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Malignant lymphoma, centroblastic type, follicular

MedGen UID:
36334
•Concept ID:
C0079745
•
Neoplastic Process
Synonyms: Follicular Large Cell Lymphoma; Follicular Large-Cell Lymphoma; Follicular Large-Cell Lymphomas; Histiocytic Lymphoma, Nodular; Histiocytic Lymphomas, Nodular; Large Cell Lymphoma, Follicular; Large Lymphoid Lymphoma, Nodular; Large-Cell Lymphoma, Follicular; Large-Cell Lymphomas, Follicular; Lymphoma, Follicular Large Cell; Lymphoma, Follicular Large-Cell; Lymphoma, Histiocytic, Nodular; Lymphoma, Large Cell, Follicular; Lymphoma, Large Lymphoid, Nodular; Lymphoma, Large-Cell, Follicular; Lymphoma, Nodular Histiocytic; Lymphoma, Nodular, Large Follicular Center Cell; Lymphoma, Nodular, Large Follicular Center-Cell; Lymphomas, Follicular Large-Cell; Lymphomas, Nodular Histiocytic; Nodular Histiocytic Lymphoma; Nodular Histiocytic Lymphomas; Nodular Large Follicular Center Cell Lymphoma; Nodular Large Follicular Center-Cell Lymphoma
SNOMED CT: Malignant lymphoma, centroblastic, follicular (40411000); Malignant lymphoma, centroblastic type, follicular (307647008); Germinoblastic sarcoma, follicular (307647008); Malignant lymphoma, large cell, follicular (40411000); Malignant lymphoma, large cell, noncleaved, follicular (40411000); Malignant lymphoma, histiocytic, nodular (40411000); Malignant lymphoma, large cleaved cell, follicular (40411000); Malignant lymphoma, noncleaved, follicular (40411000)

Definition

An antiquated term that refers to a follicular non-Hodgkin lymphoma composed predominantly of large B-lymphocytes. [from NCI]

Professional guidelines

PubMed

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Management of adults and children receiving CAR T-cell therapy: 2021 best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) and the European Haematology Association (EHA).
Hayden PJ, Roddie C, Bader P, Basak GW, Bonig H, Bonini C, Chabannon C, Ciceri F, Corbacioglu S, Ellard R, Sanchez-Guijo F, Jäger U, Hildebrandt M, Hudecek M, Kersten MJ, Köhl U, Kuball J, Mielke S, Mohty M, Murray J, Nagler A, Rees J, Rioufol C, Saccardi R, Snowden JA, Styczynski J, Subklewe M, Thieblemont C, Topp M, Ispizua ÁU, Chen D, Vrhovac R, Gribben JG, Kröger N, Einsele H, Yakoub-Agha I
Ann Oncol 2022 Mar;33(3):259-275. Epub 2021 Dec 16 doi: 10.1016/j.annonc.2021.12.003. PMID: 34923107
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Recent clinical studies

Etiology

Update on follicular lymphoma.
Friedberg JW
Hematol Oncol 2023 Jun;41 Suppl 1(Suppl 1):43-47. doi: 10.1002/hon.3138. PMID: 37294960Free PMC Article
Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Epidemiology of Follicular Lymphoma.
Cerhan JR
Hematol Oncol Clin North Am 2020 Aug;34(4):631-646. Epub 2020 May 5 doi: 10.1016/j.hoc.2020.02.001. PMID: 32586570Free PMC Article
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Transformed follicular lymphoma.
Fischer T, Zing NPC, Chiattone CS, Federico M, Luminari S
Ann Hematol 2018 Jan;97(1):17-29. Epub 2017 Oct 18 doi: 10.1007/s00277-017-3151-2. PMID: 29043381

Diagnosis

Update on follicular lymphoma.
Friedberg JW
Hematol Oncol 2023 Jun;41 Suppl 1(Suppl 1):43-47. doi: 10.1002/hon.3138. PMID: 37294960Free PMC Article
Follicular lymphoma and marginal zone lymphoma: how many diseases?
Laurent C, Cook JR, Yoshino T, Quintanilla-Martinez L, Jaffe ES
Virchows Arch 2023 Jan;482(1):149-162. Epub 2022 Nov 17 doi: 10.1007/s00428-022-03432-2. PMID: 36394631Free PMC Article
Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Follicular lymphoma: an update on diagnosis, prognosis, and management.
Mozas P, Sorigué M, López-Guillermo A
Med Clin (Barc) 2021 Nov 12;157(9):440-448. Epub 2021 Jun 29 doi: 10.1016/j.medcli.2021.03.041. PMID: 34210513
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Therapy

Follicular lymphoma: The long and winding road leading to your cure?
Gordon MJ, Smith MR, Nastoupil LJ
Blood Rev 2023 Jan;57:100992. Epub 2022 Jul 23 doi: 10.1016/j.blre.2022.100992. PMID: 35908982
Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Dreyling M, Ghielmini M, Rule S, Salles G, Ladetto M, Tonino SH, Herfarth K, Seymour JF, Jerkeman M; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2021 Mar;32(3):298-308. Epub 2020 Nov 26 doi: 10.1016/j.annonc.2020.11.008. PMID: 33249059
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159
Follicular lymphoma.
Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J
Nat Rev Dis Primers 2019 Dec 12;5(1):83. doi: 10.1038/s41572-019-0132-x. PMID: 31831752

