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Upper extremity akinesia

MedGen UID:
1778147
•Concept ID:
C5539573
•
Finding
Synonym: Akinesia of the upper extremities
 
HPO: HP:0033412

Definition

Inability to initiate changes in activity or movement and to perform ordinary volitional movements rapidly and easily in the upper extremities. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUpper extremity akinesia

Recent clinical studies

Etiology

Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson's disease: a Distal Finger Tapping test.
Akram N, Li H, Ben-Joseph A, Budu C, Gallagher DA, Bestwick JP, Schrag A, Noyce AJ, Simonet C
Sci Rep 2022 Jan 10;12(1):386. doi: 10.1038/s41598-021-03563-7. PMID: 35013372Free PMC Article
The Progressive Supranuclear Palsy Clinical Deficits Scale.
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.
Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G
PLoS One 2014;9(4):e96260. Epub 2014 Apr 29 doi: 10.1371/journal.pone.0096260. PMID: 24781810Free PMC Article
Sonographic diagnosis of fetal upper extremity dysmorphology: significance and outcome.
Zelop C, Benacerraf B
Ultrasound Obstet Gynecol 1996 Dec;8(6):391-6. doi: 10.1046/j.1469-0705.1997.08060391.x. PMID: 9014278
Prepharyngeal dysphagia in Parkinson's disease.
Leopold NA, Kagel MC
Dysphagia 1996 Winter;11(1):14-22. doi: 10.1007/BF00385794. PMID: 8556872

Diagnosis

Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson's disease: a Distal Finger Tapping test.
Akram N, Li H, Ben-Joseph A, Budu C, Gallagher DA, Bestwick JP, Schrag A, Noyce AJ, Simonet C
Sci Rep 2022 Jan 10;12(1):386. doi: 10.1038/s41598-021-03563-7. PMID: 35013372Free PMC Article
The Progressive Supranuclear Palsy Clinical Deficits Scale.
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Structured Evaluation of Glioma Patients by an Occupational Therapist-Is Our Clinical Examination Enough?
Freyschlag CF, Kerschbaumer J, Pinggera D, Bacher G, Mur E, Thomé C
World Neurosurg 2017 Jul;103:493-500. Epub 2017 Apr 17 doi: 10.1016/j.wneu.2017.04.033. PMID: 28427970
Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.
Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G
PLoS One 2014;9(4):e96260. Epub 2014 Apr 29 doi: 10.1371/journal.pone.0096260. PMID: 24781810Free PMC Article
Sonographic diagnosis of fetal upper extremity dysmorphology: significance and outcome.
Zelop C, Benacerraf B
Ultrasound Obstet Gynecol 1996 Dec;8(6):391-6. doi: 10.1046/j.1469-0705.1997.08060391.x. PMID: 9014278

Therapy

Effects of Repetitive Transcranial Magnetic Stimulation on Motor Symptoms in Parkinson's Disease: A Meta-Analysis.
Li R, He Y, Qin W, Zhang Z, Su J, Guan Q, Chen Y, Jin L
Neurorehabil Neural Repair 2022 Jul;36(7):395-404. Epub 2022 May 26 doi: 10.1177/15459683221095034. PMID: 35616427
The Progressive Supranuclear Palsy Clinical Deficits Scale.
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Contrasting changes in cortical activation induced by acute high-frequency stimulation within the globus pallidus in Parkinson's disease.
Payoux P, Remy P, Miloudi M, Houeto JL, Stadler C, Bejjani BP, Yelnik J, Samson Y, Rascol O, Agid Y, Damier P
J Cereb Blood Flow Metab 2009 Feb;29(2):235-43. Epub 2008 Sep 10 doi: 10.1038/jcbfm.2008.107. PMID: 18781162
Parkinsonism following bilateral lesions of the globus pallidus: performance on a variety of motor tasks shows similarities with Parkinson's disease.
Kuoppamäki M, Rothwell JC, Brown RG, Quinn N, Bhatia KP, Jahanshahi M
J Neurol Neurosurg Psychiatry 2005 Apr;76(4):482-90. doi: 10.1136/jnnp.2003.020800. PMID: 15774432Free PMC Article
Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.
Wenzelburger R, Kopper F, Zhang BR, Witt K, Hamel W, Weinert D, Kuhtz-Buschbeck J, Gölge M, Illert M, Deuschl G, Krack P
Mov Disord 2003 Oct;18(10):1162-9. doi: 10.1002/mds.10501. PMID: 14534921

Prognosis

Developing and assessing a new web-based tapping test for measuring distal movement in Parkinson's disease: a Distal Finger Tapping test.
Akram N, Li H, Ben-Joseph A, Budu C, Gallagher DA, Bestwick JP, Schrag A, Noyce AJ, Simonet C
Sci Rep 2022 Jan 10;12(1):386. doi: 10.1038/s41598-021-03563-7. PMID: 35013372Free PMC Article
A system-level mathematical model of Basal Ganglia motor-circuit for kinematic planning of arm movements.
Salimi-Badr A, Ebadzadeh MM, Darlot C
Comput Biol Med 2018 Jan 1;92:78-89. Epub 2017 Nov 10 doi: 10.1016/j.compbiomed.2017.11.004. PMID: 29156412
Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.
Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G
PLoS One 2014;9(4):e96260. Epub 2014 Apr 29 doi: 10.1371/journal.pone.0096260. PMID: 24781810Free PMC Article
Sonographic diagnosis of fetal upper extremity dysmorphology: significance and outcome.
Zelop C, Benacerraf B
Ultrasound Obstet Gynecol 1996 Dec;8(6):391-6. doi: 10.1046/j.1469-0705.1997.08060391.x. PMID: 9014278

Clinical prediction guides

The Progressive Supranuclear Palsy Clinical Deficits Scale.
Piot I, Schweyer K, Respondek G, Stamelou M; DescribePSP study group; ProPSP study group; MDS-endorsed PSP study group, Sckopke P, Schenk T, Goetz CG, Stebbins GT, Höglinger GU
Mov Disord 2020 Apr;35(4):650-661. Epub 2020 Jan 17 doi: 10.1002/mds.27964. PMID: 31951049
Tests of manual dexterity and speed in Parkinson's disease: Not all measure the same.
Růžička E, Krupička R, Zárubová K, Rusz J, Jech R, Szabó Z
Parkinsonism Relat Disord 2016 Jul;28:118-23. Epub 2016 May 7 doi: 10.1016/j.parkreldis.2016.05.009. PMID: 27185294
Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.
Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G
PLoS One 2014;9(4):e96260. Epub 2014 Apr 29 doi: 10.1371/journal.pone.0096260. PMID: 24781810Free PMC Article
Prepharyngeal dysphagia in Parkinson's disease.
Leopold NA, Kagel MC
Dysphagia 1996 Winter;11(1):14-22. doi: 10.1007/BF00385794. PMID: 8556872
Differential effects of cortical lesions in humans.
Freund HJ
Ciba Found Symp 1987;132:269-81. doi: 10.1002/9780470513545.ch16. PMID: 3322719

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