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Recurrent Malignant Scrotal Neoplasm

MedGen UID:
1792151
•Concept ID:
C5555710
•
Neoplastic Process

Definition

The reemergence of a malignant scrotal neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Malignant Scrotal Neoplasm

Professional guidelines

PubMed

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Laser treatment of condylomata acuminata.
Stein BS
J Urol 1986 Sep;136(3):593-4. doi: 10.1016/s0022-5347(17)44983-4. PMID: 3735534

Recent clinical studies

Etiology

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Primary testicular lymphoma.
Vitolo U, Ferreri AJ, Zucca E
Crit Rev Oncol Hematol 2008 Feb;65(2):183-9. Epub 2007 Oct 24 doi: 10.1016/j.critrevonc.2007.08.005. PMID: 17962036
Extramammary Paget's disease.
Mehta NJ, Torno R, Sorra T
South Med J 2000 Jul;93(7):713-5. PMID: 10923963

Diagnosis

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Extramammary Paget disease.
Hartman R, Chu J, Patel R, Meehan S, Stein JA
Dermatol Online J 2011 Oct 15;17(10):4. PMID: 22031630
Primary testicular lymphoma.
Vitolo U, Ferreri AJ, Zucca E
Crit Rev Oncol Hematol 2008 Feb;65(2):183-9. Epub 2007 Oct 24 doi: 10.1016/j.critrevonc.2007.08.005. PMID: 17962036
Extramammary Paget's disease.
Mehta NJ, Torno R, Sorra T
South Med J 2000 Jul;93(7):713-5. PMID: 10923963

Therapy

HPV-related diseases in male patients: an underestimated conundrum.
Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654Free PMC Article
Mixed extragonadal germ cell tumour of the prostate.
Antunes HP, Almeida R, Sousa V, Figueiredo A
BMJ Case Rep 2018 Jul 10;2018 doi: 10.1136/bcr-2017-223603. PMID: 29991542Free PMC Article
Primary genitourinary melanoma.
Nguyen AT, Kavolius JP, Russo P, Grimaldi G, Katz J, Brady MS
Urology 2001 Apr;57(4):633-8. doi: 10.1016/s0090-4295(00)01107-9. PMID: 11306366
Malignant mesothelioma of the tunica vaginalis testis.
Carp NZ, Petersen RO, Kusiak JF, Greenberg RE
J Urol 1990 Dec;144(6):1475-8. doi: 10.1016/s0022-5347(17)39773-2. PMID: 2146405
Testicular cancer in cryptorchids.
Batata MA, Chu FC, Hilaris BS, Whitmore WF, Golbey RB
Cancer 1982 Mar 1;49(5):1023-30. doi: 10.1002/1097-0142(19820301)49:5<1023::aid-cncr2820490528>3.0.co;2-m. PMID: 6120755

Prognosis

Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Primary testicular leiomyosarcoma.
Bostanci Y, Ozden E, Akdeniz E, Kazzazi A, Kandemir B, Yakupoglu YK, Djavan B
Can J Urol 2013 Apr;20(2):6730-3. PMID: 23587515
Malignant fibrous histiocytoma of the spermatic cord: case report and literature review.
Xu LW, Yu YL, Li GH
J Int Med Res 2012;40(2):816-23. doi: 10.1177/147323001204000249. PMID: 22613448
Extramammary Paget's disease.
Mehta NJ, Torno R, Sorra T
South Med J 2000 Jul;93(7):713-5. PMID: 10923963
Intrascrotal adenomatoid tumors.
Tammela TL, Karttunen TJ, Mäkäräinen HP, Hellström PA, Mattila SI, Kontturi MJ
J Urol 1991 Jul;146(1):61-5. doi: 10.1016/s0022-5347(17)37715-7. PMID: 2056607

Clinical prediction guides

Paratesticular cellular angiofibroma: a case report.
Murashima T, Kida K, Gi T, Hida T, Fujii M, Nagai T, Takamori H, Mukai S, Sato Y, Kamoto T
J Med Case Rep 2024 Apr 11;18(1):170. doi: 10.1186/s13256-024-04499-y. PMID: 38600580Free PMC Article
18F-FDG and 68Ga-PSMA PET/CT in Paratesticular Mesothelioma.
Kalantari F, Schweighofer-Zwink G, Rendl G, Pirich C, Beheshti M
Clin Nucl Med 2024 Apr 1;49(4):332. doi: 10.1097/RLU.0000000000005123. PMID: 38427957
HPV-related diseases in male patients: an underestimated conundrum.
Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654Free PMC Article
Electron radiotherapy for EMPD of penis and scrotum.
Lee HK, Youn SM, Shim SJ, Lee MJ
J Cancer Res Ther 2023 Jan 1;19(Suppl 2):S998-S1001. Epub 2023 Apr 28 doi: 10.4103/jcrt.jcrt_506_21. PMID: 38384101
A clinical series and literature review of the management of inguinal nodal metastases in patients with primary extramammary Paget disease of the scrotum.
Koh YX, Tay TK, Xu S, Lee CM, Teo MC
Asian J Surg 2015 Jan;38(1):40-6. Epub 2014 Oct 16 doi: 10.1016/j.asjsur.2014.08.001. PMID: 25444176

Recent systematic reviews

Testis-sparing surgery and scrotal violation for testicular masses suspicious for malignancy: A systematic review and meta-analysis.
Patel HD, Gupta M, Cheaib JG, Sharma R, Zhang A, Bass EB, Pierorazio PM
Urol Oncol 2020 May;38(5):344-353. Epub 2020 Mar 17 doi: 10.1016/j.urolonc.2020.02.023. PMID: 32192891
Systematic Review of Surgical Treatment and Outcomes After Local Surgery of Primary Cutaneous Melanomas of the Penis and Scrotum.
Bittar JM, Bittar PG, Wan MT, Kovell RC, Guzzo TJ, Shin TM, Etzkorn JR, Sobanko JF, Miller CJ
Dermatol Surg 2018 Sep;44(9):1159-1169. doi: 10.1097/DSS.0000000000001579. PMID: 29985865
Scrotal Melanoma: A Systematic Review of Presentation, Treatment, and Outcomes.
Zikry J, Chapman LW, Korta DZ, Smith J
Dermatol Surg 2017 Jun;43(6):765-770. doi: 10.1097/DSS.0000000000001072. PMID: 28291064
Adult inguinoscrotal sarcomas: outcome analysis of 21 cases, systematic review of the literature and meta-analysis.
Froehner M, Koch R, Lossnitzer A, Schober RR, Schuler M, Wirth MP
World J Urol 2014 Apr;32(2):445-51. Epub 2013 Jul 9 doi: 10.1007/s00345-013-1124-1. PMID: 23836016

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