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Muscle Invasive Bladder Urothelial Carcinoma

MedGen UID:
1792935
•Concept ID:
C5556494
•
Neoplastic Process

Definition

A bladder urothelial carcinoma invading into the bladder muscularis propria. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMuscle Invasive Bladder Urothelial Carcinoma

Professional guidelines

PubMed

A model of thermotherapy treatment for bladder cancer.
Sadee C, Kashdan E
Math Biosci Eng 2016 Dec 1;13(6):1169-1183. doi: 10.3934/mbe.2016037. PMID: 27775374
New insights in intravesical treatment for intermediate- and high-risk non-muscle-invasive urothelial bladder carcinoma.
Babjuk M
Eur Urol 2010 May;57(5):774-6; author reply 776-7. Epub 2010 Jan 14 doi: 10.1016/j.eururo.2010.01.004. PMID: 20080332

Recent clinical studies

Etiology

Neoadjuvant Cisplatin-Based Chemotherapy Followed by Selective Bladder Preservation Chemoradiotherapy in Muscle-Invasive Urothelial Carcinoma of the Bladder: Post Hoc Analysis of Two Prospective Studies.
Cho SW, Lim SH, Kwon GY, Kim CK, Park W, Pyo H, Chung JH, Song W, Sung HH, Jeong BC, Park SH
Cancer Res Treat 2024 Jul;56(3):893-897. Epub 2024 Feb 15 doi: 10.4143/crt.2024.015. PMID: 38374699Free PMC Article
Neoadjuvant Nivolumab Plus Gemcitabine/Cisplatin Chemotherapy in Muscle-Invasive Urothelial Carcinoma of the Bladder.
Kim H, Jeong BC, Hong J, Kwon GY, Kim CK, Park W, Pyo H, Song W, Sung HH, Hong JY, Park SH
Cancer Res Treat 2023 Apr;55(2):636-642. Epub 2022 Oct 6 doi: 10.4143/crt.2022.343. PMID: 36228654Free PMC Article
Impact of sex on outcomes after surgery for non-muscle-invasive and muscle-invasive bladder urothelial carcinoma: a systematic review and meta-analysis.
Mori K, Yanagisawa T, Katayama S, Laukhtina E, Pradere B, Mostafaei H, Quhal F, Rajwa P, Moschini M, Soria F, D'andrea D, Abufaraj M, Albisinni S, Krajewski W, Fukuokaya W, Miki J, Kimura T, Egawa S, Teoh JY, Shariat SF; European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU)
World J Urol 2023 Apr;41(4):909-919. Epub 2022 Aug 13 doi: 10.1007/s00345-022-04116-x. PMID: 35963957Free PMC Article
A novel prognostic biomarker for muscle invasive bladder urothelial carcinoma based on 11 DNA methylation signature.
Feng Y, Jiang Y, Feng Q, Xu L, Jiang Y, Meng F, Shu X
Cancer Biol Ther 2020 Dec 1;21(12):1119-1127. Epub 2020 Nov 5 doi: 10.1080/15384047.2020.1833811. PMID: 33151129Free PMC Article
Young age increases the risk of lymph-node metastasis in patients with muscle-invasive bladder urothelial carcinoma.
Tian Z, Meng L, Wang X, Diao T, Hu M, Wang M, Liu M, Wang J
BMC Cancer 2020 Sep 4;20(1):851. doi: 10.1186/s12885-020-07354-7. PMID: 32887577Free PMC Article

Diagnosis

Differential expression of WNT5A long and short isoforms in non-muscle-invasive bladder urothelial carcinoma.
Strope AM, Phillips C, Khadgi S, Jenkinson SA, Coschigano KT, Malgor R
Histol Histopathol 2024 Jun;39(6):715-727. Epub 2024 Feb 23 doi: 10.14670/HH-18-723. PMID: 38445662
TRPS1 expression in primary and metastatic prostatic adenocarcinoma, muscle invasive bladder urothelial carcinoma, and breast carcinoma: Is TRPS1 truly specific and sensitive for a breast primary?
Bachert SE, Di J, Zhang S, Short HE, Piecoro DW, McDonald RJ, Myint ZW, Hensley PJ, Allison DB
Hum Pathol 2024 Jan;143:42-49. Epub 2023 Dec 3 doi: 10.1016/j.humpath.2023.11.012. PMID: 38052269Free PMC Article
A Nomogram Model to Predict Recurrence of Non-Muscle Invasive Bladder Urothelial Carcinoma After Resection Based on Clinical Parameters and Immunohistochemical Markers.
Pi J, Xiong Y, Liu C, Liao J, Liu J, Li C, Fu W, Zhao T
J Invest Surg 2022 May;35(5):1186-1194. Epub 2021 Dec 16 doi: 10.1080/08941939.2021.2017080. PMID: 34913802
Bioinformatic Identification of Potential Hub Genes in Muscle-Invasive Bladder Urothelial Carcinoma.
Guo C, Shao T, Wei D, Li C, Liu F, Li M, Gao Z, Bao G
Cell Transplant 2020 Jan-Dec;29:963689720965178. doi: 10.1177/0963689720965178. PMID: 33035117Free PMC Article
Young age increases the risk of lymph-node metastasis in patients with muscle-invasive bladder urothelial carcinoma.
Tian Z, Meng L, Wang X, Diao T, Hu M, Wang M, Liu M, Wang J
BMC Cancer 2020 Sep 4;20(1):851. doi: 10.1186/s12885-020-07354-7. PMID: 32887577Free PMC Article

