U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pre-Excitation, Mahaim-Type

MedGen UID:
18609
•Concept ID:
C0032916
•
Disease or Syndrome
Synonyms: Mahaim Type Pre Excitation; Mahaim Type Preexcitation; Mahaim-Type Pre-Excitation; Mahaim-Type Preexcitation; Pre Excitation, Mahaim Type; Preexcitation, Mahaim-Type

Definition

A form of ventricular pre-excitation characterized by a normal PR interval and a long QRS interval with an initial slow deflection (delta wave). In this syndrome, the atrial impulse travel to the ventricle via the MAHAIM FIBERS which connect ATRIOVENTRICULAR NODE directly to the right ventricle wall (NODOVENTRICULAR ACCESSORY PATHWAY) or to the RIGHT BUNDLE BRANCH OF HIS (nodofascicular accessory pathway). [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPre-Excitation, Mahaim-Type

Professional guidelines

PubMed

Electrocardiogram during tachycardia in patients with anterograde conduction over a Mahaim fiber: old criteria revisited.
Sternick EB, Cruz FE, Timmermans C, Sosa EA, Rodriguez LM, Gerken LM, Fagundes ML, Scanavacca MI, Wellens HJ
Heart Rhythm 2004 Oct;1(4):406-13. doi: 10.1016/j.hrthm.2004.06.007. PMID: 15851192
Diagnosis and surgical treatment of tachycardias in patients with nodoventricular fibers.
Bockeria LA, Chigogidze NA, Golukhova EZ, Artjukhina TV
Pacing Clin Electrophysiol 1991 Nov;14(11 Pt 2):2004-9. doi: 10.1111/j.1540-8159.1991.tb02806.x. PMID: 1721215

Recent clinical studies

Etiology

Comprehensive assessment of Mahaim accessory pathways' anatomic distribution.
Gormel S, Yasar S, Yildirim E, Asil S, Baris VO, Gokoglan Y, Celik M, Yuksel UC, Vurgun VK, Kabul HK, Kose S
J Int Med Res 2022 Jan;50(1):3000605211069751. doi: 10.1177/03000605211069751. PMID: 35001697Free PMC Article
Postablation-acquired short atrioventricular Mahaim-type fibers: observations on their clinical, electrocardiographic, and electrophysiologic profile.
Sternick EB, Correa FS, Rego S, Santos DM, Damascena F, Scarpelli R, Gerken LM, Wellens HJ
Heart Rhythm 2012 Jun;9(6):850-8. Epub 2012 Feb 13 doi: 10.1016/j.hrthm.2012.02.011. PMID: 22338671
Mahaim tachycardias.
Aliot E, de Chillou C, Revault d'Allones G, Mabo P, Sadoul N
Eur Heart J 1998 May;19 Suppl E:E25-31, E52-3. PMID: 9717021
Radiofrequency catheter ablation of right atriofascicular (Mahaim) accessory pathways guided by accessory pathway activation potentials.
McClelland JH, Wang X, Beckman KJ, Hazlitt HA, Prior MI, Nakagawa H, Lazzara R, Jackman WM
Circulation 1994 Jun;89(6):2655-66. doi: 10.1161/01.cir.89.6.2655. PMID: 8205678
Radiofrequency catheter ablation of Mahaim fibers at the tricuspid annulus.
Klein LS, Hackett FK, Zipes DP, Miles WM
Circulation 1993 Mar;87(3):738-47. doi: 10.1161/01.cir.87.3.738. PMID: 8443894

Diagnosis

Comparison of electrophysiological characteristics of right- and left-sided Mahaim-type accessory pathways.
Ozcan EE, Turan OE, Akdemir B, Inevi UD, Yilancioglu RY, Baskurt AA, Alak C, Bayrak F
J Cardiovasc Electrophysiol 2021 Feb;32(2):360-369. Epub 2021 Jan 9 doi: 10.1111/jce.14852. PMID: 33355963
Unusual variants of pre-excitation: From anatomy to ablation: Part III-Clinical presentation, electrophysiologic characteristics, when and how to ablate nodoventricular, nodofascicular, fasciculoventricular pathways, along with considerations of permanent junctional reciprocating tachycardia.
Soares Correa F, Lokhandwala Y, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3097-3115. Epub 2019 Nov 14 doi: 10.1111/jce.14247. PMID: 31646696
Part II-Clinical presentation, electrophysiologic characteristics, and when and how to ablate atriofascicular pathways and long and short decrementally conducting accessory pathways.
Soares Correa F, Lokhandwala Y, Cruz Filho F, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3079-3096. Epub 2019 Oct 16 doi: 10.1111/jce.14203. PMID: 31588593
Atypical bypass tracts: can they be recognized during sinus rhythm?
de Alencar Neto JN, Ramalho de Moraes SR, Back Sternick E, Wellens HJJ
Europace 2019 Feb 1;21(2):208-218. doi: 10.1093/europace/euy079. PMID: 29788238
Mahaim tachycardias.
Aliot E, de Chillou C, Revault d'Allones G, Mabo P, Sadoul N
Eur Heart J 1998 May;19 Suppl E:E25-31, E52-3. PMID: 9717021

