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Abnormal circulating lipoprotein lipase concentration

MedGen UID:
1788301
•Concept ID:
C5539627
•
Finding
HPO: HP:0033477

Definition

A deviation from the normal concentration of lipoprotein lipase in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating lipoprotein lipase concentration

Recent clinical studies

Etiology

Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.
Mesotten D, Swinnen JV, Vanderhoydonc F, Wouters PJ, Van den Berghe G
J Clin Endocrinol Metab 2004 Jan;89(1):219-26. doi: 10.1210/jc.2003-030760. PMID: 14715853
Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters.
Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N
Clin Endocrinol (Oxf) 2001 Apr;54(4):447-53. doi: 10.1046/j.1365-2265.2001.01228.x. PMID: 11318779
Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism.
Packard CJ, Shepherd J, Lindsay GM, Gaw A, Taskinen MR
J Clin Endocrinol Metab 1993 May;76(5):1209-16. doi: 10.1210/jcem.76.5.8496312. PMID: 8496312
Lipoprotein metabolism in normal and uremic patients.
Goldberg IJ
Am J Kidney Dis 1993 Jan;21(1):87-90. doi: 10.1016/s0272-6386(12)80728-1. PMID: 8418633
Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.
Coppack SW, Evans RD, Fisher RM, Frayn KN, Gibbons GF, Humphreys SM, Kirk ML, Potts JL, Hockaday TD
Metabolism 1992 Mar;41(3):264-72. doi: 10.1016/0026-0495(92)90269-g. PMID: 1542265

Diagnosis

Contribution of triglyceride-rich lipoproteins to plasma free fatty acids.
Miles JM, Nelson RH
Horm Metab Res 2007 Oct;39(10):726-9. doi: 10.1055/s-2007-990273. PMID: 17952834
Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.
Coppack SW, Evans RD, Fisher RM, Frayn KN, Gibbons GF, Humphreys SM, Kirk ML, Potts JL, Hockaday TD
Metabolism 1992 Mar;41(3):264-72. doi: 10.1016/0026-0495(92)90269-g. PMID: 1542265

Therapy

Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.
Mesotten D, Swinnen JV, Vanderhoydonc F, Wouters PJ, Van den Berghe G
J Clin Endocrinol Metab 2004 Jan;89(1):219-26. doi: 10.1210/jc.2003-030760. PMID: 14715853
Acute dyslipoproteinemia induced by interleukin-2: lecithin:cholesteryl acyltransferase, lipoprotein lipase, and hepatic lipase deficiencies.
Kwong LK, Ridinger DN, Bandhauer M, Ward JH, Samlowski WE, Iverius PH, Pritchard H, Wilson DE
J Clin Endocrinol Metab 1997 May;82(5):1572-81. doi: 10.1210/jcem.82.5.3937. PMID: 9141552
Thyroid replacement therapy and its influence on postheparin plasma lipases and apolipoprotein-B metabolism in hypothyroidism.
Packard CJ, Shepherd J, Lindsay GM, Gaw A, Taskinen MR
J Clin Endocrinol Metab 1993 May;76(5):1209-16. doi: 10.1210/jcem.76.5.8496312. PMID: 8496312
Improvement of plasma lipoprotein profiles during high-flux dialysis.
Seres DS, Strain GW, Hashim SA, Goldberg IJ, Levin NW
J Am Soc Nephrol 1993 Jan;3(7):1409-15. doi: 10.1681/ASN.V371409. PMID: 8439653

Prognosis

Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters.
Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N
Clin Endocrinol (Oxf) 2001 Apr;54(4):447-53. doi: 10.1046/j.1365-2265.2001.01228.x. PMID: 11318779
Acute dyslipoproteinemia induced by interleukin-2: lecithin:cholesteryl acyltransferase, lipoprotein lipase, and hepatic lipase deficiencies.
Kwong LK, Ridinger DN, Bandhauer M, Ward JH, Samlowski WE, Iverius PH, Pritchard H, Wilson DE
J Clin Endocrinol Metab 1997 May;82(5):1572-81. doi: 10.1210/jcem.82.5.3937. PMID: 9141552

Clinical prediction guides

Turning over our fat stores: the key to metabolic health Blaxter Award Lecture 2018.
Frayn KN
Proc Nutr Soc 2019 Aug;78(3):398-406. Epub 2018 Oct 29 doi: 10.1017/S0029665118002598. PMID: 30370886
Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters.
Pirwany IR, Fleming R, Greer IA, Packard CJ, Sattar N
Clin Endocrinol (Oxf) 2001 Apr;54(4):447-53. doi: 10.1046/j.1365-2265.2001.01228.x. PMID: 11318779
Acute dyslipoproteinemia induced by interleukin-2: lecithin:cholesteryl acyltransferase, lipoprotein lipase, and hepatic lipase deficiencies.
Kwong LK, Ridinger DN, Bandhauer M, Ward JH, Samlowski WE, Iverius PH, Pritchard H, Wilson DE
J Clin Endocrinol Metab 1997 May;82(5):1572-81. doi: 10.1210/jcem.82.5.3937. PMID: 9141552
Lipoprotein metabolism in normal and uremic patients.
Goldberg IJ
Am J Kidney Dis 1993 Jan;21(1):87-90. doi: 10.1016/s0272-6386(12)80728-1. PMID: 8418633
Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein.
Demant T, Carlson LA, Holmquist L, Karpe F, Nilsson-Ehle P, Packard CJ, Shepherd J
J Lipid Res 1988 Dec;29(12):1603-11. PMID: 3244012

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