Therapy

Neoadjuvant Cisplatin-Based Chemotherapy Followed by Selective Bladder Preservation Chemoradiotherapy in Muscle-Invasive Urothelial Carcinoma of the Bladder: Post Hoc Analysis of Two Prospective Studies.
Cho SW, Lim SH, Kwon GY, Kim CK, Park W, Pyo H, Chung JH, Song W, Sung HH, Jeong BC, Park SH
Cancer Res Treat 2024 Jul;56(3):893-897. Epub 2024 Feb 15 doi: 10.4143/crt.2024.015. PMID: 38374699Free PMC Article
HER2/neu expression status of post BCG recurrent non-muscle-invasive bladder urothelial carcinomas in relation to their primary ones.
Ali MY, Aboelsaad AY, Abdel Gawad AM, Abouelgreed TA, El Gammal AA, Ghoneimy OM, El-Dydamony EM, Alrefaey AA, Mohamed E, Azzam S, Abdulmohaymen A, Mohammed Y, Abdelwahed MS, Elsayed AFA, Fathi BA, Abd Alrahim NM, Farag AS, Mahmoud AR, Mohamed HI, Horsu S, Hasan A
Arch Ital Urol Androl 2023 May 30;95(2):11313. doi: 10.4081/aiua.2023.11313. PMID: 37254927
Neoadjuvant Nivolumab Plus Gemcitabine/Cisplatin Chemotherapy in Muscle-Invasive Urothelial Carcinoma of the Bladder.
Kim H, Jeong BC, Hong J, Kwon GY, Kim CK, Park W, Pyo H, Song W, Sung HH, Hong JY, Park SH
Cancer Res Treat 2023 Apr;55(2):636-642. Epub 2022 Oct 6 doi: 10.4143/crt.2022.343. PMID: 36228654Free PMC Article
PD-1 inhibitor toripalimab with gemcitabine as a neoadjuvant therapy for muscle-invasive bladder urothelial carcinoma: A case report.
Yin H, Yongkang M, Bao G, Shiming Z, Chaohong H, Tiejun Y
Medicine (Baltimore) 2022 Jan 14;101(2):e28591. doi: 10.1097/MD.0000000000028591. PMID: 35029241Free PMC Article
Prognostic value of T1 substaging on oncological outcomes in patients with non-muscle-invasive bladder urothelial carcinoma: a systematic literature review and meta-analysis.
Kardoust Parizi M, Enikeev D, Glybochko PV, Seebacher V, Janisch F, Fajkovic H, Chłosta PL, Shariat SF
World J Urol 2020 Jun;38(6):1437-1449. Epub 2019 Sep 6 doi: 10.1007/s00345-019-02936-y. PMID: 31493109Free PMC Article