Prognosis

Update on follicular lymphoma.
Friedberg JW
Hematol Oncol 2023 Jun;41 Suppl 1(Suppl 1):43-47. doi: 10.1002/hon.3138. PMID: 37294960Free PMC Article
Epidemiology of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) in the United States and Western Europe: population-level projections for 2020-2025.
Kanas G, Ge W, Quek RGW, Keeven K, Nersesyan K, Jon E Arnason
Leuk Lymphoma 2022 Jan;63(1):54-63. Epub 2021 Sep 11 doi: 10.1080/10428194.2021.1975188. PMID: 34510995
Follicular lymphoma: an update on diagnosis, prognosis, and management.
Mozas P, Sorigué M, López-Guillermo A
Med Clin (Barc) 2021 Nov 12;157(9):440-448. Epub 2021 Jun 29 doi: 10.1016/j.medcli.2021.03.041. PMID: 34210513
Epidemiology of Follicular Lymphoma.
Cerhan JR
Hematol Oncol Clin North Am 2020 Aug;34(4):631-646. Epub 2020 May 5 doi: 10.1016/j.hoc.2020.02.001. PMID: 32586570Free PMC Article
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Clinical prediction guides

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Treatment patterns and outcomes of patients with relapsed or refractory follicular lymphoma receiving three or more lines of systemic therapy (LEO CReWE): a multicentre cohort study.
Casulo C, Larson MC, Lunde JJ, Habermann TM, Lossos IS, Wang Y, Nastoupil LJ, Strouse C, Chihara D, Martin P, Cohen JB, Kahl BS, Burack WR, Koff JL, Mun Y, Masaquel A, Wu M, Wei MC, Shewade A, Li J, Cerhan J, Flowers CR, Link BK, Maurer MJ
Lancet Haematol 2022 Apr;9(4):e289-e300. doi: 10.1016/S2352-3026(22)00033-3. PMID: 35358443Free PMC Article
Validation of POD24 as a robust early clinical end point of poor survival in FL from 5225 patients on 13 clinical trials.
Casulo C, Dixon JG, Le-Rademacher J, Hoster E, Hochster HS, Hiddemann W, Marcus R, Kimby E, Herold M, Sebban C, Gyan E, Foon K, Nielsen T, Vitolo U, Salles GA, Shi Q, Flowers CR
Blood 2022 Mar 17;139(11):1684-1693. doi: 10.1182/blood.2020010263. PMID: 34614146Free PMC Article
Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups.
Batlevi CL, Sha F, Alperovich A, Ni A, Smith K, Ying Z, Soumerai JD, Caron PC, Falchi L, Hamilton A, Hamlin PA, Horwitz SM, Joffe E, Kumar A, Matasar MJ, Moskowitz AJ, Moskowitz CH, Noy A, Owens C, Palomba LM, Straus D, von Keudell G, Zelenetz AD, Seshan VE, Younes A
Blood Cancer J 2020 Jul 17;10(7):74. doi: 10.1038/s41408-020-00340-z. PMID: 32678074Free PMC Article
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Recent systematic reviews

Indirect Treatment Comparisons of Mosunetuzumab With Third- and Later-Line Treatments for Relapsed/Refractory Follicular Lymphoma.
Bosch F, Kuruvilla J, Vassilakopoulos TP, Maio DD, Wei MC, Zumofen MB, Nastoupil LJ
Clin Lymphoma Myeloma Leuk 2024 Feb;24(2):105-121. Epub 2023 Sep 28 doi: 10.1016/j.clml.2023.09.007. PMID: 37981564
Lymphomas of the salivary glands: a systematic review.
Al-Khafaf AE, Al-Shahrestani F, Baysal Y, Rahbek Gjerdrum LM, Heegaard S, Pedersen LM, Homøe P
Acta Otolaryngol 2023 Jul-Aug;143(7):610-616. Epub 2023 Aug 12 doi: 10.1080/00016489.2023.2226689. PMID: 37572309
Late relapse after CAR-T cell therapy for adult patients with hematologic malignancies: A definite evidence from systematic review and meta-analysis on individual data.
Zinzi A, Gaio M, Liguori V, Cagnotta C, Paolino D, Paolisso G, Castaldo G, Nicoletti GF, Rossi F, Capuano A, Rafaniello C
Pharmacol Res 2023 Apr;190:106742. Epub 2023 Mar 22 doi: 10.1016/j.phrs.2023.106742. PMID: 36963592
A systematic review and meta-analysis of occupational exposures and risk of follicular lymphoma.
Odutola MK, Benke G, Fritschi L, Giles GG, van Leeuwen MT, Vajdic CM
Environ Res 2021 Jun;197:110887. Epub 2021 Feb 17 doi: 10.1016/j.envres.2021.110887. PMID: 33607095
Randomized controlled trials in relapsed/refractory follicular lymphoma: a systematic review and meta-analysis.
Police RL, Trask PC, Wang J, Olivares R, Khan S, Abbe A, Colosia A, Njue A, Sherril B, Ruiz-Soto R, Kaye JA, Hamadani M
J Oncol Pharm Pract 2016 Oct;22(5):666-78. Epub 2015 Aug 28 doi: 10.1177/1078155215603230. PMID: 26320127

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