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Angiolipoma

MedGen UID:
64621
•Concept ID:
C0206632
•
Neoplastic Process
Synonym: Angiolipomas
SNOMED CT: Angiolipoma (73219006); Angiolipoma (404057003)
 
Monarch Initiative: MONDO:0006085

Definition

A lipoma with prominent vascularity. The vascular tissue is more abundant at the periphery of the tumor and contains fibrin thrombi. It occurs more frequently in younger individuals as a painful subcutaneous nodule, often on the arms. [from NCI]

Professional guidelines

PubMed

Spinal angiolipoma: etiology, imaging findings, classification, treatment, and prognosis.
Si Y, Wang Z, Pan Y, Lin G, Yu T
Eur Spine J 2014 Feb;23(2):417-25. Epub 2013 Nov 5 doi: 10.1007/s00586-013-3073-1. PMID: 24190280Free PMC Article
Lipomatous tumors of the stomach: CT findings and differential diagnosis.
Ferrozzi F, Tognini G, Bova D, Pavone P
J Comput Assist Tomogr 2000 Nov-Dec;24(6):854-8. doi: 10.1097/00004728-200011000-00006. PMID: 11105700
Size, site and clinical incidence of lipoma. Factors in the differential diagnosis of lipoma and sarcoma.
Rydholm A, Berg NO
Acta Orthop Scand 1983 Dec;54(6):929-34. doi: 10.3109/17453678308992936. PMID: 6670522

Recent clinical studies

Etiology

Microsurgical treatment for spinal epidural angiolipomas.
Yang T, Niu C
Acta Neurol Belg 2021 Apr;121(2):421-427. Epub 2019 Jul 15 doi: 10.1007/s13760-019-01192-6. PMID: 31309454
Fat-containing soft-tissue masses in children.
Sheybani EF, Eutsler EP, Navarro OM
Pediatr Radiol 2016 Dec;46(13):1760-1773. Epub 2016 Nov 19 doi: 10.1007/s00247-016-3690-z. PMID: 27866258
Fat-containing salivary gland tumors: a review.
Agaimy A
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S90-6. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0459-7. PMID: 23821211Free PMC Article
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279
Spinal extradural angiolipoma.
Krishnan VB, Law AJ, Kenwright DN
Aust N Z J Surg 1996 Mar;66(3):194-6. doi: 10.1111/j.1445-2197.1996.tb01159.x. PMID: 8639145

Diagnosis

Intraosseous angiolipoma of the mandible.
Agnone AM, Boffano P, Cavarra F, Andreis M, Ruga E, Zanellato I, Rocchetti V
J Stomatol Oral Maxillofac Surg 2023 Feb;124(1S):101329. Epub 2022 Nov 9 doi: 10.1016/j.jormas.2022.11.005. PMID: 36368613
Esophageal Lipoma and Liposarcoma: A Systematic Review.
Ferrari D, Bernardi D, Siboni S, Lazzari V, Asti E, Bonavina L
World J Surg 2021 Jan;45(1):225-234. Epub 2020 Oct 7 doi: 10.1007/s00268-020-05789-4. PMID: 33026474Free PMC Article
Gastric Angiolipoma: A Rare Entity.
Liu YJ, Karamchandani DM
Arch Pathol Lab Med 2017 Jun;141(6):862-866. doi: 10.5858/arpa.2016-0239-RS. PMID: 28557598
Fat-containing soft-tissue masses in children.
Sheybani EF, Eutsler EP, Navarro OM
Pediatr Radiol 2016 Dec;46(13):1760-1773. Epub 2016 Nov 19 doi: 10.1007/s00247-016-3690-z. PMID: 27866258
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279

Therapy

Long-term outcome of robotic partial nephrectomy for renal angiomyolipoma.
Lin CY, Yang CK, Ou YC, Chiu KY, Cheng CL, Ho HC, Wang SS, Chen CS, Li JR
Asian J Surg 2018 Mar;41(2):187-191. Epub 2016 Dec 7 doi: 10.1016/j.asjsur.2016.11.003. PMID: 27955873
Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article
Renal angiomyolipoma: long-term results following selective arterial embolization.
Ramon J, Rimon U, Garniek A, Golan G, Bensaid P, Kitrey ND, Nadu A, Dotan ZA
Eur Urol 2009 May;55(5):1155-61. Epub 2008 Apr 18 doi: 10.1016/j.eururo.2008.04.025. PMID: 18440125
Protease inhibitor-associated angiolipomatosis.
Dank JP, Colven R
J Am Acad Dermatol 2000 Jan;42(1 Pt 1):129-31. doi: 10.1016/s0190-9622(00)90021-5. PMID: 10607332
Spinal cord stimulation revisited.
Segal R, Stacey BR, Rudy TE, Baser S, Markham J
Neurol Res 1998 Jul;20(5):391-6. doi: 10.1080/01616412.1998.11740536. PMID: 9664583

