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Skin Angiolipoma

MedGen UID:
1754129
•Concept ID:
C5418580
•
Neoplastic Process

Definition

An angiolipoma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Angiolipoma

Recent clinical studies

Etiology

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article
Capillary malformation associated with angiolipoma: analysis of 127 consecutive clinic patients.
Lapidoth M, Ben Amitai D, Feinmesser M, Akerman L
Am J Clin Dermatol 2008;9(6):389-92. doi: 10.2165/0128071-200809060-00005. PMID: 18973405
Limited segmental resection of symptomatic lower-extremity lymphodystrophic tissue in high-risk patients.
Oswald TM, Lineaweaver W
South Med J 2003 Jul;96(7):689-91. doi: 10.1097/01.SMJ.0000051201.32067.CF. PMID: 12940322
Cutaneous vascular proliferations. Part III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1998 Feb;38(2 Pt 1):143-75; quiz 176-8. doi: 10.1016/s0190-9622(98)70237-3. PMID: 9486670
Cytogenetic analysis of subcutaneous angiolipoma: further evidence supporting its difference from ordinary pure lipomas: a report of the CHAMP Study Group.
Sciot R, Akerman M, Dal Cin P, De Wever I, Fletcher CD, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Tallini G, Van den Berghe H, Vanni R, Willen H
Am J Surg Pathol 1997 Apr;21(4):441-4. doi: 10.1097/00000478-199704000-00010. PMID: 9130991

Diagnosis

Angiolipoma: a review of 778 lesions in 344 patients.
Kransdorf MJ, Larsen BT, Goulding KA, Cumsky JL, Hwang S, Long JR
Skeletal Radiol 2023 Mar;52(3):541-552. Epub 2022 Jun 7 doi: 10.1007/s00256-022-04075-9. PMID: 35668116
Painful cutaneous nodules.
Ruiz-Molina I, Haro-Gabaldon V, Civico-Amat V, Solís-García E
Clin Exp Dermatol 2017 Jan;42(1):104-105. Epub 2016 Dec 9 doi: 10.1111/ced.12897. PMID: 27935631
Autosomal-dominant familial angiolipomatosis.
Garib G, Siegal GP, Andea AA
Cutis 2015 Jan;95(1):E26-9. PMID: 25671454
Cutaneous angiomyolipoma.
Singh K, Pai RR, Kini H, Kini UA
Indian J Pathol Microbiol 2009 Apr-Jun;52(2):242-3. doi: 10.4103/0377-4929.48932. PMID: 19332927
Cellular angiolipoma.
Hunt SJ, Santa Cruz DJ, Barr RJ
Am J Surg Pathol 1990 Jan;14(1):75-81. doi: 10.1097/00000478-199001000-00008. PMID: 2294783

Therapy

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article
Multiple subcutaneous angiolipomas associated with new-onset diabetes mellitus.
Levitt J, Lutfi Ali SA, Sapadin A
Int J Dermatol 2002 Nov;41(11):783-5. doi: 10.1046/j.1365-4362.2002.01445.x. PMID: 12453005

Prognosis

An asymptomatic nodule on the arm of a 46-year-old man.
Boyd AS, Binhlam JQ
Am J Dermatopathol 2015 Jan;37(1):52-3, 87. doi: 10.1097/DAD.0000000000000043. PMID: 25548992
Cutaneous vascular proliferations. Part III. Malignant neoplasms, other cutaneous neoplasms with significant vascular component, and disorders erroneously considered as vascular neoplasms.
Requena L, Sangueza OP
J Am Acad Dermatol 1998 Feb;38(2 Pt 1):143-75; quiz 176-8. doi: 10.1016/s0190-9622(98)70237-3. PMID: 9486670
Cellular angiolipoma.
Kanik AB, Oh CH, Bhawan J
Am J Dermatopathol 1995 Jun;17(3):312-5. doi: 10.1097/00000372-199506000-00017. PMID: 8599444
Multiple bluish subcutaneous nodules. Multiple angiolipomas.
Haustein UF, Uhl J
Arch Dermatol 1990 May;126(5):666-7, 669. doi: 10.1001/archderm.126.5.666. PMID: 2334189

Clinical prediction guides

Solitary noninfiltrating angiolipoma on the finger, an unusual localization.
Karaali MG, Polat AK, Koku Aksu AE, Leblebici C, Gurel MS
Dermatol Online J 2019 Feb 15;25(2) PMID: 30865409
An asymptomatic nodule on the arm of a 46-year-old man.
Boyd AS, Binhlam JQ
Am J Dermatopathol 2015 Jan;37(1):52-3, 87. doi: 10.1097/DAD.0000000000000043. PMID: 25548992
Subcutaneous angiolipoma: magnetic resonance imaging features with histological correlation.
Kitagawa Y, Miyamoto M, Konno S, Makino A, Maruyama G, Takai S, Higashi N
J Nippon Med Sch 2014;81(5):313-9. doi: 10.1272/jnms.81.313. PMID: 25391700

Recent systematic reviews

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article

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