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Elevated circulating medium-chain acylcarnitine concentration

MedGen UID:
1853261
•Concept ID:
C5872918
•
Finding
HPO: HP:0035017

Definition

Concentration of medium-chain acylcarnitine in the blood circulation above the upper limit of normal. Acylcarnitines are classified according to the number of carbon atoms in the acyl-chain. Medium-chain acylcarnitines have between six and twelve carbon atoms in the acyl-chain (C6-C12), [from HPO]

Recent clinical studies

Etiology

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Huffman KM, Shah SH, Stevens RD, Bain JR, Muehlbauer M, Slentz CA, Tanner CJ, Kuchibhatla M, Houmard JA, Newgard CB, Kraus WE
Diabetes Care 2009 Sep;32(9):1678-83. Epub 2009 Jun 5 doi: 10.2337/dc08-2075. PMID: 19502541Free PMC Article

Diagnosis

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Huffman KM, Shah SH, Stevens RD, Bain JR, Muehlbauer M, Slentz CA, Tanner CJ, Kuchibhatla M, Houmard JA, Newgard CB, Kraus WE
Diabetes Care 2009 Sep;32(9):1678-83. Epub 2009 Jun 5 doi: 10.2337/dc08-2075. PMID: 19502541Free PMC Article

Prognosis

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Huffman KM, Shah SH, Stevens RD, Bain JR, Muehlbauer M, Slentz CA, Tanner CJ, Kuchibhatla M, Houmard JA, Newgard CB, Kraus WE
Diabetes Care 2009 Sep;32(9):1678-83. Epub 2009 Jun 5 doi: 10.2337/dc08-2075. PMID: 19502541Free PMC Article

Clinical prediction guides

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women.
Huffman KM, Shah SH, Stevens RD, Bain JR, Muehlbauer M, Slentz CA, Tanner CJ, Kuchibhatla M, Houmard JA, Newgard CB, Kraus WE
Diabetes Care 2009 Sep;32(9):1678-83. Epub 2009 Jun 5 doi: 10.2337/dc08-2075. PMID: 19502541Free PMC Article

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