U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign connective and soft tissue neoplasm

MedGen UID:
83866
Concept ID:
C0347481
Neoplastic Process
Synonyms: Benign Connective and Soft Tissue Neoplasm; benign connective and soft tissue neoplasm; Benign Connective and Soft Tissue Tumor; benign connective and soft tissue tumor; benign connective and soft tissue tumour; Benign Mesenchymal Cell Neoplasm; benign mesenchymal cell neoplasm; Benign Neoplasm of the Soft Tissue and Bone; benign neoplasm of the soft tissue and bone; Benign Tumor of the Soft Tissue and Bone; benign tumor of the soft tissue and bone; benign tumour of the soft tissue and bone; connective and soft tissue neoplasm, benign; connective tissue benign neoplasm; neoplasm of soft tissue; neoplasm of soft tissues; soft tissue benign neoplasm; tumor of the soft tissue; tumour of the soft tissue
 
Monarch Initiative: MONDO:0000654

Definition

A neoplasm that arises from connective and soft tissue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include lipoma, leiomyoma, fibroma, and osteoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign connective and soft tissue neoplasm

Professional guidelines

PubMed

Improta L, Tzanis D, Bouhadiba T, Abdelhafidh K, Bonvalot S
Eur J Surg Oncol 2020 Sep;46(9):1573-1579. Epub 2020 May 21 doi: 10.1016/j.ejso.2020.04.054. PMID: 32600897
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, Forti G, Toppari J, Goulis DG, Jørgensen N
Andrology 2019 Nov;7(6):778-793. Epub 2019 May 16 doi: 10.1111/andr.12636. PMID: 31099174
De La Cruz MS, Buchanan EM
Am Fam Physician 2017 Jan 15;95(2):100-107. PMID: 28084714

Recent clinical studies

Etiology

Kager M, Kager R, Fałek P, Fałek A, Szczypiór G, Niemunis-Sawicka J, Rzepecka-Wejs L, Starosławska E, Burdan F
Folia Med Cracov 2022;62(2):93-107. doi: 10.24425/fmc.2022.141702. PMID: 36256897
Sbaraglia M, Businello G, Bellan E, Fassan M, Dei Tos AP
Pathologica 2021 Jun;113(3):230-251. doi: 10.32074/1591-951X-309. PMID: 34294940Free PMC Article
Zhang Y, Kleer CG
Arch Pathol Lab Med 2016 Jul;140(7):665-71. doi: 10.5858/arpa.2016-0042-RA. PMID: 27362571
Miettinen M
Mod Pathol 2014 Jan;27 Suppl 1(Suppl 1):S17-29. doi: 10.1038/modpathol.2013.178. PMID: 24384850Free PMC Article
Salam GA
Am Fam Physician 2002 Mar 1;65(5):901-4. PMID: 11898962

Diagnosis

Kallen ME, Michal M, Meyer A, Suster DI, Olson NJ, Charville GW, Perret R, Gross JM
Am J Surg Pathol 2023 Jun 1;47(6):725-737. Epub 2023 Apr 27 doi: 10.1097/PAS.0000000000002044. PMID: 37102574
Yee EJ, Stewart CL, Clay MR, McCarter MM
Surg Clin North Am 2022 Aug;102(4):637-656. doi: 10.1016/j.suc.2022.04.006. PMID: 35952693
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197
Lam Y
FP Essent 2020 Jun;493:11-21. PMID: 32573182
Salam GA
Am Fam Physician 2002 Mar 1;65(5):901-4. PMID: 11898962