Prognosis

Thoracic Spinal Angiolipomas: A Systematic Review.
Umana GE, Visocchi M, Roca E, Passanisi M, Fricia M, Tranchina MG, Tomasi SO, Nicoletti GF, Cicero S, Scalia G
J Neurol Surg A Cent Eur Neurosurg 2022 Mar;83(2):161-172. Epub 2021 Dec 20 doi: 10.1055/s-0041-1739217. PMID: 34929751
Microsurgical treatment for spinal epidural angiolipomas.
Yang T, Niu C
Acta Neurol Belg 2021 Apr;121(2):421-427. Epub 2019 Jul 15 doi: 10.1007/s13760-019-01192-6. PMID: 31309454
Angiolipoma of the Orbit.
Aljerian K, Fathaddin A, Almajed N, Kalantan H
Ophthalmic Plast Reconstr Surg 2019 May/Jun;35(3):e81-e82. doi: 10.1097/IOP.0000000000001381. PMID: 30908468
Gastric Angiolipoma: A Rare Entity.
Liu YJ, Karamchandani DM
Arch Pathol Lab Med 2017 Jun;141(6):862-866. doi: 10.5858/arpa.2016-0239-RS. PMID: 28557598
Lipomatous tumors.
Weiss SW
Monogr Pathol 1996;38:207-39. PMID: 8744279

Clinical prediction guides

Clinical features and surgical outcomes of spinal epidural angiolipomas.
Wang K, Shi L, Su Y, Wang H, Liu L
Acta Neurol Belg 2023 Feb;123(1):115-120. Epub 2021 May 4 doi: 10.1007/s13760-021-01689-z. PMID: 33948901
Microsurgical treatment for spinal epidural angiolipomas.
Yang T, Niu C
Acta Neurol Belg 2021 Apr;121(2):421-427. Epub 2019 Jul 15 doi: 10.1007/s13760-019-01192-6. PMID: 31309454
Infiltrating angiolipoma of the foot: magnetic resonance imaging features and review of the literature.
Yeo ED, Chung BM, Kim EJ, Kim WT
Skeletal Radiol 2018 Jun;47(6):859-864. Epub 2018 Jan 10 doi: 10.1007/s00256-017-2870-8. PMID: 29322209
Primary hepatic epithelioid angiomyolipoma: A malignant potential tumor which should be recognized.
Liu J, Zhang CW, Hong DF, Tao R, Chen Y, Shang MJ, Zhang YH
World J Gastroenterol 2016 May 28;22(20):4908-17. doi: 10.3748/wjg.v22.i20.4908. PMID: 27239117Free PMC Article
Renal epithelioid angiomyolipoma: a malignant disease.
Varma S, Gupta S, Talwar J, Forte F, Dhar M
J Nephrol 2011 Jan-Feb;24(1):18-22. doi: 10.5301/jn.2010.5451. PMID: 20349413

Recent systematic reviews

Thoracic Spinal Angiolipomas: A Systematic Review.
Umana GE, Visocchi M, Roca E, Passanisi M, Fricia M, Tranchina MG, Tomasi SO, Nicoletti GF, Cicero S, Scalia G
J Neurol Surg A Cent Eur Neurosurg 2022 Mar;83(2):161-172. Epub 2021 Dec 20 doi: 10.1055/s-0041-1739217. PMID: 34929751
Esophageal Lipoma and Liposarcoma: A Systematic Review.
Ferrari D, Bernardi D, Siboni S, Lazzari V, Asti E, Bonavina L
World J Surg 2021 Jan;45(1):225-234. Epub 2020 Oct 7 doi: 10.1007/s00268-020-05789-4. PMID: 33026474Free PMC Article
Positioning issues of spinal surgery during pregnancy.
Bongetta D, Versace A, De Pirro A, Gemma M, Bernardo L, Cetin I, Savasi V, Assietti R
World Neurosurg 2020 Jun;138:53-58. Epub 2020 Feb 17 doi: 10.1016/j.wneu.2020.02.044. PMID: 32081820
Spinal angiolipoma: Presentation of two cases and review of the literature for the years 2012-2017.
Apostolakis S, Karagianni A, Mitropoulos A, Mantas C, Mavridis I, Filias P, Eftychiadis C, Vlachos K
Neurocirugia (Astur : Engl Ed) 2020 Mar-Apr;31(2):76-86. Epub 2019 Jun 8 doi: 10.1016/j.neucir.2019.04.005. PMID: 31186156
Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article

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