Therapy

Part II-Clinical presentation, electrophysiologic characteristics, and when and how to ablate atriofascicular pathways and long and short decrementally conducting accessory pathways.
Soares Correa F, Lokhandwala Y, Cruz Filho F, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3079-3096. Epub 2019 Oct 16 doi: 10.1111/jce.14203. PMID: 31588593
Atypical bypass tracts: can they be recognized during sinus rhythm?
de Alencar Neto JN, Ramalho de Moraes SR, Back Sternick E, Wellens HJJ
Europace 2019 Feb 1;21(2):208-218. doi: 10.1093/europace/euy079. PMID: 29788238
Mahaim tachycardias.
Aliot E, de Chillou C, Revault d'Allones G, Mabo P, Sadoul N
Eur Heart J 1998 May;19 Suppl E:E25-31, E52-3. PMID: 9717021
Pathophysiology of supraventricular tachycardia.
Shakespeare CF, Anderson M, Camm AJ
Eur Heart J 1993 Sep;14 Suppl E:2-8. doi: 10.1093/eurheartj/14.suppl_e.2. PMID: 8223750
Flecainide in the Wolff-Parkinson-White syndrome.
Crozier I
Am J Cardiol 1992 Aug 20;70(5):26A-32A. doi: 10.1016/0002-9149(92)91074-e. PMID: 1509995

Prognosis

Unusual variants of pre-excitation: From anatomy to ablation: Part III-Clinical presentation, electrophysiologic characteristics, when and how to ablate nodoventricular, nodofascicular, fasciculoventricular pathways, along with considerations of permanent junctional reciprocating tachycardia.
Soares Correa F, Lokhandwala Y, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3097-3115. Epub 2019 Nov 14 doi: 10.1111/jce.14247. PMID: 31646696
Part II-Clinical presentation, electrophysiologic characteristics, and when and how to ablate atriofascicular pathways and long and short decrementally conducting accessory pathways.
Soares Correa F, Lokhandwala Y, Cruz Filho F, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3079-3096. Epub 2019 Oct 16 doi: 10.1111/jce.14203. PMID: 31588593
Atypical bypass tracts: can they be recognized during sinus rhythm?
de Alencar Neto JN, Ramalho de Moraes SR, Back Sternick E, Wellens HJJ
Europace 2019 Feb 1;21(2):208-218. doi: 10.1093/europace/euy079. PMID: 29788238
Radiofrequency catheter ablation of Mahaim fibers at the tricuspid annulus.
Klein LS, Hackett FK, Zipes DP, Miles WM
Circulation 1993 Mar;87(3):738-47. doi: 10.1161/01.cir.87.3.738. PMID: 8443894
Flecainide in the Wolff-Parkinson-White syndrome.
Crozier I
Am J Cardiol 1992 Aug 20;70(5):26A-32A. doi: 10.1016/0002-9149(92)91074-e. PMID: 1509995

Clinical prediction guides

Comparison of electrophysiological characteristics of right- and left-sided Mahaim-type accessory pathways.
Ozcan EE, Turan OE, Akdemir B, Inevi UD, Yilancioglu RY, Baskurt AA, Alak C, Bayrak F
J Cardiovasc Electrophysiol 2021 Feb;32(2):360-369. Epub 2021 Jan 9 doi: 10.1111/jce.14852. PMID: 33355963
Part II-Clinical presentation, electrophysiologic characteristics, and when and how to ablate atriofascicular pathways and long and short decrementally conducting accessory pathways.
Soares Correa F, Lokhandwala Y, Cruz Filho F, Sánchez-Quintana D, Mori S, Anderson RH, Wellens HJJ, Back Sternick E
J Cardiovasc Electrophysiol 2019 Dec;30(12):3079-3096. Epub 2019 Oct 16 doi: 10.1111/jce.14203. PMID: 31588593
Atypical bypass tracts: can they be recognized during sinus rhythm?
de Alencar Neto JN, Ramalho de Moraes SR, Back Sternick E, Wellens HJJ
Europace 2019 Feb 1;21(2):208-218. doi: 10.1093/europace/euy079. PMID: 29788238
Mahaim tachycardias.
Aliot E, de Chillou C, Revault d'Allones G, Mabo P, Sadoul N
Eur Heart J 1998 May;19 Suppl E:E25-31, E52-3. PMID: 9717021
Flecainide in the Wolff-Parkinson-White syndrome.
Crozier I
Am J Cardiol 1992 Aug 20;70(5):26A-32A. doi: 10.1016/0002-9149(92)91074-e. PMID: 1509995

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...