U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Angiomatosis

MedGen UID:
1931
•Concept ID:
C0002992
•
Disease or Syndrome
Synonym: Angiomatoses
SNOMED CT: Angiomatosis (14350002); Angiomatosis (205562004)
 
Monarch Initiative: MONDO:0024461

Definition

A benign diffuse vascular proliferation usually occurring in young adults. It is characterized by the formation of capillary-sized and cavernous vascular spaces. Patients present with diffuse persistent swelling. [from NCI]

Professional guidelines

PubMed

Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management.
Pinna R, Cocco F, Campus G, Conti G, Milia E, Sardella A, Cagetti MG
Periodontol 2000 2019 Jun;80(1):12-27. doi: 10.1111/prd.12261. PMID: 31090139
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.
Javaid U, Ali MH, Jamal S, Butt NH
Int Ophthalmol 2018 Feb;38(1):409-416. Epub 2017 Jan 7 doi: 10.1007/s10792-016-0412-3. PMID: 28064423
Pathogenicity and treatment of Bartonella infections.
Angelakis E, Raoult D
Int J Antimicrob Agents 2014 Jul;44(1):16-25. Epub 2014 May 9 doi: 10.1016/j.ijantimicag.2014.04.006. PMID: 24933445

Recent clinical studies

Etiology

GNA11-mutated Sturge-Weber syndrome has distinct neurological and dermatological features.
Dompmartin A, van der Vleuten CJM, Dekeuleneer V, Duprez T, Revencu N, Désir J, Te Loo DMWM, Flucke U, Eijkelenboom A, Schultze Kool L, Vikkula M, Boon L
Eur J Neurol 2022 Oct;29(10):3061-3070. Epub 2022 Jul 13 doi: 10.1111/ene.15452. PMID: 35715928
Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management.
Pinna R, Cocco F, Campus G, Conti G, Milia E, Sardella A, Cagetti MG
Periodontol 2000 2019 Jun;80(1):12-27. doi: 10.1111/prd.12261. PMID: 31090139
Chronic hand infections.
Al-Qattan MM, Helmi AA
J Hand Surg Am 2014 Aug;39(8):1636-45. doi: 10.1016/j.jhsa.2014.04.003. PMID: 25070033
Bartonellosis.
Maguiña C, Guerra H, Ventosilla P
Clin Dermatol 2009 May-Jun;27(3):271-80. doi: 10.1016/j.clindermatol.2008.10.006. PMID: 19362689
Bacillary angiomatosis.
Batsakis JG, Ro JY, Frauenhoffer EE
Ann Otol Rhinol Laryngol 1995 Aug;104(8):668-72. doi: 10.1177/000348949510400815. PMID: 7543738

Diagnosis

Diffuse dermal angiomatosis.
Touloei K, Tongdee E, Smirnov B, Nousari C
Cutis 2019 Mar;103(3):181-184. PMID: 31039226
Sturge-Weber Syndrome: A Review.
Higueros E, Roe E, Granell E, Baselga E
Actas Dermosifiliogr 2017 Jun;108(5):407-417. Epub 2017 Jan 23 doi: 10.1016/j.ad.2016.09.022. PMID: 28126187
Bartonellosis.
Maguiña C, Guerra H, Ventosilla P
Clin Dermatol 2009 May-Jun;27(3):271-80. doi: 10.1016/j.clindermatol.2008.10.006. PMID: 19362689
Bacillary angiomatosis.
Batsakis JG, Ro JY, Frauenhoffer EE
Ann Otol Rhinol Laryngol 1995 Aug;104(8):668-72. doi: 10.1177/000348949510400815. PMID: 7543738
Bacillary angiomatosis.
Berger TG, Koehler JE
AIDS Clin Rev 1993-1994:43-60. PMID: 8217903

Therapy

Sturge-Weber Syndrome: A Review.
Higueros E, Roe E, Granell E, Baselga E
Actas Dermosifiliogr 2017 Jun;108(5):407-417. Epub 2017 Jan 23 doi: 10.1016/j.ad.2016.09.022. PMID: 28126187
Pathogenicity and treatment of Bartonella infections.
Angelakis E, Raoult D
Int J Antimicrob Agents 2014 Jul;44(1):16-25. Epub 2014 May 9 doi: 10.1016/j.ijantimicag.2014.04.006. PMID: 24933445
Bartonella-associated infections.
Spach DH, Koehler JE
Infect Dis Clin North Am 1998 Mar;12(1):137-55. doi: 10.1016/s0891-5520(05)70414-1. PMID: 9494835
Bacillary angiomatosis.
Berger TG, Koehler JE
AIDS Clin Rev 1993-1994:43-60. PMID: 8217903
Retinal arterial macroaneurysms.
Rabb MF, Gagliano DA, Teske MP
Surv Ophthalmol 1988 Sep-Oct;33(2):73-96. doi: 10.1016/0039-6257(88)90160-9. PMID: 3055391