Prognosis

Impact of sex on outcomes after surgery for non-muscle-invasive and muscle-invasive bladder urothelial carcinoma: a systematic review and meta-analysis.
Mori K, Yanagisawa T, Katayama S, Laukhtina E, Pradere B, Mostafaei H, Quhal F, Rajwa P, Moschini M, Soria F, D'andrea D, Abufaraj M, Albisinni S, Krajewski W, Fukuokaya W, Miki J, Kimura T, Egawa S, Teoh JY, Shariat SF; European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU)
World J Urol 2023 Apr;41(4):909-919. Epub 2022 Aug 13 doi: 10.1007/s00345-022-04116-x. PMID: 35963957Free PMC Article
A Nomogram Model to Predict Recurrence of Non-Muscle Invasive Bladder Urothelial Carcinoma After Resection Based on Clinical Parameters and Immunohistochemical Markers.
Pi J, Xiong Y, Liu C, Liao J, Liu J, Li C, Fu W, Zhao T
J Invest Surg 2022 May;35(5):1186-1194. Epub 2021 Dec 16 doi: 10.1080/08941939.2021.2017080. PMID: 34913802
A novel prognostic biomarker for muscle invasive bladder urothelial carcinoma based on 11 DNA methylation signature.
Feng Y, Jiang Y, Feng Q, Xu L, Jiang Y, Meng F, Shu X
Cancer Biol Ther 2020 Dec 1;21(12):1119-1127. Epub 2020 Nov 5 doi: 10.1080/15384047.2020.1833811. PMID: 33151129Free PMC Article
Identifying Potential Prognostic Markers for Muscle-Invasive Bladder Urothelial Carcinoma by Weighted Gene Co-Expression Network Analysis.
Feng Y, Jiang Y, Wen T, Meng F, Shu X
Pathol Oncol Res 2020 Apr;26(2):1063-1072. Epub 2019 Apr 22 doi: 10.1007/s12253-019-00657-6. PMID: 31011911
Overexpression of Eg5 predicts unfavorable prognosis in non-muscle invasive bladder urothelial carcinoma.
Ding S, Xing N, Lu J, Zhang H, Nishizawa K, Liu S, Yuan X, Qin Y, Liu Y, Ogawa O, Nishiyama H
Int J Urol 2011 Jun;18(6):432-8. Epub 2011 Mar 30 doi: 10.1111/j.1442-2042.2011.02751.x. PMID: 21449971

Clinical prediction guides

TRPS1 expression in primary and metastatic prostatic adenocarcinoma, muscle invasive bladder urothelial carcinoma, and breast carcinoma: Is TRPS1 truly specific and sensitive for a breast primary?
Bachert SE, Di J, Zhang S, Short HE, Piecoro DW, McDonald RJ, Myint ZW, Hensley PJ, Allison DB
Hum Pathol 2024 Jan;143:42-49. Epub 2023 Dec 3 doi: 10.1016/j.humpath.2023.11.012. PMID: 38052269Free PMC Article
A Nomogram Model to Predict Recurrence of Non-Muscle Invasive Bladder Urothelial Carcinoma After Resection Based on Clinical Parameters and Immunohistochemical Markers.
Pi J, Xiong Y, Liu C, Liao J, Liu J, Li C, Fu W, Zhao T
J Invest Surg 2022 May;35(5):1186-1194. Epub 2021 Dec 16 doi: 10.1080/08941939.2021.2017080. PMID: 34913802
A novel prognostic biomarker for muscle invasive bladder urothelial carcinoma based on 11 DNA methylation signature.
Feng Y, Jiang Y, Feng Q, Xu L, Jiang Y, Meng F, Shu X
Cancer Biol Ther 2020 Dec 1;21(12):1119-1127. Epub 2020 Nov 5 doi: 10.1080/15384047.2020.1833811. PMID: 33151129Free PMC Article
Identifying Potential Prognostic Markers for Muscle-Invasive Bladder Urothelial Carcinoma by Weighted Gene Co-Expression Network Analysis.
Feng Y, Jiang Y, Wen T, Meng F, Shu X
Pathol Oncol Res 2020 Apr;26(2):1063-1072. Epub 2019 Apr 22 doi: 10.1007/s12253-019-00657-6. PMID: 31011911
Prognostic Value of Beta-Tubulin-3 and c-Myc in Muscle Invasive Urothelial Carcinoma of the Bladder.
Massari F, Bria E, Ciccarese C, Munari E, Modena A, Zambonin V, Sperduti I, Artibani W, Cheng L, Martignoni G, Tortora G, Brunelli M
PLoS One 2015;10(6):e0127908. Epub 2015 Jun 5 doi: 10.1371/journal.pone.0127908. PMID: 26046361Free PMC Article

Recent systematic reviews

Impact of sex on outcomes after surgery for non-muscle-invasive and muscle-invasive bladder urothelial carcinoma: a systematic review and meta-analysis.
Mori K, Yanagisawa T, Katayama S, Laukhtina E, Pradere B, Mostafaei H, Quhal F, Rajwa P, Moschini M, Soria F, D'andrea D, Abufaraj M, Albisinni S, Krajewski W, Fukuokaya W, Miki J, Kimura T, Egawa S, Teoh JY, Shariat SF; European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU)
World J Urol 2023 Apr;41(4):909-919. Epub 2022 Aug 13 doi: 10.1007/s00345-022-04116-x. PMID: 35963957Free PMC Article
Prognostic value of T1 substaging on oncological outcomes in patients with non-muscle-invasive bladder urothelial carcinoma: a systematic literature review and meta-analysis.
Kardoust Parizi M, Enikeev D, Glybochko PV, Seebacher V, Janisch F, Fajkovic H, Chłosta PL, Shariat SF
World J Urol 2020 Jun;38(6):1437-1449. Epub 2019 Sep 6 doi: 10.1007/s00345-019-02936-y. PMID: 31493109Free PMC Article

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