malladi R, Paule I, Zia A, Awasthi R, Han X, Germano D, O'Donovan D, Ramos R, Maier HJ, Masood A, Thieblemont C, Schuster SJ
Blood 2024 Apr 25;143(17):1713-1725. doi: 10.1182/blood.2023021567. PMID: 38194692Free PMC Article
Mozas P, López C, Grau M, Nadeu F, Clot G, Valle S, Kulis M, Navarro A, Ramis-Zaldivar JE, González-Farré B, Rivas-Delgado A, Rivero A, Frigola G, Balagué O, Giné E, Delgado J, Villamor N, Matutes E, Magnano L, García-Sanz R, Huet S, Russell RB, Campo E, López-Guillermo A, Beà S
Hematol Oncol 2023 Oct;41(4):631-643. Epub 2023 Mar 30 doi: 10.1002/hon.3132. PMID: 36994552
Alonso-Álvarez S, Manni M, Montoto S, Sarkozy C, Morschhauser F, Wondergem MJ, Guarini A, Magnano L, Alcoceba M, Chamuleau M, Galimberti S, Gomes da Silva M, Holte H, Zucca E, Lockmer S, Aurer I, Marcheselli L, Stepanishyna Y, Caballero Barrigón MD, Salles G, Federico M
Eur J Cancer 2021 Nov;157:132-139. Epub 2021 Sep 8 doi: 10.1016/j.ejca.2021.08.005. PMID: 34508995
Morschhauser F, Le Gouill S, Feugier P, Bailly S, Nicolas-Virelizier E, Bijou F, Salles GA, Tilly H, Fruchart C, Van Eygen K, Snauwaert S, Bonnet C, Haioun C, Thieblemont C, Bouabdallah R, Wu KL, Canioni D, Meignin V, Cartron G, Houot R
Lancet Haematol 2019 Aug;6(8):e429-e437. Epub 2019 Jul 8 doi: 10.1016/S2352-3026(19)30089-4. PMID: 31296423
Miao Y, Hu S, Lu X, Li S, Wang W, Medeiros LJ, Lin P
Hum Pathol 2016 Dec;58:72-77. Epub 2016 Aug 18 doi: 10.1016/j.humpath.2016.07.025. PMID: 27544800

Clinical prediction guides

Merryman RW, Redd RA, Freedman AS, Ahn IE, Brown JR, Crombie JL, Davids MS, Fisher DC, Jacobsen ED, Kim AI, LaCasce AS, Ng S, Odejide OO, Parry EM, Isufi I, Kline J, Cohen JB, Mehta-Shah N, Bartlett NL, Mei M, Kuntz TM, Wolff J, Rodig SJ, Armand P, Jacobson CA
Ann Hematol 2024 Jan;103(1):185-198. Epub 2023 Oct 18 doi: 10.1007/s00277-023-05475-0. PMID: 37851072
Budde LE, Sehn LH, Matasar M, Schuster SJ, Assouline S, Giri P, Kuruvilla J, Canales M, Dietrich S, Fay K, Ku M, Nastoupil L, Cheah CY, Wei MC, Yin S, Li CC, Huang H, Kwan A, Penuel E, Bartlett NL
Lancet Oncol 2022 Aug;23(8):1055-1065. Epub 2022 Jul 5 doi: 10.1016/S1470-2045(22)00335-7. PMID: 35803286
Bannerji R, Arnason JE, Advani RH, Brown JR, Allan JN, Ansell SM, Barnes JA, O'Brien SM, Chávez JC, Duell J, Rosenwald A, Crombie JL, Ufkin M, Li J, Zhu M, Ambati SR, Chaudhry A, Lowy I, Topp MS
Lancet Haematol 2022 May;9(5):e327-e339. Epub 2022 Apr 1 doi: 10.1016/S2352-3026(22)00072-2. PMID: 35366963Free PMC Article
Casulo C, Larson MC, Lunde JJ, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan J, Flowers CR, Link BK, Maurer MJ
Lancet Haematol 2022 Apr;9(4):e289-e300. doi: 10.1016/S2352-3026(22)00033-3. PMID: 35358443Free PMC Article
Miao Y, Hu S, Lu X, Li S, Wang W, Medeiros LJ, Lin P
Hum Pathol 2016 Dec;58:72-77. Epub 2016 Aug 18 doi: 10.1016/j.humpath.2016.07.025. PMID: 27544800

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