Prognosis

Unusual Gigantiform Angiomatosis of Jawbone.
Kumar N, Anehosur V, Desai A, Agrawal S, Prabhu A, Hallikeri K
J Craniofac Surg 2022 May 1;33(3):e230-e233. Epub 2021 Jul 14 doi: 10.1097/SCS.0000000000007967. PMID: 34261965
Sturge-Weber Syndrome: A Review.
Higueros E, Roe E, Granell E, Baselga E
Actas Dermosifiliogr 2017 Jun;108(5):407-417. Epub 2017 Jan 23 doi: 10.1016/j.ad.2016.09.022. PMID: 28126187
Sturge-Weber syndrome: a review.
Thomas-Sohl KA, Vaslow DF, Maria BL
Pediatr Neurol 2004 May;30(5):303-10. doi: 10.1016/j.pediatrneurol.2003.12.015. PMID: 15165630
Bartonella (Rochalimaea) quintana infections.
Maurin M, Raoult D
Clin Microbiol Rev 1996 Jul;9(3):273-92. doi: 10.1128/CMR.9.3.273. PMID: 8809460Free PMC Article
Klippel-Trenaunay syndrome: a review.
You CK, Rees J, Gillis DA, Steeves J
Can J Surg 1983 Sep;26(5):399-403. PMID: 6311389

Clinical prediction guides

Unusual Gigantiform Angiomatosis of Jawbone.
Kumar N, Anehosur V, Desai A, Agrawal S, Prabhu A, Hallikeri K
J Craniofac Surg 2022 May 1;33(3):e230-e233. Epub 2021 Jul 14 doi: 10.1097/SCS.0000000000007967. PMID: 34261965
Cat Scratch Disease and Bartonellaceae: The Known, the Unknown and the Curious.
Zangwill KM
Pediatr Infect Dis J 2021 May 1;40(5S):S11-S15. doi: 10.1097/INF.0000000000002776. PMID: 34042905
Infectious Angiogenesis-Different Pathways, the Same Goal.
Urbanowicz M, Kutzner H, Riveiro-Falkenbach E, Rodriguez-Peralto JL
Am J Dermatopathol 2016 Nov;38(11):793-801. doi: 10.1097/DAD.0000000000000577. PMID: 27258788
Clinical impact of persistent Bartonella bacteremia in humans and animals.
Chomel BB, Kasten RW, Sykes JE, Boulouis HJ, Breitschwerdt EB
Ann N Y Acad Sci 2003 Jun;990:267-78. doi: 10.1111/j.1749-6632.2003.tb07376.x. PMID: 12860639
Treatment of cat-scratch disease.
Conrad DA
Curr Opin Pediatr 2001 Feb;13(1):56-9. doi: 10.1097/00008480-200102000-00010. PMID: 11176245

Recent systematic reviews

Meningioangiomatosis: Multimodal Analysis and Insights From a Systematic Review.
Roux A, Zanello M, Mancusi RL, Still MEH, Nascimento FA, Tauziede-Espariat A, Huberfeld G, Zah-Bi G, Dezamis E, Meder JF, Bourgeois M, Parraga E, Chretien F, Varlet P, Oppenheim C, Lechapt-Zalcman E, Pallud J
Neurology 2021 Feb 9;96(6):274-286. Epub 2020 Dec 22 doi: 10.1212/WNL.0000000000011372. PMID: 33361266
Systematic review of mortality associated with neonatal primary staged closure of giant omphalocele.
Barrios Sanjuanelo A, Abelló Munarriz C, Cardona-Arias JA
J Pediatr Surg 2021 Apr;56(4):678-685. Epub 2020 Aug 29 doi: 10.1016/j.jpedsurg.2020.08.019. PMID: 32981659
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.
Javaid U, Ali MH, Jamal S, Butt NH
Int Ophthalmol 2018 Feb;38(1):409-416. Epub 2017 Jan 7 doi: 10.1007/s10792-016-0412-3. PMID: 28064423
The prevalence of the extensor digitorum communis tendon and its insertion variants: a systematic review and meta-analysis.
Yammine K
Clin Anat 2014 Nov;27(8):1284-90. Epub 2014 Jun 23 doi: 10.1002/ca.22429. PMID: 24953717
Treatment outcomes of human bartonellosis: a systematic review and meta-analysis.
Prutsky G, Domecq JP, Mori L, Bebko S, Matzumura M, Sabouni A, Shahrour A, Erwin PJ, Boyce TG, Montori VM, Malaga G, Murad MH
Int J Infect Dis 2013 Oct;17(10):e811-9. Epub 2013 Apr 18 doi: 10.1016/j.ijid.2013.02.016. PMID: 23602630

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...