U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Childhood testicular germ cell tumor

MedGen UID:
208758
Concept ID:
C0796663
Neoplastic Process
Synonyms: Childhood Testicular Germ Cell Neoplasm; childhood testicular germ cell neoplasm; Childhood Testicular Germ Cell Tumor; childhood testicular germ cell tumor; paediatric testicular germ cell neoplasm; paediatric testicular germ cell tumour; Pediatric Testicular Germ Cell Neoplasm; pediatric testicular germ cell neoplasm; Pediatric Testicular Germ Cell Tumor; pediatric testicular germ cell tumor; testicular germ cell tumor of childhood; testicular germ cell tumour of childhood
 
Monarch Initiative: MONDO:0003758

Definition

A germ cell tumor that arises from the testis during childhood. [from NCI]

Professional guidelines

PubMed

Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647
Ping P, Gu BH, Li P, Huang YR, Li Z
Asian J Androl 2014 Jan-Feb;16(1):107-11. doi: 10.4103/1008-682X.122194. PMID: 24369141Free PMC Article

Recent clinical studies

Etiology

Lengert AVH, Pereira LDNB, Cabral ERM, Gomes INF, Jesus LM, Gonçalves MFS, Rocha AOD, Tassinari TA, Silva LSD, Laus AC, Vidal DO, Pinto MT, Reis RM, Lopes LF
Front Biosci (Landmark Ed) 2022 Aug 16;27(8):245. doi: 10.31083/j.fbl2708245. PMID: 36042160
Aldrink JH, Glick RD, Baertschiger RM, Kulaylat AN, Lautz TB, Christison-Lagay E, Grant CN, Tracy E, Dasgupta R, Brown EG, Mattei P, Rothstein DH, Rodeberg DA, Ehrlich PF
J Pediatr Surg 2022 Apr;57(4):690-699. Epub 2021 Apr 15 doi: 10.1016/j.jpedsurg.2021.04.001. PMID: 33975708
Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
McGlynn KA, Petrick JL, Gamborg M, Aarestrup J, Baker JL
Int J Cancer 2018 Aug 15;143(4):767-772. Epub 2018 Mar 26 doi: 10.1002/ijc.31354. PMID: 29508384Free PMC Article
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647

Diagnosis

Lengert AVH, Pereira LDNB, Cabral ERM, Gomes INF, Jesus LM, Gonçalves MFS, Rocha AOD, Tassinari TA, Silva LSD, Laus AC, Vidal DO, Pinto MT, Reis RM, Lopes LF
Front Biosci (Landmark Ed) 2022 Aug 16;27(8):245. doi: 10.31083/j.fbl2708245. PMID: 36042160
Aldrink JH, Glick RD, Baertschiger RM, Kulaylat AN, Lautz TB, Christison-Lagay E, Grant CN, Tracy E, Dasgupta R, Brown EG, Mattei P, Rothstein DH, Rodeberg DA, Ehrlich PF
J Pediatr Surg 2022 Apr;57(4):690-699. Epub 2021 Apr 15 doi: 10.1016/j.jpedsurg.2021.04.001. PMID: 33975708
Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
McGlynn KA, Petrick JL, Gamborg M, Aarestrup J, Baker JL
Int J Cancer 2018 Aug 15;143(4):767-772. Epub 2018 Mar 26 doi: 10.1002/ijc.31354. PMID: 29508384Free PMC Article
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647

Therapy

Florou M, Tsilidis KK, Siomou E, Koletsa T, Syrnioti A, Spyridakis I, Kaselas C, Ntzani EE
Eur J Pediatr 2023 Jun;182(6):2499-2507. Epub 2023 Mar 29 doi: 10.1007/s00431-023-04947-9. PMID: 36988678
Lengert AVH, Pereira LDNB, Cabral ERM, Gomes INF, Jesus LM, Gonçalves MFS, Rocha AOD, Tassinari TA, Silva LSD, Laus AC, Vidal DO, Pinto MT, Reis RM, Lopes LF
Front Biosci (Landmark Ed) 2022 Aug 16;27(8):245. doi: 10.31083/j.fbl2708245. PMID: 36042160
Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
Levy M, Hall D, Sud A, Law P, Litchfield K, Dudakia D, Haugen TB, Karlsson R, Reid A, Huddart RA, Grotmol T, Wiklund F, Houlston RS, Turnbull C
Andrology 2017 Sep;5(5):914-922. Epub 2017 Aug 13 doi: 10.1111/andr.12388. PMID: 28804972
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647

Prognosis

Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647
Pauniaho SL, Salonen J, Helminen M, Heikinheimo O, Vettenranta K, Heikinheimo M
Cancer Causes Control 2014 Oct;25(10):1337-41. Epub 2014 Jul 25 doi: 10.1007/s10552-014-0439-6. PMID: 25060481
Richiardi L, Vizzini L, Pastore G, Segnan N, Gillio-Tos A, Fiano V, Grasso C, Ciuffreda L, Lista P, Pearce N, Merletti F
Int J Cancer 2014 Aug 1;135(3):695-701. Epub 2014 Jan 10 doi: 10.1002/ijc.28688. PMID: 24375202
Price NR, Charlton A, Simango I, Smith GH
J Paediatr Child Health 2014 Oct;50(10):E102-5. Epub 2011 Mar 10 doi: 10.1111/j.1440-1754.2011.02021.x. PMID: 21392148

Clinical prediction guides

Florou M, Tsilidis KK, Siomou E, Koletsa T, Syrnioti A, Spyridakis I, Kaselas C, Ntzani EE
Eur J Pediatr 2023 Jun;182(6):2499-2507. Epub 2023 Mar 29 doi: 10.1007/s00431-023-04947-9. PMID: 36988678
McGlynn KA, Petrick JL, Gamborg M, Aarestrup J, Baker JL
Int J Cancer 2018 Aug 15;143(4):767-772. Epub 2018 Mar 26 doi: 10.1002/ijc.31354. PMID: 29508384Free PMC Article
Litchfield K, Levy M, Huddart RA, Shipley J, Turnbull C
Nat Rev Urol 2016 Jul;13(7):409-19. Epub 2016 Jun 14 doi: 10.1038/nrurol.2016.107. PMID: 27296647
Oosterhuis JW, Stoop JA, Rijlaarsdam MA, Biermann K, Smit VT, Hersmus R, Looijenga LH
Andrology 2015 Jan;3(1):70-7. Epub 2014 Nov 27 doi: 10.1111/andr.305. PMID: 25427839
Sakashita S, Koyanagi T, Tsuji I, Arikado K, Matsuno T
J Urol 1980 Dec;124(6):889-91. doi: 10.1016/s0022-5347(17)55714-6. PMID: 6449607

Recent systematic reviews

Florou M, Tsilidis KK, Siomou E, Koletsa T, Syrnioti A, Spyridakis I, Kaselas C, Ntzani EE
Eur J Pediatr 2023 Jun;182(6):2499-2507. Epub 2023 Mar 29 doi: 10.1007/s00431-023-04947-9. PMID: 36988678

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...