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Lacrimal Drainage System Non-Hodgkin Lymphoma

MedGen UID:
1781844
•Concept ID:
C5446560
•
Neoplastic Process
Synonyms: Lacrimal Drainage System Lymphoma; Lacrimal Sac Lymphoma; Lacrimal Sac Non-Hodgkin Lymphoma; Primary Lacrimal Drainage System Lymphoma; Primary Lacrimal Drainage System Non-Hodgkin Lymphoma; Primary Lacrimal Sac Lymphoma; Primary Lacrimal Sac Non-Hodgkin Lymphoma

Definition

A non-Hodgkin lymphoma that arises from the lacrimal sac. The majority of cases are of B-cell type. The most common subtypes are mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma. [from NCI]

Recent clinical studies

Etiology

NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature.
Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R
Ophthalmic Plast Reconstr Surg 2023 Jul-Aug 01;39(4):316-327. Epub 2023 Jan 24 doi: 10.1097/IOP.0000000000002317. PMID: 36692957
Clinical profile and management outcomes of lacrimal drainage system malignancies.
Alam MS, Mukherjee B, Krishnakumar S
Orbit 2022 Aug;41(4):429-436. Epub 2021 May 21 doi: 10.1080/01676830.2021.1925932. PMID: 34018461
Epiphora as the presenting sign of relapsed non-Hodgkin lymphoma in a child with Bruton agammaglobulinemia.
Gokce G, Ceylan OM, Uysal Y, Yildizoglu U, Atas E, Kurt B
Eur J Ophthalmol 2015 Jan-Feb;25(1):65-7. Epub 2014 May 8 doi: 10.5301/ejo.5000487. PMID: 24832039
Involvement of the lacrimal drainage system by leukemia or lymphoma.
Yip CC, Bartley GB, Habermann TM, Garrity JA
Ophthalmic Plast Reconstr Surg 2002 Jul;18(4):242-6. doi: 10.1097/00002341-200207000-00002. PMID: 12142754

Diagnosis

NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature.
Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R
Ophthalmic Plast Reconstr Surg 2023 Jul-Aug 01;39(4):316-327. Epub 2023 Jan 24 doi: 10.1097/IOP.0000000000002317. PMID: 36692957
Clinical profile and management outcomes of lacrimal drainage system malignancies.
Alam MS, Mukherjee B, Krishnakumar S
Orbit 2022 Aug;41(4):429-436. Epub 2021 May 21 doi: 10.1080/01676830.2021.1925932. PMID: 34018461
Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the lacrimal drainage system in two pediatric patients.
Ucgul AY, Tarlan B, Gocun PU, Konuk O
Eur J Ophthalmol 2020 May;30(3):NP18-NP23. Epub 2019 Mar 12 doi: 10.1177/1120672119837085. PMID: 30862184
Primary lymphoma of nasolacrimal drainage system: a case report and literature review.
Gao HW, Lee HS, Lin YS, Sheu LF
Am J Otolaryngol 2005 Sep-Oct;26(5):356-9. doi: 10.1016/j.amjoto.2005.02.011. PMID: 16137539
Involvement of the lacrimal drainage system by leukemia or lymphoma.
Yip CC, Bartley GB, Habermann TM, Garrity JA
Ophthalmic Plast Reconstr Surg 2002 Jul;18(4):242-6. doi: 10.1097/00002341-200207000-00002. PMID: 12142754

Therapy

Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the lacrimal drainage system in two pediatric patients.
Ucgul AY, Tarlan B, Gocun PU, Konuk O
Eur J Ophthalmol 2020 May;30(3):NP18-NP23. Epub 2019 Mar 12 doi: 10.1177/1120672119837085. PMID: 30862184
Primary lymphoma of nasolacrimal drainage system: a case report and literature review.
Gao HW, Lee HS, Lin YS, Sheu LF
Am J Otolaryngol 2005 Sep-Oct;26(5):356-9. doi: 10.1016/j.amjoto.2005.02.011. PMID: 16137539
Involvement of the lacrimal drainage system by leukemia or lymphoma.
Yip CC, Bartley GB, Habermann TM, Garrity JA
Ophthalmic Plast Reconstr Surg 2002 Jul;18(4):242-6. doi: 10.1097/00002341-200207000-00002. PMID: 12142754

Prognosis

NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature.
Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R
Ophthalmic Plast Reconstr Surg 2023 Jul-Aug 01;39(4):316-327. Epub 2023 Jan 24 doi: 10.1097/IOP.0000000000002317. PMID: 36692957
Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the lacrimal drainage system in two pediatric patients.
Ucgul AY, Tarlan B, Gocun PU, Konuk O
Eur J Ophthalmol 2020 May;30(3):NP18-NP23. Epub 2019 Mar 12 doi: 10.1177/1120672119837085. PMID: 30862184
Primary lymphoma of nasolacrimal drainage system: a case report and literature review.
Gao HW, Lee HS, Lin YS, Sheu LF
Am J Otolaryngol 2005 Sep-Oct;26(5):356-9. doi: 10.1016/j.amjoto.2005.02.011. PMID: 16137539

Recent systematic reviews

NK/T-cell Lymphoma With Orbital Involvement: A Case Report and Systematic Review of the Literature.
Dhodapkar RM, Spadaro JZ, Heng JS, Sinard JH, Lee YH, Habib LA, Pointdujour-Lim R
Ophthalmic Plast Reconstr Surg 2023 Jul-Aug 01;39(4):316-327. Epub 2023 Jan 24 doi: 10.1097/IOP.0000000000002317. PMID: 36692957

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