Therapy

Kager M, Kager R, Fałek P, Fałek A, Szczypiór G, Niemunis-Sawicka J, Rzepecka-Wejs L, Starosławska E, Burdan F
Folia Med Cracov 2022;62(2):93-107. doi: 10.24425/fmc.2022.141702. PMID: 36256897
Hussain SH
Curr Opin Pediatr 2020 Aug;32(4):531-538. doi: 10.1097/MOP.0000000000000922. PMID: 32692050
Metwally M, Raybould G, Cheong YC, Horne AW
Cochrane Database Syst Rev 2020 Jan 29;1(1):CD003857. doi: 10.1002/14651858.CD003857.pub4. PMID: 31995657Free PMC Article
D'Angelo SP, Mahoney MR, Van Tine BA, Atkins J, Milhem MM, Jahagirdar BN, Antonescu CR, Horvath E, Tap WD, Schwartz GK, Streicher H
Lancet Oncol 2018 Mar;19(3):416-426. Epub 2018 Jan 19 doi: 10.1016/S1470-2045(18)30006-8. PMID: 29370992Free PMC Article
Donnez J, Dolmans MM
Hum Reprod Update 2016 Nov;22(6):665-686. Epub 2016 Jul 27 doi: 10.1093/humupd/dmw023. PMID: 27466209Free PMC Article

Prognosis

Johnson CN, Ha AS, Chen E, Davidson D
J Am Acad Orthop Surg 2018 Nov 15;26(22):779-788. doi: 10.5435/JAAOS-D-17-00045. PMID: 30192249
Farshid G, Gill PG
ANZ J Surg 2017 Dec;87(12):E285-E292. Epub 2015 Mar 19 doi: 10.1111/ans.13056. PMID: 25786884
Shields CJ, Winter DC, Kirwan WO, Redmond HP
Eur J Surg Oncol 2001 Dec;27(8):701-6. doi: 10.1053/ejso.2001.1169. PMID: 11735163
Mercuri M, Picci P, Campanacci L, Rulli E
Skeletal Radiol 1995 Aug;24(6):409-16. doi: 10.1007/BF00941235. PMID: 7481896
Andrew SM, Freemont AJ
J Clin Pathol 1993 Nov;46(11):1033-5. doi: 10.1136/jcp.46.11.1033. PMID: 8254091Free PMC Article

Clinical prediction guides

Zhao G, Zhu M, Qin C, Liu X, Zhao X
J Pediatr Hematol Oncol 2020 Nov;42(8):495-498. doi: 10.1097/MPH.0000000000001603. PMID: 31764512
Felty CC, Linos K
Am J Dermatopathol 2019 Dec;41(12):879-883. doi: 10.1097/DAD.0000000000001272. PMID: 30289773
Colin GC, Gerber BL, Amzulescu M, Bogaert J
Int J Cardiovasc Imaging 2018 Nov;34(11):1789-1808. Epub 2018 Jul 4 doi: 10.1007/s10554-018-1396-z. PMID: 29974293
Krings G, Bean GR, Chen YY
Semin Diagn Pathol 2017 Sep;34(5):438-452. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.006. PMID: 28688536
Tedesco NS, Henshaw RM
J Am Acad Orthop Surg 2016 Mar;24(3):150-9. doi: 10.5435/JAAOS-D-15-00074. PMID: 26761037

Recent systematic reviews

Yu CY, Huang TW, Tam KW
Int J Surg 2022 Nov;107:106969. Epub 2022 Oct 31 doi: 10.1016/j.ijsu.2022.106969. PMID: 36328344
Sparić R, Andjić M, Babović I, Nejković L, Mitrović M, Štulić J, Pupovac M, Tinelli A
Int J Mol Sci 2022 Aug 27;23(17) doi: 10.3390/ijms23179728. PMID: 36077127Free PMC Article
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Vázquez Fernández R, Maneiro Fernández JR, Cervantes Pérez EC, Mera Varela A
Ir J Med Sci 2021 Aug;190(3):1005-1014. Epub 2020 Oct 1 doi: 10.1007/s11845-020-02378-1. PMID: 33006046
Metwally M, Raybould G, Cheong YC, Horne AW
Cochrane Database Syst Rev 2020 Jan 29;1(1):CD003857. doi: 10.1002/14651858.CD003857.pub4. PMID: 31995657Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...